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VH 101, thiol

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-47851
    VH 101, thiol

    		Ligands for E3 Ligase Cancer
    VH 101, thiol (compound 20) is a VHL ligand for the synthesis of PROTACs .
    <em>VH</em> <em>101</em>, <em>thiol</em>
  • HY-148030
    XL01126

    		PROTACs LRRK2 Neurological Disease
    XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)) composed of the VHL ligand VH 101, thiol (HY-47851, blue part) and the LRRK2 inhibitor HG-10-102-01 (HY-13488, red part). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2 .
    XL01126

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