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Results for "

acetylated lysine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Epigenetic Reader Domain (1) MDM-2/p53 (1)
By Research Areas:	Cancer (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145550

Amredobresib BI894999	Epigenetic Reader Domain	Cancer
Amredobresib is a potent inhibitor of BET. Amredobresib inhibits the binding of bromodomains to acetylated lysines on histone H3 and H4 and thus acts as important regulators of gene transcription. Amredobresib is useful for the research of acute myeloid leukemia (AML) and cancer (extracted from patent WO2019145410A1 and WO2021175824A1) .

HY-159606

MS182	MDM-2/p53	Cancer
MS182 (compound 11) is an acetylation targeting chimera (AceTAC) designed based on p53 ^Y220C stabilizer and targeting p53 ^Y220C. MS182 is composed of p53 ^Y220C and p300/CBP binders, respectively, coupled by a linker. MS182 forms a ternary complex with p300/CBP acetyltransferase and p53 ^Y220C in a time- and concentration-dependent manner, effectively acetylating lysine at position 382 of p53 ^Y220C (ACE₅₀: 1.52 μM). MS182 also exhibited considerable bioavailability in mice, with GI₅₀ values of 2.16 μM and 1.83 μM for BxPC3 (p53 ^Y220C/-) and NUGC (p53 ^Y220C/+), respectively .

Cat. No.	Product Name	Type

HY-154818

Bovine Serum Albumin, Acetylated Ac-BSA	Native Proteins
Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

Bovine Serum Albumin, Acetylated

Ac-BSA

Native Proteins

Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

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