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acetylated derivative

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By Targets:	Akt (1) Amino Acid Derivatives (1) Biochemical Assay Reagents (3) Endogenous Metabolite (2) Fluorescent Dye (1) Isotope-Labeled Compounds (1) Molecular Glues (1) PI3K (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (3) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-59291

Levacetylleucine	Endogenous Metabolite Amino Acid Derivatives	Neurological Disease Metabolic Disease Inflammation/Immunology
Levacetylleucine, an orally bioavailable and brain-penetrant endogenous metabolite, is an acetylated derivative of amino acid leucine. Levacetylleucine is the active form of N-acetyl-leucine (NAL). Levacetylleucine attenuates neuronal death and neuroinflammation in the cortical tissue of mice. Levacetylleucine also potentially improves ameliorates lysosomal and metabolic dysfunction. Levacetylleucine improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats. Levacetylleucine is promising for research of neurological manifestations of Niemann-Pick disease type C, traumatic brain injury and neurodegeneration prevention .

HY-N7138

2-(Phosphonooxy)benzoic acid	Others	Neurological Disease Inflammation/Immunology
2-(Phosphonooxy)benzoic acid is a non-acetylated salicylic acid derivative which has the potential for inflammatory disease as well as in analgesic therapy .

HY-N6685S1

3-Acetyldeoxynivalenol-13C17	Isotope-Labeled Compounds	Cardiovascular Disease
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-164066

Sodium Acetylated Hyaluronate	Biochemical Assay Reagents	Others
Sodium Acetylated Hyaluronate is an acetylated hyaluronic acid derivative with anti-wrinkle and deep skin penetration properties, which can be used in skin aging research and cosmetic development .

HY-W095697

N-Acetylhistidine	Endogenous Metabolite	Others
N-Acetylhistidine is a histidine derivative that is the acetylated enzyme intermediate in the N-acetyltransferase reaction .

HY-N6685

3-Acetyldeoxynivalenol	Others	Cardiovascular Disease
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-W039943

Acetyl-cyclosporin A aldehyde	Molecular Glues	Cancer
Acetyl-cyclosporin A aldehyde is an acetylated Cyclosporin A (HY-B0579) derivative with a reducing aldehyde group. Cyclosporin A is a potent calmodulin inhibitor and cyclophilin binder that can target the nuclear translocation of NF-AT and cause mitochondrial damage.

HY-N6685R

3-Acetyldeoxynivalenol (Standard)	Others	Cardiovascular Disease
3-Acetyldeoxynivalenol (Standard) is the analytical standard of 3-Acetyldeoxynivalenol. This product is intended for research and analytical applications. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-D2379A

closed-HMRG	Fluorescent Dye
closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent .

HY-P4790

Acetyl-Exenatide	PI3K Akt	Metabolic Disease
Acetyl-Exenatideyes is an acetylated derivative of Exenatide. Exenatide has the function similar to insulin, which can be used for research of type 2 diabetes. Exenatide can promote Th17 differentiation, inhibits Tregs differentiation, downregulates PI3K/Akt/FoxO1 phosphorylation .

HY-W744098

1-Dehydrocorticosterone 21-acetate 1-DHC 21-acetate	Others	Metabolic Disease
1-Dehydrocorticosterone 21-acetate is an acetylated derivative of corticosterone (HY-B1618) that is dehydrogenated at the one position. It has been used as a precursor in the synthesis of 21-hydroxypregna-1,4-diene-3,11,20-trione, which is a metabolite of 1α-hydroxycorticosterone in the skate.

HY-119309

Sucrose octaacetate	Biochemical Assay Reagents	Others
Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .

HY-119309R

Sucrose octaacetate (Standard)	Biochemical Assay Reagents	Others
Sucrose octaacetate (Standard) is the analytical standard of Sucrose octaacetate. This product is intended for research and analytical applications. Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .

Cat. No.	Product Name	Type

HY-D2379A

closed-HMRG	Fluorescent Dyes/Probes
closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent .

Cat. No.	Product Name	Target	Research Area

HY-P4790

Acetyl-Exenatide	PI3K Akt	Metabolic Disease
Acetyl-Exenatideyes is an acetylated derivative of Exenatide. Exenatide has the function similar to insulin, which can be used for research of type 2 diabetes. Exenatide can promote Th17 differentiation, inhibits Tregs differentiation, downregulates PI3K/Akt/FoxO1 phosphorylation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-59291

Levacetylleucine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Amino Acid Derivatives
Levacetylleucine, an orally bioavailable and brain-penetrant endogenous metabolite, is an acetylated derivative of amino acid leucine. Levacetylleucine is the active form of N-acetyl-leucine (NAL). Levacetylleucine attenuates neuronal death and neuroinflammation in the cortical tissue of mice. Levacetylleucine also potentially improves ameliorates lysosomal and metabolic dysfunction. Levacetylleucine improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats. Levacetylleucine is promising for research of neurological manifestations of Niemann-Pick disease type C, traumatic brain injury and neurodegeneration prevention .

HY-W095697

N-Acetylhistidine	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
N-Acetylhistidine is a histidine derivative that is the acetylated enzyme intermediate in the N-acetyltransferase reaction .

HY-N6685

3-Acetyldeoxynivalenol	Cardiovascular Disease Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Others
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N6685R

3-Acetyldeoxynivalenol (Standard)	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Others
3-Acetyldeoxynivalenol (Standard) is the analytical standard of 3-Acetyldeoxynivalenol. This product is intended for research and analytical applications. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

Cat. No.	Product Name	Chemical Structure

HY-N6685S1

3-Acetyldeoxynivalenol-13C17
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

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acetylated derivative

Inhibitors & Agonists

Fluorescent Dye

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products