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Results for "

adamantane

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2427
    Adamantane

    		Others Others
    Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
    Adamantane
  • HY-W016473
    Adamantane-carboxylic acid

    		Bacterial Infection
    Adamantane-carboxylic acid is an antibacterial agent that is effective in inhibiting the growth of Gram-positive bacteria but is less sensitive to Gram-negative bacteria .
    Adamantane-carboxylic acid
  • HY-B1044
    Idramantone

    Kemantane; 5-Hydroxy-2-adamantanone

    		 Others Neurological Disease
    Idramantone (Kemantane), an Adamantane derivative, is an immunostimulant .
    Idramantone
  • HY-Y0531
    1-Adamantanol

    1-Adamantanol

    		 Biochemical Assay Reagents Others
    1-Adamantanol is a cyclic molecule with a hydroxyl group that can be used as an intermediate in the synthesis of adamantane. 1-Adamantanol can be oxidized to 1,3-adamantanediol by the Streptomyces SA8 oxidation system .
    1-Adamantanol
  • HY-N2427R
    Adamantane (Standard)

    		Others Others
    Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
    Adamantane (Standard)
  • HY-168682
    Adamantane-Butyl alcohol

    		Target Protein Ligand-Linker Conjugates Cancer
    Adamantane-Butyl alcohol is a selective and persistent degrader targeting the CDK8-cyclin C complex. Adamantane-Butyl alcohol is the linker for LL-K8-22 (PROTAC CDK8-cyclin C, HY-149209) and HyT .
    Adamantane-Butyl alcohol
  • HY-161933
    1-Adamantane-amide-C7-NH2

    		PROTAC Linkers Cancer
    1-Adamantane-amide-C7-NH2 is the linker, which can be used for syntheisis of PROTAC GPX4 degrader-3 (HY-161930) .
    1-Adamantane-amide-C7-NH2
  • HY-W674002
    1-Adamantylphosphaethyne

    1-(2-Phosphaethynyl)adamantane

    		 Others
    1-Adamantylphosphaethyne (1-(2-Phosphaethynyl)adamantane) is a compound with potential biological activity and can be used as a catalyst in organic synthesis. 1-Adamantylphosphaethyne has shown the ability to induce cell apoptosis in compound development, which helps in anti-tumor inhibition. 1-Adamantylphosphaethyne can also be used as an efficient reaction intermediate to promote the progress of various chemical reactions.
    1-Adamantylphosphaethyne
  • HY-155466
    Boc-MIF-1-Am

    		Dopamine Receptor Neurological Disease
    Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells .
    Boc-MIF-1-Am
  • HY-164988
    TX2-120-1

    		EGFR Cancer
    TX2-120-1 possesses the ability to bind to Her3, with an IC50 value of 56 nM for Her3. TX2-120-1 can be used for the synthesis of TX2-121-1 (HY-118998) .
    TX2-120-1
  • HY-118998
    TX2-121-1

    		PROTACs EGFR ERK Akt Cancer
    TX2-121-1 is a potent and selective Her3 (ErbB3) PROTAC degrader that contains a hydrophobic adamantane moiety. TX2-121-1 is composed of a Her3 inhibitor (HY-164988) and Adamantane (HY-N2427). TX2-121-1 has an IC50 of 49 nM for Her3. TX2-121-1 inhibits Her3-dependent signaling and heterodimerization of Her3. TX2-121-1 has the ability to inhibit cell proliferation. TX2-121-1 can be used in the study of tumors .
    TX2-121-1
  • HY-100547
    IEM-1754

    		iGluR Neurological Disease
    IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
    IEM-1754
  • HY-W395779
    EBOV-IN-1

    		Filovirus Infection
    EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM .
    EBOV-IN-1
  • HY-157090
    AChE/MAO-B-IN-6

    		Monoamine Oxidase Cholinesterase (ChE) Neurological Disease
    AChE/MAO-B-IN-6 (compound 3a) is a dual inhibitor of AChE and h-MAO-B with potential to inhibit Alzheimer's disease .
    AChE/MAO-B-IN-6

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