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Veledimex

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16785

    INXN-1001; RG-115932

    Interleukin Related Inflammation/Immunology Cancer
    Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
    Veledimex
  • HY-16785B

    INXN-1001 (S enantiomer); RG-115932 (S enantiomer)

    Interleukin Related Cancer
    Veledimex S enantiomer (INXN-1001 S enantiomer) is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system, and a moderate inhibitor of and substrate for CYP3A4/5 .
    Veledimex (S enantiomer)
  • HY-16785A

    INXN-1001 racemate; RG-115932 racemate

    Interleukin Related Inflammation/Immunology Cancer
    Veledimex racemate (INXN-1001 racemate) is the racemate of veledimex. Veledimex is an orally available, small-molecule activator ligand for the RheoSwitch Therapeutic System .
    Veledimex racemate

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