2. Immunology/Inflammation
  3. Complement System
  4. Eculizumab

Eculizumab  (Synonyms: Anti-Human C5, Humanized Antibody)

Cat. No.: HY-P9914 Purity: 97.81%
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Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research.

For research use only. We do not sell to patients.

CAS No. : 219685-50-4

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1 mg USD 220 In-stock
5 mg USD 700 In-stock
10 mg USD 1120 In-stock
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Based on 1 publication(s) in Google Scholar

Eculizumab Related Antibodies

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Description

Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Humanized
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Eculizumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-G4-kappa
Purity & Documentation
References
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Eculizumab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eculizumab219685-50-4Anti-Human C5, Humanized AntibodyComplement Systemhumanized monoclonal antibodycomplement C5C5aC5bmembrane attack complexMAChaemolysisInhibitorinhibitorinhibit

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