Search Result

Results for "

antioxidant effect

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Adrenergic Receptor (1) Akt (2) Amyloid-β (4) Apoptosis (20) Autophagy (2) Bacterial (7) Bcl-2 Family (1) Beta-secretase (3) Biochemical Assay Reagents (2) Calcium Channel (3) CDK (1) Cholinesterase (ChE) (5) COX (1) Drug Metabolite (2) Endogenous Metabolite (11) Ferroptosis (1) Fungal (3) GLP Receptor (1) Glucosidase (1) GSK-3 (1) HIF/HIF Prolyl-Hydroxylase (2) HSV (2) iGluR (1) Influenza Virus (3) Insulin Receptor (1) Isotope-Labeled Compounds (2) Keap1-Nrf2 (5) Leukotriene Receptor (8) Lipoxygenase (1) MAP3K (1) MDM-2/p53 (1) Melanocortin Receptor (1) Mitochondrial Metabolism (2) MMP (1) Monoamine Oxidase (2) Necroptosis (2) NF-κB (8) NO Synthase (7) p38 MAPK (3) Parasite (1) Phosphatase (1) Potassium Channel (1) PPAR (1) Proton Pump (2) Reactive Oxygen Species (20) ROS Kinase (1) Thrombin (1) Topoisomerase (1) Tyrosinase (3) VSV (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (29) Cardiovascular Disease (9) Endocrinology (6) Infection (11) Inflammation/Immunology (38) Metabolic Disease (19) Neurological Disease (33)

By Targets:

Acyltransferase (1)

Adrenergic Receptor (1)

Akt (2)

Amyloid-β (4)

Apoptosis (20)

Autophagy (2)

Bacterial (7)

Bcl-2 Family (1)

Beta-secretase (3)

Biochemical Assay Reagents (2)

Calcium Channel (3)

CDK (1)

Cholinesterase (ChE) (5)

COX (1)

Drug Metabolite (2)

Endogenous Metabolite (11)

Ferroptosis (1)

Fungal (3)

GLP Receptor (1)

Glucosidase (1)

GSK-3 (1)

HIF/HIF Prolyl-Hydroxylase (2)

HSV (2)

iGluR (1)

Influenza Virus (3)

Insulin Receptor (1)

Isotope-Labeled Compounds (2)

Keap1-Nrf2 (5)

Leukotriene Receptor (8)

Lipoxygenase (1)

MAP3K (1)

MDM-2/p53 (1)

Melanocortin Receptor (1)

Mitochondrial Metabolism (2)

MMP (1)

Monoamine Oxidase (2)

Necroptosis (2)

NF-κB (8)

NO Synthase (7)

p38 MAPK (3)

Parasite (1)

Phosphatase (1)

Potassium Channel (1)

PPAR (1)

Proton Pump (2)

Reactive Oxygen Species (20)

ROS Kinase (1)

Thrombin (1)

Topoisomerase (1)

Tyrosinase (3)

VSV (2)

Xanthine Oxidase (1)

By Research Areas:

Cancer (29)

Cardiovascular Disease (9)

Endocrinology (6)

Infection (11)

Inflammation/Immunology (38)

Metabolic Disease (19)

Neurological Disease (33)

104

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5092

7-Methylcoumarin	Others	Metabolic Disease
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-Z0548

Methyl 3,4-dihydroxybenzoate Protocatechuic acid methyl ester; Methyl protocatechuate	Keap1-Nrf2 Apoptosis	Inflammation/Immunology Cancer
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect .

HY-N5092R

7-Methylcoumarin (Standard)	Others	Metabolic Disease
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-122311

Orniplabin SMTP-7	Reactive Oxygen Species	Neurological Disease Inflammation/Immunology
Orniplabin (SMTP-7) is a low-molecular-weight compound that enhances plasminogen–fibrin binding, urokinase-catalyzed activation of plasminogen, and urokinase and plasminogen-mediated fibrin degradation. Orniplabin shows potential thrombolytic and anti-inflammatory effects. Orniplabin inhibits ROS .

HY-145888

Antioxidant agent-2	Amyloid-β	Neurological Disease
Antioxidant agent-2 (comp 3c), an BBB-penetrated antioxidant agent and a selective metal ions chelator, presents good neuroprotective effect and hepatoprotective effect for the study of Alzheimer’s disease .

HY-P0100

AHK	Reactive Oxygen Species	Inflammation/Immunology
AHK is a bioactive peptide with *antioxidant* effect and has been reported used as a cosmetic ingredient .

HY-Z0548S1

Methyl 3,4-dihydroxybenzoate-d3-1	Isotope-Labeled Compounds Keap1-Nrf2 Apoptosis	Inflammation/Immunology Cancer
Methyl 3,4-dihydroxybenzoate-d₃-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

HY-N9370

Isobellidifolin	Fungal	Infection
Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect .

HY-N9595

Bracteatin	Others	Inflammation/Immunology
Bracteatin is a natural product that can be isolated from Actinidia arguta. Bracteatin has antioxidant effect. .

HY-106514

Prifelone R 830; R 830T; S 16820	COX	Inflammation/Immunology
Prifelone (R 830; R 830T; S 16820) is a di-tert-butylphenol with anti-inflammatory and antioxidant activity. Prifelone inhibits guinea pig lung oxygenase and bovine seminal vesicle cyclooxygenase .

HY-N12785

1-Methoxy-2,3-methylenedioxyxanthone	Others	Cardiovascular Disease
Methoxy-2,3-methylenedioxyxanthone (Compound 5) is a xanthone that can be isolated from the roots of Polygala caudata. Methoxy-2,3-methylenedioxyxanthone has antioxidant and vasodilatory effects .

HY-N1449

Neonuezhenide	Others	Others
Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals .

HY-P5248

Tetrapeptide-1	Melanocortin Receptor	Metabolic Disease
Tetrapeptide-1 is a bioactive peptide with antioxidant effect and has been reported used as a cosmetic ingredient .

HY-159062

Goji Extract	Biochemical Assay Reagents NO Synthase	Neurological Disease
Goji Extract is a natural product with anti-aging, antioxidant, and neuroprotective effects. The antioxidant effect of Goji Extract has a positive impact on erectile dysfunction and can be used in research to improve erectile function .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-101445

Trolox 15+ Cited Publications	Reactive Oxygen Species Ferroptosis Apoptosis	Cancer
Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage .

HY-N0499A

Cyanidin	Others	Inflammation/Immunology
Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .

HY-N6669

Methyl 3-O-methylgallate 1 Publications Verification M3OMG	Others	Neurological Disease
Methyl 3-O-methylgallate (M3OMG) possesses antioxidant effect and can protect neuronal cells from oxidative damage .

HY-N4246

Bacopaside I	Others	Neurological Disease
Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .

HY-N1414

(E)-3',6-Disinapoylsucrose	Others	Neurological Disease
(E)-3',6-Disinapoylsucrose, the index component of Yuanzhi (Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect .

HY-N2267

(+)-Schisandrin B	Reactive Oxygen Species	Inflammation/Immunology
(+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart .

HY-N3102

p-Coumaryl alcohol p-Hydroxycinnamyl alcohol	Others	Others
p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. p-Coumaryl alcohol has inhibitory effect during the autoxidation of methyl linoleate .

HY-156032

PIMPC	GSK-3	Neurological Disease
PIMPC is a compound with antioxidant and metal-chelating properties. PIMPC is a novel inhibitor of glycogen synthase kinase 3 (GSK-3). PIMPC has potential anti-Alzheimer's disease effect .

HY-113314

AFMK	Endogenous Metabolite	Cancer
AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pK_a of AFMK at physiological pH is 8.7. Antioxidant capacity . AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway .

HY-Y1314

Dimethyl sulfone 1 Publications Verification	Drug Metabolite Endogenous Metabolite	Metabolic Disease
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-Y1314R

Dimethyl sulfone (Standard)	Drug Metabolite Endogenous Metabolite	Metabolic Disease
Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-167664

KY-455	Acyltransferase	Metabolic Disease
KY-455 is a novel inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). KY-455 inhibita rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC₅₀ values of 0.4, 0.9, 2.9 and 4.1 μmol/L, respectively.

HY-N1438

Hydroxygenkwanin 7-O-Methylluteolin	Others	Cancer
Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect .

HY-W130442

N-Isopropyl-N'-phenyl-p-phenylenediamine	Others	Inflammation/Immunology
N-Isopropyl-N'-phenyl-p-phenylenediamine is an antioxidant used in rubber manufacturing to reduce the detrimental effect of oxygen. N-Isopropyl-N'-phenyl-p-phenylenediamine can cause contact allergy .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Endogenous Metabolite	Neurological Disease
β-Cryptoxanthin ((3R)-β-Cryptoxanthin), isolated from tangerines, red peppers, and pumpkin, is an oxygenated carotenoid and a potent antioxidant. β-Cryptoxanthin has an anti-stress effect .

HY-107805

Dihydroactinidiolide	Others	Infection Neurological Disease Cancer
Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect .

HY-162165

Neuroprotective agent 4	Others	Neurological Disease
Neuroprotective agent 4 (compound 24a) is a novel and effective small molecule antioxidant. Neuroprotective agent 4 has a neuroprotective effect. Neuroprotective agent 4 can be used in the study of ischemic stroke and related diseases .

HY-P2920

Protamine from salmon	Biochemical Assay Reagents Thrombin Bacterial	Infection Cardiovascular Disease
Protamine from salmon is a biochemical agent with antioxidant, antiheparin and antimicrobial activities. Protamine from salmon neutralizes the anticoagulant effect of heparin, thereby preventing the formation of antithrombin complexes in canine samples pretreated with heparin in vitro .

HY-Y0892

4-Hydroxybenzyl alcohol 1 Publications Verification	Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth .

HY-N0427

Phellodendrine	Akt NF-κB	Inflammation/Immunology
Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendron amurense. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect .

HY-N7031

(±)-Vasicine (±)-Peganine	Proton Pump	Inflammation/Immunology
(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H ⁺-K ⁺-ATPase activity?in vitro?with an IC₅₀ of 73.47?μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and?cytoprotective?effect .

HY-N1782

3,4-O-Isopropylidene-shikimic acid	Others	Inflammation/Immunology
3,4-O-Isopropylidene-shikimicn acid is a natural product that can be isolated from the whole plants of Hypericum wightianum. 3,4-O-Isopropylidene-shikimic acid has anti-inflammatory effect and antioxidant activities .

HY-112554

PDM11	Others	Others
PDM11 is a derivative of antioxidant resveratrol. PDM11 do not exhibit any significant protective effect against oxidation of linoleate micelles initiated by radiolysis-generated hydroxyl radicals. PDM11 is inactive in resveratrol activity assays .

HY-N4246R

Bacopaside I (Standard)	Others	Neurological Disease
Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .

HY-152506

Antioxidant agent-8	Amyloid-β	Neurological Disease
Antioxidant agent-8 is an orally active inhibitor of Aβ_1-42 deposition. Antioxidant agent-8 inhibits fibril aggregation (IC₅₀=11.15 µM) and promotes fibril disaggregation (IC₅₀=6.87 µM). Antioxidant agent-8 also inhibits Cu ²⁺-induced Aβ_1-42 fibril aggregation (IC₅₀=3.69 µM) and promotes Cu ²⁺-induced Aβ_1-42 fibril disaggregation (IC₅₀=3.35 µM). Antioxidant agent-8 has antioxidant activity, anti-inflammatory activity, biosafety, blood-brain barrier permeability and neuroprotective effect .

HY-N1994

Swertianine	Others	Inflammation/Immunology
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .

HY-N9536

Cinnamtannin A2	GLP Receptor	Metabolic Disease
Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect .

HY-B1041

Aminoguanidine hydrochloride 4 Publications Verification Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride	NO Synthase Apoptosis	Endocrinology
Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research .

HY-149820

MAO-B-IN-22	Monoamine Oxidase	Neurological Disease
MAO-B-IN-22 (compound 6h) is a potent MAO-B inhibitor with an IC₅₀ of 0.014 μM. MAO-B-IN-22 has high antioxidant activity, good metal chelating ability, proper BBB permeability and significant neuroprotective effect .

HY-B1041A

Aminoguanidine Pimagedine; GER-11(free base) ; Aminoguanidinium	NO Synthase Apoptosis	Endocrinology
Aminoguanidine (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine has antioxidant properties. Aminoguanidine can be used in diabetic nephropathy research .

HY-N1438R

Hydroxygenkwanin (Standard)	Others	Cancer
Hydroxygenkwanin (Standard) is the analytical standard of Hydroxygenkwanin. This product is intended for research and analytical applications. Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect .

HY-W709349

Flupirtine hydrochloride D 9998 hydrochloride	Potassium Channel iGluR	Inflammation/Immunology
Flupirtine hydrochloride (D 9998 hydrochloride) is a selective neuropotassium channel opener with analgesic activity. Flupirtine hydrochloride is used to inhibit a variety of pain conditions, including chronic musculoskeletal pain, migraines, and neuralgia. Flupirtine hydrochloride has antidepressant and antioxidant properties and may increase the analgesic effect in combination therapy with morphine. Flupirtine hydrochloride relieves abnormally increased muscle tension and has a muscle relaxant effect. Flupirtine hydrochloride is clinically superior to other drugs, such as tramadol and pantoxan, plus its side effects are better tolerated. Flupirtine hydrochloride has a significant effect on inhibiting neural hyperexcitability and therefore exhibits inhibitory potential in various pain states .

HY-N1780

3,4-Dimethoxyphenol	Tyrosinase	Metabolic Disease Endocrinology
3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity . 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth .

HY-N8015

Octanal	Endogenous Metabolite Bacterial Fungal	Infection Cancer
Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC₅₀ value of 3.5 μg/mL .

HY-W278582

Topoisomerase II inhibitor 14	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO .

Cat. No.	Product Name

HY-L065

Traditional Chinese Medicine Active Compound Library

2,918 compounds

Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.

MCE designs a unique collection of 2,918 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

Cat. No.	Product Name	Type

HY-159062

Goji Extract	Carbohydrates
Goji Extract is a natural product with anti-aging, antioxidant, and neuroprotective effects. The antioxidant effect of Goji Extract has a positive impact on erectile dysfunction and can be used in research to improve erectile function .

HY-P1956

Human serum albumin

1 Publications Verification

HSA

Native Proteins

Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-P1956A

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)

HSA (Cell culture grade, Endotoxin<0.125 EU/mg)

Native Proteins

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-P2920

Protamine from salmon	Cell Assay Reagents
Protamine from salmon is a biochemical agent with antioxidant, antiheparin and antimicrobial activities. Protamine from salmon neutralizes the anticoagulant effect of heparin, thereby preventing the formation of antithrombin complexes in canine samples pretreated with heparin in vitro .

Cat. No.	Product Name	Target	Research Area

HY-P5248

Tetrapeptide-1	Melanocortin Receptor	Metabolic Disease
Tetrapeptide-1 is a bioactive peptide with antioxidant effect and has been reported used as a cosmetic ingredient .

HY-119152

CMX-2043	Insulin Receptor Tyrosinase Akt	Others
CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model .

HY-P0100

AHK	Reactive Oxygen Species	Inflammation/Immunology
AHK is a bioactive peptide with *antioxidant* effect and has been reported used as a cosmetic ingredient .

HY-W013494R

L-Carnosine (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging . L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .

HY-P5557

TP4 (Nile tilapia piscidin)	Bacterial Necroptosis	Cancer
TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide. TP4 inhibits multiple gram positive and negative strains (MIC: 0.03-10 μg/mL). TP4 shows hemolytic activities. TP4 enhances immune response, antioxidant activity, and intestinal health against bacterial infections. TP4 also has anti-tumor effect, and induces necrosis by triggering mitochondrial dysfunction in cancer cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5092

7-Methylcoumarin	Microorganisms Source classification Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields	Others
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-Z0548

Methyl 3,4-dihydroxybenzoate Protocatechuic acid methyl ester; Methyl protocatechuate	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Inflammation/Immunology Disease Research Fields Theaceae	Keap1-Nrf2 Apoptosis
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect .

HY-N1449

Neonuezhenide	Structural Classification Oleaceae Classification of Application Fields Ligustrum lucidum Ait. Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals .

HY-N6669

Methyl 3-O-methylgallate 1 Publications Verification M3OMG	Sanguisorba officinalis Linn. Source classification Rosaceae Phenols Polyphenols Plants	Others
Methyl 3-O-methylgallate (M3OMG) possesses antioxidant effect and can protect neuronal cells from oxidative damage .

HY-N5092R

7-Methylcoumarin (Standard)	Microorganisms Source classification Coumarins Phenylpropanoids	Others
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N9370

Isobellidifolin	Infection other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields	Fungal
Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect .

HY-N9595

Bracteatin	Structural Classification Funariaceae Source classification Funaria hygrometrica Hedw. Phenols Polyphenols Plants	Others
Bracteatin is a natural product that can be isolated from Actinidia arguta. Bracteatin has antioxidant effect. .

HY-N12785

1-Methoxy-2,3-methylenedioxyxanthone	Structural Classification Natural Products Source classification Polygalaceae Plants Polygala caudata Rehder & E. H. Wilson	Others
Methoxy-2,3-methylenedioxyxanthone (Compound 5) is a xanthone that can be isolated from the roots of Polygala caudata. Methoxy-2,3-methylenedioxyxanthone has antioxidant and vasodilatory effects .

HY-N10020

Patulitrin	Structural Classification Flavonols Flavonoids Ohwia caudata (Thunberg) H. Ohashi Source classification Plants Compositae	Lipoxygenase
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-N0499A

Cyanidin	Structural Classification Caprifoliaceae Source classification Phenols Polyphenols Sambucus williamsii Hance Plants	Others
Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .

HY-N4246

Bacopaside I	Triterpenes Structural Classification Terpenoids Source classification Scrophulariaceae Plants Bacopa monnieri (Linn.) Wettst.	Others
Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .

HY-N1414

(E)-3',6-Disinapoylsucrose	Structural Classification Simple Phenylpropanols Source classification Polygalaceae Phenols Polyphenols Phenylpropanoids Plants Polygala tenuifolia Willd.	Others
(E)-3',6-Disinapoylsucrose, the index component of Yuanzhi (Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect .

HY-N2267

(+)-Schisandrin B	Structural Classification Natural Products Classification of Application Fields Source classification Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
(+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart .

HY-N3102

p-Coumaryl alcohol p-Hydroxycinnamyl alcohol	Structural Classification Simple Phenylpropanols Source classification Alpinia officinarum Hance Phenylpropanoids Plants Zingiberaceae	Others
p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. p-Coumaryl alcohol has inhibitory effect during the autoxidation of methyl linoleate .

HY-113314

AFMK	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pK_a of AFMK at physiological pH is 8.7. Antioxidant capacity . AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway .

HY-Y1314

Dimethyl sulfone 1 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-Y1314R

Dimethyl sulfone (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Drug Metabolite Endogenous Metabolite
Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-N1438

Hydroxygenkwanin 7-O-Methylluteolin	Structural Classification Flavonoids Classification of Application Fields Flavones Thymelaeaceae Source classification Phenols Polyphenols Plants Daphne genkwa Sieb. et Zucc. Disease Research Fields Cancer	Others
Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Other Terpenoids Structural Classification Capsicum annuum L. other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Solanaceae Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Cryptoxanthin ((3R)-β-Cryptoxanthin), isolated from tangerines, red peppers, and pumpkin, is an oxygenated carotenoid and a potent antioxidant. β-Cryptoxanthin has an anti-stress effect .

HY-107805

Dihydroactinidiolide	Infection Microorganisms Iridoids Classification of Application Fields Neurological Disease Zantedeschia aethiopica (Linn.) Spreng. Araceae Terpenoids Source classification Plants Disease Research Fields	Others
Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect .

HY-Y0892

4-Hydroxybenzyl alcohol 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Microorganisms Gastrodia elata Bl. Orchidaceae Phenols Inflammation/Immunology Disease Research Fields	Apoptosis Endogenous Metabolite
4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth .

HY-N0427

Phellodendrine	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Source classification Rutaceae Phenols Polyphenols Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields	Akt NF-κB
Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendron amurense. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect .

HY-N7031

(±)-Vasicine (±)-Peganine	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Zygophyllaceae Peganum harmala Linn. Source classification Plants Inflammation/Immunology Disease Research Fields	Proton Pump
(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H ⁺-K ⁺-ATPase activity?in vitro?with an IC₅₀ of 73.47?μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and?cytoprotective?effect .

HY-N1782

3,4-O-Isopropylidene-shikimic acid	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Inflammation/Immunology Disease Research Fields	Others
3,4-O-Isopropylidene-shikimicn acid is a natural product that can be isolated from the whole plants of Hypericum wightianum. 3,4-O-Isopropylidene-shikimic acid has anti-inflammatory effect and antioxidant activities .

HY-N4246R

Bacopaside I (Standard)	Triterpenes Structural Classification Terpenoids Source classification Scrophulariaceae Plants Bacopa monnieri (Linn.) Wettst.	Others
Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .

HY-N1994

Swertianine	Structural Classification Flavonoids Xanthones Flavones Source classification Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Phenols Plants	Others
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .

HY-N9536

Cinnamtannin A2	Structural Classification Cinnamomum cassia (L.) D. Don Classification of Application Fields Source classification Metabolic Disease Plants Flavanonols Flavonoids Phenols Polyphenols Lauraceae Biflavones Disease Research Fields	GLP Receptor
Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect .

HY-N1438R

Hydroxygenkwanin (Standard)	Structural Classification Flavonoids Flavones Thymelaeaceae Source classification Phenols Polyphenols Plants Daphne genkwa Sieb. et Zucc.	Others
Hydroxygenkwanin (Standard) is the analytical standard of Hydroxygenkwanin. This product is intended for research and analytical applications. Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect .

HY-N1780

3,4-Dimethoxyphenol	Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Metabolic Disease Cosmetic Research Disease Research Fields	Tyrosinase
3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity . 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth .

HY-N8015

Octanal	Infection Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	Endogenous Metabolite Bacterial Fungal
Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC₅₀ value of 3.5 μg/mL .

HY-N11441

cis-Ferulic acid 4-O-β-D-glucopyranoside	Structural Classification Ketones, Aldehydes, Acids Zygophyllaceae Source classification Plants Nitraria sibirica Pall	Phosphatase
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-N7031R

(±)-Vasicine (Standard)	Alkaloids Structural Classification Other Alkaloids Zygophyllaceae Peganum harmala Linn. Source classification Plants	Proton Pump
(±)?-Vasicine (Standard) is the analytical standard of (±)?-Vasicine. This product is intended for research and analytical applications. (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H+-K+-ATPase activity in vitro with an IC₅₀ of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect .

HY-N6613

Polygalacturonic acid Galacturonic acid polymer	Infection Structural Classification Natural Products Polysaccharides Classification of Application Fields Malus pumila Mill. Rosaceae Plants Inflammation/Immunology Disease Research Fields Saccharides	Others
Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .

HY-N2011

Octyl gallate n-Octyl gallate; Stabilizer GA 8	Infection Structural Classification Paeonia lactiflora Pall. Classification of Application Fields Source classification Phenols Polyphenols Plants Paeoniaceae Disease Research Fields	VSV Bacterial HSV Influenza Virus Reactive Oxygen Species
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-N1414R

(E)-3',6-Disinapoylsucrose (Standard)	Structural Classification Simple Phenylpropanols Source classification Polygalaceae Phenols Polyphenols Phenylpropanoids Plants Polygala tenuifolia Willd.	Others
(E)-3',6-Disinapoylsucrose (Standard) is the analytical standard of (E)-3',6-Disinapoylsucrose. This product is intended for research and analytical applications. (E)-3',6-Disinapoylsucrose, the index component of Yuanzhi (Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect .

HY-Y0892R

4-Hydroxybenzyl alcohol (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Gastrodia elata Bl. Orchidaceae Source classification Phenols Plants Endogenous metabolite	Apoptosis Endogenous Metabolite
4-Hydroxybenzyl alcohol (Standard) is the analytical standard of 4-Hydroxybenzyl alcohol. This product is intended for research and analytical applications. 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth [4].

HY-W015229R

3-Indolepropionic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .

HY-N12586

Pheophytin a	Suaeda vermiculata Forssk. ex J.F.Gmel. Structural Classification Alkaloids Other Alkaloids Source classification Amaranthaceae Plants	Reactive Oxygen Species
Pheophytin a is a chlorophyll that can be isolated from S. vermiculata extracts. Pheophytin a has antioxidant activity with IC₅₀ values of? 200.5 and 137.7 μg/mL for SOD, and NO respectively. Pheophytin a has reducing power with an IC₅₀ value of 4.2 μg/mL . Pheophytin a has a cytotoxic effect on the MCF-7 cell line(IC₅₀= 35.9 μg/mL)^[1].

HY-N8015R

Octanal (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Source classification Plants	Endogenous Metabolite Bacterial Fungal
Octanal (Standard) is the analytical standard of Octanal. This product is intended for research and analytical applications. Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC₅₀ value of 3.5 μg/mL .

HY-N6642

Ankaflavin	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	PPAR Apoptosis
Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects .

HY-W013494R

L-Carnosine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging . L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .

HY-116807

Dihydrolipoic Acid DHLA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reactive Oxygen Species
Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical . Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression .

HY-167825

Barakol	Seeds of Cassia tora Linn. Structural Classification Natural Products Leguminosae Source classification Plants	MMP Apoptosis Bcl-2 Family Reactive Oxygen Species
Barakol is a major compound found in Cassia siamea. Barakol inhibits MMP-3 activity. Barakol potentiates the anti-metastatic effect of Doxorubicin (HY-15142). Barakol induces apoptosis, with ROS generation, increase in expression ratio of Bax/Bcl-2, and caspase-9 activation. Barakol has laxative, anxiolytic, CNS depressant, and antioxidant, anticancer effects .

HY-N2011R

Octyl gallate (Standard)	Structural Classification Paeonia lactiflora Pall. Source classification Phenols Polyphenols Plants Paeoniaceae	VSV Bacterial HSV Influenza Virus Reactive Oxygen Species
Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-N0408R

Picroside II (Standard)	Structural Classification Iridoids Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell	NF-κB Reactive Oxygen Species Apoptosis Influenza Virus
Picroside II (Standard) is the analytical standard of Picroside II. This product is intended for research and analytical applications. Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways . Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities .

HY-W016409

Ethyl 3,4-dihydroxybenzoate 1 Publications Verification Protocatechuic acid ethyl ester	Structural Classification Arachis hypogaea L. Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species NO Synthase Autophagy Apoptosis
Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a prolyl-hydroxylase inhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate protects myocardium by activating NO synthase and generating mitochondrial ROS. Ethyl 3,4-dihydroxybenzoate induces cell autophagy and apoptosis in ESCC cells. Ethyl 3,4-dihydroxybenzoate is a collagen synthesis inhibitor and has a bone protecting-effect .

HY-116807R

Dihydrolipoic Acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reactive Oxygen Species
Dihydrolipoic Acid (Standard) is the analytical standard of Dihydrolipoic Acid. This product is intended for research and analytical applications. Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical . Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression .

HY-N0226A

Epiberberine chloride 4 Publications Verification	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Coptis chinensis Franch. Ranunculaceae Source classification Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields	Cholinesterase (ChE) Beta-secretase Reactive Oxygen Species
Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC₅₀s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO ^- scavenging effect (IC₅₀, 16.83 μM), and may protect against Alzheimer disease . Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways . Epiberberine has the potential effect in the research of diabetic disease .

HY-N8788

Baicalein 7-O-β-D-ethylglucuronide	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells .

HY-W016409R

Ethyl 3,4-dihydroxybenzoate (Standard)	Structural Classification Arachis hypogaea L. Leguminosae Source classification Phenols Polyphenols Plants	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species NO Synthase Autophagy Apoptosis
Ethyl 3,4-dihydroxybenzoate (Standard) is the analytical standard of Ethyl 3,4-dihydroxybenzoate. This product is intended for research and analytical applications. Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a prolyl-hydroxylase inhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate protects myocardium by activating NO synthase and generating mitochondrial ROS. Ethyl 3,4-dihydroxybenzoate induces cell autophagy and apoptosis in ESCC cells. Ethyl 3,4-dihydroxybenzoate is a collagen synthesis inhibitor and has a bone protecting-effect [4].

Cat. No.	Product Name	Chemical Structure

HY-Z0548S1

Methyl 3,4-dihydroxybenzoate-d3-1
Methyl 3,4-dihydroxybenzoate-d₃-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

HY-13315S1

Montelukast-d6 sodium
Montelukast-d₆ (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].

HY-13315S

Montelukast-d6
Montelukast-d₆ is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].

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