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Results for "

ansamycins

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (2) Antibiotic (14) Bacterial (11) Drug Intermediate (1) HSP (2) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (5) Infection (13)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108486

Herbimycin A	Bacterial Antibiotic	Infection
Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 ^v-src and p210 ^BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.

HY-17025

Rifabutin 5+ Cited Publications Ansamycin; LM-427	Bacterial Antibiotic	Infection
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-W077634

3-Amino-5-hydroxybenzoic acid AHBA	Drug Intermediate	Infection
3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .

HY-17025S

Rifabutin-d7 Ansamycin-d₇; LM-427-d₇	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-129312

Awamycin	Antibiotic	Cancer
Awamycin is an antitumor ansamycin antibiotic .

HY-17025R

Rifabutin (Standard)	Bacterial Antibiotic	Infection
Rifabutin (Standard) is the analytical standard of Rifabutin. This product is intended for research and analytical applications. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-N14909

Actamycin	Antibiotic Bacterial	Infection
Actamycin is an ansamycin antibiotic with antibacterial activities .

HY-126935

Ansatrienin A3	Others	Others
Ansatrienin A3, also known as Mycotrienin, is a minor component of the ansamycin complex produced by Streptomyces collinus.

HY-139106

N-Demethylansamitocin P-3	Antibiotic	Others
N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361 .

HY-123716

Rubradirin B	Antibiotic Bacterial	Infection
Rubradirin B is an antibiotic, which inhibits a variety of Gram-positive bacteria and Haemophilus influenza. Rubradirin B affects the ribosome functions .

HY-117180

Diastovaricin I 30-Hydroxy-naphthomycin C	Antibiotic	Infection Cancer
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .

HY-B1907A

Rifamycin Rifamycin SV	Bacterial Antibiotic	Infection
Rifamycin (Rifamycin SV) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .

HY-122306

Ansatrienin B Mycotrienin II	Antibiotic Bacterial	Infection Cancer
Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .

HY-B1907

Rifamycin sodium Rifamycin SV sodium	Bacterial Antibiotic	Infection
Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .

HY-133571A

Aminohexylgeldanamycin hydrochloride AHGDM hydrochloride	HSP ADC Cytotoxin	Cancer
Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities .

HY-133571

Aminohexylgeldanamycin AHGDM	HSP ADC Cytotoxin	Cancer
Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities .

HY-B1907R

Rifamycin (sodium) (Standard)	Bacterial Antibiotic	Infection
Rifamycin (sodium) (Standard) is the analytical standard of Rifamycin (sodium). This product is intended for research and analytical applications. Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .

HY-162836

Rifamycin B 4-O-(Carboxymethyl)-Rifamycin	Antibiotic Bacterial	Infection
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-108486

Herbimycin A	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Disease Research Fields	Bacterial Antibiotic
Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 ^v-src and p210 ^BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.

HY-B1907

Rifamycin sodium Rifamycin SV sodium	Infection Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .

HY-129312

Awamycin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic
Awamycin is an antitumor ansamycin antibiotic .

HY-N14909

Actamycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Actamycin is an ansamycin antibiotic with antibacterial activities .

HY-126935

Ansatrienin A3	Structural Classification Natural Products Microorganisms Source classification	Others
Ansatrienin A3, also known as Mycotrienin, is a minor component of the ansamycin complex produced by Streptomyces collinus.

HY-139106

N-Demethylansamitocin P-3	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Other Diseases Disease Research Anticancer Disease Research Fields Other Antibiotics	Antibiotic
N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361 .

HY-123716

Rubradirin B	Structural Classification Microorganisms Source classification Coumarins Phenylpropanoids	Antibiotic Bacterial
Rubradirin B is an antibiotic, which inhibits a variety of Gram-positive bacteria and Haemophilus influenza. Rubradirin B affects the ribosome functions .

HY-117180

Diastovaricin I 30-Hydroxy-naphthomycin C	Structural Classification Macrolide Antibiotics Antibiotics Source classification Endogenous metabolite	Antibiotic
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .

HY-B1907R

Rifamycin (sodium) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Rifamycin (sodium) (Standard) is the analytical standard of Rifamycin (sodium). This product is intended for research and analytical applications. Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria .

Cat. No.	Product Name	Chemical Structure

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

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ansamycins

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products