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Results for "

Wy21743

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0808
    Oxaprozin

    Oxaprozinum; Wy21743

    		 COX NF-κB Akt IKK Apoptosis Inflammation/Immunology Cancer
    Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
    Oxaprozin
  • HY-B0808S
    Oxaprozin-d4

    Wy-21743-d4

    		 COX Others
    Oxaprozin-d4 is the deuterium labeled Oxaprozin, which is a non-steroidal anti-inflammatory agent (NSAID).
    Oxaprozin-d4
  • HY-B0808A
    Oxaprozin potassium

    Oxaprozinum potassium; Wy21743 potassium

    		 COX NF-κB Akt IKK Apoptosis Inflammation/Immunology Cancer
    Oxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-κB. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
    Oxaprozin potassium
  • HY-B0808R
    Oxaprozin (Standard)

    Oxaprozinum (Standard); Wy21743 (Standard)

    		 COX NF-κB Akt IKK Apoptosis Inflammation/Immunology Cancer
    Oxaprozin (Standard) is the analytical standard of Oxaprozin. This product is intended for research and analytical applications. Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
    Oxaprozin (Standard)
  • HY-B0808S1
    Oxaprozin-d5

    Oxaprozinum-d5; Wy21743-d5

    		 Isotope-Labeled Compounds COX NF-κB Inflammation/Immunology Cancer
    Oxaprozin-d5 is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.
    Oxaprozin-d5

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