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Results for "

fluorinated

" in MedChemExpress (MCE) Product Catalog:

36

Inhibitors & Agonists

1

Fluorescent Dye

5

Biochemical Assay Reagents

2

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0069
    Fludarabine
    Maximum Cited Publications
    68 Publications Verification

    F-ara-A; NSC 118218

    		 Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis Cancer
    Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
    Fludarabine
  • HY-32126
    1-Fluoronaphthalene

    		Drug Intermediate Others
    1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene
  • HY-124472
    2,4-Difluororesorcinol

    		Drug Intermediate Others
    2,4-Difluororesorcinol is a fluorinated building block .
    2,4-Difluororesorcinol
  • HY-40421
    (R)-3-Fluoropyrrolidine hydrochloride

    		Biochemical Assay Reagents Others
    (R)-3-Fluoropyrrolidine hydrochloride is a derivative of fluorinated pyrrolidines. The amide series of fluorinated pyrrolidines are inhibitors of dipeptidyl peptidase DP-IV. Novel α4β2 receptor ligands characterized by a 3-Fluoropyrrolidine core .
    (R)-3-Fluoropyrrolidine hydrochloride
  • HY-B0628
    Vinflunine

    		Microtubule/Tubulin Cancer
    Vinflunine is a type of fluorinated vinca alkaloid that has the ability to block mitosis and interact with tubulin .
    Vinflunine
  • HY-B0069R
    Fludarabine (Standard)

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis Cancer
    Fludarabine (Standard) is the analytical standard of Fludarabine. This product is intended for research and analytical applications. Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
    Fludarabine (Standard)
  • HY-32126R
    1-Fluoronaphthalene (Standard)

    		Adrenergic Receptor Serotonin Transporter Others
    1-Fluoronaphthalene (Standard) is the analytical standard of 1-Fluoronaphthalene. This product is intended for research and analytical applications. 1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene (Standard)
  • HY-158882
    FLAC6

    		Biochemical Assay Reagents Adenosine Receptor Others
    FLAC6 is a potent fluorinated detergent that can be used to solubilize membrane proteins (the native adenosine receptor A2AR, a G protein-coupled receptor, and two native transporters AcrB and BmrA). FLAC6 can maintain the structural and functional integrity of different membrane proteins .
    FLAC6
  • HY-W075766
    Nickel(II) fluoride

    Nickel difluoride

    		 Biochemical Assay Reagents Others
    Nickel(II) fluoride (Nickel difluoride) is a fluorinating agent and catalyst suitable for surface treatment of aluminum profiles and the production of inks, fluorescent lamps, and organic synthesis. Nickel(II) fluoride is a kind of biological materials or organic compounds that are widely used in life science research .
    Nickel(II) fluoride
  • HY-79171
    3,4-Difluorophenylalanine

    		Biochemical Assay Reagents Others
    3,4-Difluorophenylalanine is a fluorinated peptide with gelation ability .
    3,4-Difluorophenylalanine
  • HY-B0248
    Desonide
    2 Publications Verification

    		 Glucocorticoid Receptor Inflammation/Immunology Endocrinology
    Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on glucocorticoid receptors.
    Desonide
  • HY-B0248R
    Desonide (Standard)

    		Glucocorticoid Receptor Inflammation/Immunology Endocrinology
    Desonide (Standard) is the analytical standard of Desonide. This product is intended for research and analytical applications. Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on glucocorticoid receptors.
    Desonide (Standard)
  • HY-113938
    AZD4694

    NAV4694

    		 Amyloid-β Cardiovascular Disease
    AZD4694 (NAV4694), a fluorinated β-amyloid (Aβ) plaque neuroimaging PET radioligand, shows high affinity for Aβ fibrils (Kd = 2.3 nM) .
    AZD4694
  • HY-163474
    MAO-B-IN-32

    		Monoamine Oxidase Neurological Disease
    MAO-B-IN-32 is an inhibitor of MAO-B (IC50 = 16 nM).MAO-B-IN-32 increases dopamine concentration in the brain by inhibiting MAO-B activity .
    MAO-B-IN-32
  • HY-115859
    SCH 25393

    		Bacterial Infection
    SCH 25393 is a potent antibacterial agent .
    SCH 25393
  • HY-111343
    ONC212
    4 Publications Verification

    		 Apoptosis Endocrinology Cancer
    ONC212, a fluorinated-ONC201 analogue, is a promising anti-cancer agent and also a selective agonist of GPR132. ONC212 also induces apoptosis .
    ONC212
  • HY-155869
    5-fluoro-dCTP

    5-Fluoro-2′-deoxycytidine 5′-triphosphate

    		 DNA/RNA Synthesis Others
    5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
    5-fluoro-dCTP
  • HY-155869A
    5-fluoro-dCTP sodium

    5-Fluoro-2′-deoxycytidine 5′-triphosphate sodium

    		 DNA/RNA Synthesis Others
    5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
    5-fluoro-dCTP sodium
  • HY-W050049
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate

    		Biochemical Assay Reagents Others
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research .
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate
  • HY-113719
    VM4-037

    		Carbonic Anhydrase Cancer
    VM4-037 can be used for the synthesis of VM4-037(18F). VM4-037(18F) is a fluorinated PET imaging agent for carbonic anhydrase IX .
    VM4-037
  • HY-P2496
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled

    		Endothelin Receptor Cardiovascular Disease
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled
  • HY-162453
    Anticancer agent 204

    		Apoptosis MMP Cancer
    Anticancer agent 204 (Compound 6), a cinnamide fluorinated derivative, possesses anticancer activity. Anticancer agent 204 can arrest the cell cycle of HepG2 cells in the G1 phase and induce apoptosis by reducing the level of mitochondrial membrane polarization (MMP) .
    Anticancer agent 204
  • HY-139211
    Difluorinated Curcumin

    3,4-Difluorobenzylidene curcumin

    		 Reactive Oxygen Species Cancer
    Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy .
    Difluorinated Curcumin
  • HY-B0139
    Flucytosine
    2 Publications Verification

    5-Fluorocytosine; NSC 103805; Ro 2-9915

    		 Fungal Antibiotic Infection Cancer
    Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
    Flucytosine
  • HY-106218
    Flurocitabine

    5-Fluorocyclocytidine; 5'-Fluorocyclocytidine

    		 Nucleoside Antimetabolite/Analog Cancer
    Flurocitabine (5-Fluorocyclocytidine) is a fluorinated anlydride analog of cytosine arabinoside, partially hydrolysecl in vivo into two active antitumor substances (arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU)). Flurocitabine (5-Fluorocyclocytidine) has antitumor activity during phase I studies in acute leukemia and solid tumors .
    Flurocitabine
  • HY-136595
    3,5-Difluoro-L-tyrosine

    		Phosphatase Others
    3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) .
    3,5-Difluoro-L-tyrosine
  • HY-143330
    MAO-B-IN-4

    		Monoamine Oxidase Neurological Disease
    MAO-B-IN-4 (Compound 26) is an orally active and reversible MAO-B inhibitor with an IC50 of 9 nM. MAO-B-IN-4 has good metabolic stability, safety profile and brain permeability. MAO-B-IN-4 shows antidepressant activity in rats and mice. MAO-B-IN-4 can be used in studies related to Alzheimer's disease .
    MAO-B-IN-4
  • HY-W422400
    Fluoroglutamine (2S,4R)

    		Biochemical Assay Reagents Others Cancer
    Fluoroglutamine (2S,4R) is a fluorinated derivative of glutamine. As a substrate for various aminotransferases, Fluoroglutamine (2S,4R) can be used as a tracer for positron emission tomography (PET) imaging. Fluoroglutamine (2S,4R) is applied in the research fields of tumor metabolism and imaging .
    Fluoroglutamine (2S,4R)
  • HY-B0139R
    Flucytosine (Standard)

    5-Fluorocytosine (Standard); NSC 103805 (Standard); Ro 2-9915 (Standard)

    		 Fungal Antibiotic Infection Cancer
    Flucytosine (Standard) is the analytical standard of Flucytosine. This product is intended for research and analytical applications. Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
    Flucytosine (Standard)
  • HY-149558
    CXCR4-IN-2

    		Apoptosis CXCR Cancer
    CXCR4-IN-2 (compound A1) is a bifunctional fluorinated small molecule that is a potent CXCR4 inhibitor with anticancer activity. CXCR4-IN-2 has cytotoxic (IC50: 60 μg/mL; 72 h) and antiproliferative effects on mouse colorectal cancer (CRC) cells. CXCR4-IN-2 induces cell arrest in the G2/M phase and induces apoptosis .
    CXCR4-IN-2
  • HY-15234
    Fluticasone furoate

    		Glucocorticoid Receptor Inflammation/Immunology
    Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .
    Fluticasone furoate
  • HY-15234R
    Fluticasone furoate (Standard)

    		Glucocorticoid Receptor Inflammation/Immunology
    Fluticasone furoate (Standard) is the analytical standard of Fluticasone furoate. This product is intended for research and analytical applications. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .
    Fluticasone furoate (Standard)
  • HY-W095635
    Tetramethylammonium fluoride tetrahydrate

    		Biochemical Assay Reagents Others
    Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.
    Tetramethylammonium fluoride tetrahydrate
  • HY-164576
    NCS-MP-NODA

    NODA-Bz-SCN

    		 Radionuclide-Drug Conjugates (RDCs) Cancer
    NCS-MP-NODA (NODA-Bz-SCN) is a bifunctional chelator that can be used to bind to the labeled peptide DK222 with high specificity for PD-L1. The corresponding fluorinated radioactive is synthesized by the aluminum fluoride method, and NCS-MP-NODA targets DK222 to obtain the radioactive analog [18/19F]DK222. [18F]DK222 can quantify PD-L1 in vivo via PET tracking in xenograft models of multiple cancer types.
    NCS-MP-NODA
  • HY-D1447
    Fluo-3FF pentapotassium

    		Fluorescent Dye Others
    Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 碌M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
    Fluo-3FF pentapotassium
  • HY-W250129
    2,3,4,5-Tetrafluorobenzoyl chloride

    		Biochemical Assay Reagents Others
    2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.
    2,3,4,5-Tetrafluorobenzoyl chloride

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