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Pathways Recommended: Anti-infection
Results for "

anti- MAC

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

2

Inhibitory Antibodies

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-110073
    iMAC2 hydrochloride

    		Apoptosis Inflammation/Immunology Cancer
    iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release .
    iMAC2 hydrochloride
  • HY-P9914
    Eculizumab

    anti-Human C5, Humanized antibody

    		 Complement System Cardiovascular Disease Cancer
    Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research .
    Eculizumab
  • HY-113729
    B 746

    		Bacterial Infection
    B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin .
    B 746
  • HY-159563
    Mal-va-mac-SN38

    		Drug-Linker Conjugates for ADC Cancer
    Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect .
    Mal-va-mac-SN38
  • HY-P10547
    Macropin

    MAC-1 peptide

    		 Bacterial Infection
    Macropin (MAC-1 peptide) is an antimicrobial peptide found in the venom of the solitary bee Macropis fulvipes. Macropin has antibacterial activity against both Gram-positive and Gram-negative bacteria, and also exhibits inhibitory activity against fungi and moderate hemolytic activity against human erythrocytes. Macropin can be used in research on anti-infective therapy .
    Macropin
  • HY-103272
    iMAC2

    		Apoptosis Bacterial Others
    iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release .
    iMAC2

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