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VU 0152099

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*VU0152099*	mAChR	Neurological Disease
VU0152099 is a potent, selective and brain-penetrant mAChR M4 positive allosteric modulator with an EC₅₀ of 0.4 µM for rat M4 receptor. VU0152099 is inactive for other mAChR subtypes or other GPCRs. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine .

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