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amino acid metabolism disorder

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162864
    JX237

    		Endogenous Metabolite Metabolic Disease
    JX237 is an inhibitor of the epithelial neutral amino acid transporter B 0AT1 (SLC6A19) with an IC50 value of 31 nM. JX237 is the main transporter for the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. By inhibiting B 0AT1, JX237 can help normalize elevated plasma amino acids in rare amino acid metabolic disorders like phenylketonuria and urea cycle disorders .
    JX237

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