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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

corneal endothelial cells

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13813
    Blebbistatin
    20+ Cited Publications

    		 Myosin Others
    Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration .
    Blebbistatin
  • HY-17495
    Carteolol

    OPC-1085

    		 Adrenergic Receptor Caspase Bcl-2 Family Neurological Disease
    Carteolol is a non-selective β-adrenoceptor antagonist. Carteolol induces apoptosis via a caspase activated and mitochondrial-dependent pathway. Carteolol can be used for glaucoma research .
    Carteolol
  • HY-116116
    Tafetinib

    SIM010603

    		 c-Kit RET VEGFR Cancer
    Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibitsstem cell factor receptor (Kit),vascular endothelial growth factor receptor-2 (VEGFR-2),platelet-derived growth factor receptor-β (PDGFR-β),glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), andFms-like tyrosine kinase-3 (FLT3)withIC50values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation ofPDGFR-βandVEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis .
    Tafetinib
  • HY-157666
    13:0 PC

    PC(13:0/13:0)

    		 Endogenous Metabolite Others
    13:0 PC (PC(13:0/13:0)), also known as ditridecanoyl phosphatidyl choline (DTPC), is a phospholipid characterized by its unique structure that includes a polar head with a positively charged quaternary amine and a negatively charged phosphate, along with two non-polar fatty acid tails. This composition allows 13:0 PC to function effectively as a surfactant in mucus, while its amphiphilic nature makes it an essential component of cell membranes, particularly in endothelial cells, corneal epithelial cells, and fibroblasts. The liver synthesizes 13:0 PC, and it is also found in dietary sources such as eggs and soybeans. In addition, Avanti offers a diverse range of phosphatidylcholine products, including 13:0 PC, which are meticulously purified by HPLC to maintain their stability against oxidation and hydrolysis.
    13:0 PC

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