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circumvent thiol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Picoplatin AMD473; ZD0473	DNA/RNA Synthesis	Cancer
Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA .

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