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Z-D-Glu-Obzl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Biochemical Assay Reagents (1) Fluorescent Dye (4) HIV (1) Ser/Thr Protease (1)
By Research Areas:	Cardiovascular Disease (2) Infection (1)

7

Inhibitors & Agonists

7

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Z-D-Glu-Obzl*	Amino Acid Derivatives	Others
Z-D-Glu-Obzl is a derivative of D-Glu, can be used for synthesis of compounds .

*Boc-Glu(OBzl)-OH*	Biochemical Assay Reagents	Others
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .

*Boc-Asp(OBzl)-Pro-Arg-AMC acetate*	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

*Boc-Asp(OBzl)-Pro-Arg-AMC*	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively .

*Boc-Glu(OBzl)-Gly-Arg-AMC*	Fluorescent Dye	Cardiovascular Disease
Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

*Boc-Glu(OBzl)-Ala-Arg-AMC*	Fluorescent Dye Ser/Thr Protease	Cardiovascular Disease
Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

*[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)*	HIV	Infection
[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) is a selective inhibitor of HIV-1. [(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) inhibits viral infection and cell fusion by blocking the interaction between HIV-1 and CD4 molecules. [(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) can completely inhibit fusion formation at a concentration of 25 μM .

Cat. No.	Product Name	Target	Research Area

*Z-D-Glu-Obzl*	Amino Acid Derivatives	Others
Z-D-Glu-Obzl is a derivative of D-Glu, can be used for synthesis of compounds .

*Boc-Glu(OBzl)-OH*	Biochemical Assay Reagents	Others
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .

*Boc-Asp(OBzl)-Pro-Arg-AMC acetate*	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

*Boc-Asp(OBzl)-Pro-Arg-AMC*	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively .

*Boc-Glu(OBzl)-Gly-Arg-AMC*	Fluorescent Dye	Cardiovascular Disease
Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

*Boc-Glu(OBzl)-Ala-Arg-AMC*	Fluorescent Dye Ser/Thr Protease	Cardiovascular Disease
Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

*[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)*	HIV	Infection
[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) is a selective inhibitor of HIV-1. [(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) inhibits viral infection and cell fusion by blocking the interaction between HIV-1 and CD4 molecules. [(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) can completely inhibit fusion formation at a concentration of 25 μM .

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