Tiaramide hydrochloride (Synonyms: RHC 2592-A)

Cat. No.: HY-13405 Purity: 98.70%: FAQs
Data Sheet SDS COA Handling Instructions

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Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release.

For research use only. We do not sell to patients.

Tiaramide hydrochloride Chemical Structure

CAS No. : 35941-71-0

Size	Price	Stock	Quantity
1 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Description

Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release^[1]^[2].

Molecular Weight

392.30

Formula

C₁₅H₁₉Cl₂N₃O₃S

CAS No.

35941-71-0

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1SC2=CC=C(Cl)C=C2N1CC(N3CCN(CCO)CC3)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (318.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5491 mL	12.7453 mL	25.4907 mL
5 mM	0.5098 mL	2.5491 mL	5.0981 mL
10 mM	0.2549 mL	1.2745 mL	2.5491 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.70%

Select Batch:

Data Sheet (270 KB) SDS (476 KB)

COA (252 KB) HNMR (262 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Khandwala A, et al. Antiallergic activity of tiaramide (RHC 2592-A). Int Arch Allergy Appl Immunol. 1982;69(2):159-68. [Content Brief]

[2]. Noguchi H, et al. Disposition and metabolic fate of tiaramide hydrochloride, a new anti-inflammatory agent, in the rat. Xenobiotica. 1977 Aug;7(8):491-503. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5491 mL	12.7453 mL	25.4907 mL	63.7267 mL
	5 mM	0.5098 mL	2.5491 mL	5.0981 mL	12.7453 mL
	10 mM	0.2549 mL	1.2745 mL	2.5491 mL	6.3727 mL
	15 mM	0.1699 mL	0.8497 mL	1.6994 mL	4.2484 mL
	20 mM	0.1275 mL	0.6373 mL	1.2745 mL	3.1863 mL
	25 mM	0.1020 mL	0.5098 mL	1.0196 mL	2.5491 mL
	30 mM	0.0850 mL	0.4248 mL	0.8497 mL	2.1242 mL
	40 mM	0.0637 mL	0.3186 mL	0.6373 mL	1.5932 mL
	50 mM	0.0510 mL	0.2549 mL	0.5098 mL	1.2745 mL
	60 mM	0.0425 mL	0.2124 mL	0.4248 mL	1.0621 mL
	80 mM	0.0319 mL	0.1593 mL	0.3186 mL	0.7966 mL
	100 mM	0.0255 mL	0.1275 mL	0.2549 mL	0.6373 mL

Tiaramide hydrochloride Related Classifications

Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tiaramide35941-71-0RHC 2592-AOthersanalgesicantiallergicnon-steroidalanti-inflammatoryInhibitorinhibitorinhibit

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