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Results for "

free radical inhibition

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

8

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0704
    Azelaic acid
    1 Publications Verification

    Nonanedioic acid

    		 Antibiotic Endogenous Metabolite Inflammation/Immunology
    Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals .
    Azelaic acid
  • HY-N0499A
    Cyanidin

    		Others Inflammation/Immunology
    Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .
    Cyanidin
  • HY-N10295
    Flavipin

    		Aryl Hydrocarbon Receptor Inflammation/Immunology
    Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 + T cells and CD11b + macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA . Flavipin exhibits the DPPH free radical scavenging ability with IC50 value of 7.2 μM, and has potent α-glucosidase inhibition with IC50 value of 33.8 μM .
    Flavipin
  • HY-N7774
    Echinatine N-oxide

    		Others Others
    Echinatine N-oxide is a pyrrolizidine alkaloid found in R. graeca .
    Echinatine N-oxide
  • HY-N10294
    Epicoccone B

    		HIV Infection Inflammation/Immunology
    Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC50 value of 10.8 μM, and has potent α-glucosidase inhibition with IC50 value of 27.3 μM. Anti-HIV activity .
    Epicoccone B
  • HY-N1719
    Isoarjunolic acid

    2α,3α,23-Trihydroxyolean-12-en-28-oic acid

    		 Others Others
    Isoarjunolic acid (2α,3α,23-Trihydroxyolean-12-en-28-oic acid) is a triterpenoid, can be isolated from the stems of Cornus kousa. Isoarjunolic acid could have free radical scavenging activity and elastase inhibition activity .
    Isoarjunolic acid
  • HY-116866
    Sclerotiorin

    		Lipoxygenase Fungal Infection Inflammation/Immunology
    Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC50: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED50: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans .
    Sclerotiorin
  • HY-156787
    Porfimer sodium

    Photofrin II

    		 Endogenous Metabolite Cancer
    Porfimer sodium (Photofrin II) is a photosensitizing compound used primarily for photodynamic inhibition. Porfimer sodium is selectively taken up by tumor cells and can generate oxygen free radicals upon activation. Porfimer sodium causes changes in Ca(2+) concentrations within cells, exhibiting acute electrophysiological responses and changes in cell morphology. The application of porfimer sodium can lead to the formation of micropores on the cell membrane surface, resulting in necrotic cell death .
    Porfimer sodium
  • HY-N9086A
    (rac)-Poriol

    5,7,4'-Trihydroxy-6-methylflavanone

    		 NO Synthase COX Interleukin Related Inflammation/Immunology
    (rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β .
    (rac)-Poriol

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