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Results for "

anti-allergic agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (2) Bacterial (2) Calcium Channel (2) Calmodulin (1) Caspase (1) Drug Metabolite (3) Glucocorticoid Receptor (3) GPR35 (1) GSK-3 (2) Histamine Receptor (16) Interleukin Related (2) Isotope-Labeled Compounds (2) JAK (2) Mas-related G-protein-coupled Receptor (MRGPR) (2) NF-κB (3) p38 MAPK (3) PGE synthase (1) Phosphodiesterase (PDE) (2) Reactive Oxygen Species (2) Src (1) STAT (2) TNF Receptor (3) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (6) Infection (2) Inflammation/Immunology (45) Neurological Disease (2)

By Targets:

Autophagy (2)

Bacterial (2)

Calcium Channel (2)

Calmodulin (1)

Caspase (1)

Drug Metabolite (3)

Glucocorticoid Receptor (3)

GPR35 (1)

GSK-3 (2)

Histamine Receptor (16)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

JAK (2)

Mas-related G-protein-coupled Receptor (MRGPR) (2)

NF-κB (3)

p38 MAPK (3)

PGE synthase (1)

Phosphodiesterase (PDE) (2)

Reactive Oxygen Species (2)

Src (1)

STAT (2)

TNF Receptor (3)

Toll-like Receptor (TLR) (2)

By Research Areas:

Cancer (6)

Cardiovascular Disease (1)

Endocrinology (6)

Infection (2)

Inflammation/Immunology (45)

Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0575

Pinocembrin 5 Publications Verification (+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone	Bacterial Reactive Oxygen Species Autophagy	Infection Inflammation/Immunology Cancer
Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties .

HY-115723

Antiallergic agent-1	Src	Inflammation/Immunology
Antiallergic agent-1, a Src-family kinase inhibitor, may serve as a new valuable lead compound for future antiallergic agent discovery. Antiallergic agent-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-106924A

Antiallergic agent-3	Others	Inflammation/Immunology
Antiallergic agent-3 is a derivative of 2-(benzimidazol-2-yl)-1,3-diaminopropane with antiallergic activity .

HY-145891

B10-S	Others	Inflammation/Immunology
B10-S is a potent anti-allergic agent. B10-S can inhibit the degranulation of LAD2 induced by substance P .

HY-145892

MrgprX2 antagonist-6	Mas-related G-protein-coupled Receptor (MRGPR)	Inflammation/Immunology
MrgprX2 antagonist-6 (compound 9) is an anti-allergic agent. MrgprX2 antagonist-6 shows excellent anti-allergy effects and can inhibit mast cell degranulation .

HY-145893

MrgprX2 antagonist-7	Mas-related G-protein-coupled Receptor (MRGPR)	Inflammation/Immunology
MrgprX2 antagonist-7 (compound 10) is an anti-allergic agent. MrgprX2 antagonist-7 shows excellent anti-allergy effects and can inhibit mast cell degranulation .

HY-123013

Y 9000	Others	Inflammation/Immunology
Y 9000 is an orally active anti-allergic agent .

HY-125360

Mazipredone free base	Glucocorticoid Receptor	Inflammation/Immunology
Mazipredone free base, a glucocorticoid derivative, is an anti-inflammatory and anti-allergic agent. Mazipredone free base is sensitive to oxidation, acidic and basic media .

HY-131274

Fexofenadine Impurity F	Drug Metabolite	Others
Fexofenadine Impurity F is the impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .

HY-106358A

Andolast CR 2039; Dizolast	Phosphodiesterase (PDE)	Inflammation/Immunology
Andolast (CR 2039) is an *anti-allergic* agent. Andolast can inhibit cAMP-phosphodiesterase with an IC₅₀ value of 50 μM. Andolast can be used for the research of asthma .

HY-109544

Repirinast MY-5116	Histamine Receptor	Inflammation/Immunology
Repirinast (MY-5116) is an orally active anti-allergic agent. Repirinast inhibits histamine release. Repirinast can be used in the research of bronchial asthma .

HY-106358

Andolast free base CR 2039 free base; Dizolast free base	Phosphodiesterase (PDE)	Inflammation/Immunology
Andolast (CR 2039) (free base) is an *anti-allergic* agent. Andolast can inhibit cAMP-phosphodiesterase with an IC₅₀ value of 50 μM. Andolast can be used for the research of asthma .

HY-N1221

Stigmast-4-en-3,6-dione	Others	Inflammation/Immunology
Stigmast-4-en-3,6-dione is an anti-inflammatory and anti-allergic agent which can be extracted from Hibiscus cannabinus and Piper betle .

HY-100657

meta-Fexofenadine meta-MDL-16455; meta-Terfenadine carboxylate	Drug Metabolite	Inflammation/Immunology
meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .

HY-13693

Mometasone furoate 2 Publications Verification Sch32088	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology Cancer
Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo

HY-N0575R

Pinocembrin (Standard)	Bacterial Reactive Oxygen Species Autophagy	Infection Inflammation/Immunology Cancer
Pinocembrin (Standard) is the analytical standard of Pinocembrin. This product is intended for research and analytical applications. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties .

HY-116609

C6 L-threo Ceramide	Interleukin Related	Inflammation/Immunology
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides . C6 L-threo Ceramide significantly inhibits IL-4 production in T cells. Anti-allergic agents .

HY-B0801AS

Fexofenadine-d10 hydrochloride MDL-16455-d₁₀ hydrochloride; Terfenadine carboxylate-d₁₀ hydrochloride	Isotope-Labeled Compounds Histamine Receptor	Inflammation/Immunology Endocrinology
Fexofenadine-d₁₀ (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years)[1].

HY-119832

Setastine EGIS-2062 free acid; EGYT-2062 free acid	Histamine Receptor	Inflammation/Immunology
Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting **anti-allergic agent. Setastine possesses potent histamine Hi-receptor** blocking properties and can be used for allergies and rhinitis research ^[1]<.

HY-100657S

Meta-Fexofenadine-d6 meta-MDL-16455-d₆; meta-Terfenadine carboxylate-d₆	Isotope-Labeled Compounds	Inflammation/Immunology
Meta-Fexofenadine-d₆ is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].

HY-100657R

meta-Fexofenadine (Standard)	Drug Metabolite	Inflammation/Immunology
meta-Fexofenadine (Standard) is the analytical standard of meta-Fexofenadine. This product is intended for research and analytical applications. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .

HY-N0201

Atractylenolide I 3 Publications Verification	TNF Receptor Toll-like Receptor (TLR) JAK STAT	Cancer
Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

HY-N3007A

(E)-Naringenin chalcone	Others	Inflammation/Immunology
(E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell .

HY-13693R

Mometasone furoate (Standard) 2 Publications Verification Sch32088 (Standard)	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology Cancer
Mometasone furoate (Standard) is the analytical standard of Mometasone furoate. This product is intended for research and analytical applications. Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo

HY-108259

HQL-79	PGE synthase	Inflammation/Immunology
HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD₂, and acts as an anti-allergic agent, with a K_d of 0.8 μM and an IC₅₀ of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .

HY-17002

Suplatast (Tosilate) 1 Publications Verification IPD 1151T	Interleukin Related	Inflammation/Immunology
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity .

HY-137941

Roxatidine	Histamine Receptor Caspase NF-κB p38 MAPK	Inflammation/Immunology
Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is an orally active histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect. Roxatidine is promising for research of gastric and duodenal ulcers .

HY-137941R

Roxatidine (Standard)	Histamine Receptor	Inflammation/Immunology
Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect .

HY-N12708

23-O-β-D-Glucopyranosyl-20-isoveratramine	Others	Others
23-O-β-D-Glucopyranosyl-20-isoveratramine is a potential anti-allergic agent extracted from nettles. A variety of COX-1, COX-2, 5-lipoxygenase and trypsin-like inhibitors and H1 antagonists are found in nettle extract, which can inhibit seasonal allergies, allergic rhinitis and other inflammatory diseases. and preventive effects .

HY-N0631

Cornuside 3 Publications Verification	p38 MAPK NF-κB	Inflammation/Immunology
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-N0201R

Atractylenolide I (Standard)	TNF Receptor Toll-like Receptor (TLR) JAK STAT	Cancer
Atractylenolide I (Standard) is the analytical standard of Atractylenolide I. This product is intended for research and analytical applications. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

HY-N0631R

Cornuside (Standard)	p38 MAPK NF-κB	Inflammation/Immunology
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-B0538A

Pemirolast potassium TWT-8152; BMY 26517	Histamine Receptor	Inflammation/Immunology Endocrinology
Pemirolast potassium (TWT-8152) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.

HY-U00168

KP136 AL136	Histamine Receptor	Inflammation/Immunology Endocrinology
KP136 (AL136) is an orally effective antiallergic agent. The IC₅₀ is 76.1 μg/mL for histamine release and 63 ug/mL for degranulation .

HY-137863

Pemirolast	Others	Inflammation/Immunology
Pemirolast is an orally active antiallergic agent. Pemirolast attenuates paclitaxel hypersensitivity reactions, can be used for bronchial asthma and conjunctivitis research ^- .

HY-106076

REV 2871 Eclazolast; CHBZ	Histamine Receptor	Inflammation/Immunology
REV 2871 (Eclazolast; CHBZ) is a potent and oral activity antiallergic agent. REV 2871 also is an irreversibility histamine release (HR) inhibitor .

HY-B0320A

Cromolyn sodium 4 Publications Verification Disodium Cromoglycate; FPL-670	Calcium Channel GSK-3	Inflammation/Immunology
Cromolyn sodium (Disodium Cromoglycate; FPL-670) is an antiallergic agent. Cromolyn sodium is a GSK-3β inhibitor with an IC₅₀ of 2.0 μM.

HY-U00133

HSR6071	Others	Inflammation/Immunology
HSR6071, a pyrazinecarboxamide derivative, is an orally active and potent antiallergic agent. HSR6071 potently inhibits the experimental asthma in rat models .

HY-106645

Cloxacepride	Calmodulin	Neurological Disease Inflammation/Immunology
Cloxacepride is an orally active and potent antiallergic agent. Cloxacepride is a CaM (calmodulin) antagonist. Cloxacepride has anti-PCA (passive cutaneous anaphylaxis) activity .

HY-13405

Tiaramide hydrochloride RHC 2592-A	Histamine Receptor	Inflammation/Immunology
Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release .

HY-N3007

Naringenin chalcone 2 Publications Verification	Others	Inflammation/Immunology
Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone is an orally active anti-inflammatory and antiallergic agent .

HY-13218

Acitazanolast WP-871	Histamine Receptor	Inflammation/Immunology
Acitazanolast is an orally active antiallergic agent, can inhibit histamine release. Acitazanolast can be used in study of type I anaphylaxis (immediate) caused by IgE antibodies .

HY-B0320AR

Cromolyn (sodium) (Standard) Disodium Cromoglycate (Standard); FPL-670 (Standard)	Calcium Channel GSK-3	Inflammation/Immunology
Cromolyn (sodium) (Standard) is the analytical standard of Cromolyn (sodium). This product is intended for research and analytical applications. Cromolyn sodium (Disodium Cromoglycate; FPL-670) is an antiallergic agent. Cromolyn sodium is a GSK-3β inhibitor with an IC₅₀ of 2.0 μM.

HY-123432

AHR-13268D	Histamine Receptor	Inflammation/Immunology
AHR-13268D is an oral active antiallergic and antihistaminic agent, with bioavailable approximately 88%. AHR-13268D is a potent inhibitor of histamine release from rat peritoneal mast cells, with the IC₅₀ of 0.51 nM .

HY-114538

Asobamast	TNF Receptor	Cardiovascular Disease Inflammation/Immunology
Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED₅₀=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments .

HY-B0970

Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor	Neurological Disease Endocrinology
Diphenylpyraline hydrochloride is a potent histamine H₁?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.

HY-107431

Diphenylpyraline	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline is a potent histamine H₁ receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-114724

HSR-609	Histamine Receptor	Inflammation/Immunology
HSR-609 is an orally active amphoteric antiallergic agent. HSR-609 has a high affinity for histamine H1-receptor in the guinea pig cerebral cortex. HSR-609 inhibits allergic airway hyperresponsiveness to Acetylcholine. HSR-609 shows poor ability to penetrate into the CNS in mice and guinea pigs .

HY-107431R

Diphenylpyraline (Standard)	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline (Standard) is the analytical standard of Diphenylpyraline. This product is intended for research and analytical applications. Diphenylpyraline is a potent histamine H1?receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-158316

BTL-MK	Others	Others
BTL-MK (Compound 19) an orally active antiallergic agent, that inhibits degranulation of mast cells with an IC₅₀ of 6.7 μM, through binding to the inhibitory receptor FcγRIIB. BTL-MK improves the metaboilic stability in human liver microsomes. BTL-MK ameliorates the allergic response in Ovalbumins (HY-W250978)-induced food allergy mice model. BTL-MK exhibits a good pharmacokinetic character with metabolic stability .

Cat. No.	Product Name	Category	Target	Chemical Structure