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Picoplatin  (Synonyms: AMD473; ZD0473)

Cat. No.: HY-131468 Purity: 98.5%
COA Handling Instructions

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Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA.

For research use only. We do not sell to patients.

Picoplatin Chemical Structure

Picoplatin Chemical Structure

CAS No. : 181630-15-9

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Description

Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA[1].

Molecular Weight

376.15

Formula

C6H10Cl2N2Pt
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

[Cl-][Pt+2]([N]1=C(C)C=CC=C1)([NH3])[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 98.5%

COA (249 KB)

Handling Instructions (2659 KB)
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Picoplatin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Picoplatin181630-15-9AMD473 ZD0473AMD 473AMD-473ZD0473ZD 0473ZD-0473OthersPlatinumantineoplasticcircumvent thioldrug resistanceglutathioneGSHDNAInhibitorinhibitorinhibit

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