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Results for "

galactosylceramide

" in MedChemExpress (MCE) Product Catalog:

23

Inhibitors & Agonists

3

Fluorescent Dye

12

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-102022
    α-Galactosylceramide
    2 Publications Verification

    α-GalCer; KRN7000

    		 Others Inflammation/Immunology Cancer
    α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
    α-Galactosylceramide
  • HY-151240
    Galactosylceramide

    		Endogenous Metabolite Neurological Disease
    Galactosylceramide (GalC) is a glucosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation.
    Galactosylceramide
  • HY-D1575
    C6 NBD Galactosylceramide

    		Fluorescent Dye Others
    C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) .
    C6 NBD Galactosylceramide
  • HY-145493
    C12 NBD Galactosylceramide

    		Fluorescent Dye Others
    C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .
    C12 NBD Galactosylceramide
  • HY-165855
    Octanoyl-galactosylceramide

    		Others Metabolic Disease
    Octanoyl-galactosylceramide is an ester product.
    Octanoyl-galactosylceramide
  • HY-165892
    Dodecanoyl-galactosylceramide

    		Others Metabolic Disease
    Dodecanoyl-galactosylceramide is an ester product.
    Dodecanoyl-galactosylceramide
  • HY-166118
    N-Hexanoyl-biotin-galactosylceramide

    		Others Metabolic Disease
    N-Hexanoyl-biotin-galactosylceramide is an ester product.
    N-Hexanoyl-biotin-galactosylceramide
  • HY-166293
    7DW8-5

    4-Fluorophenylundecanoyl-α-galactosylceramide

    		 Others Metabolic Disease
    7DW8-5 (4-Fluorophenylundecanoyl-α-galactosylceramide) is an ester product.
    7DW8-5
  • HY-165072
    C2 3'-Sulfo galactosylceramide (d18:1/2:0)

    C2 Sulfatide; N-Acetyl sulfatide

    		 Others Others
    C2 3'-Sulfo galactosylceramide (d18:1/2:0) (C2 Sulfatide) is one of the sulfatide class of glycolipids. C2 3'-Sulfo galactosylceramide (d18:1/2:0) can be used in the quantification of lysosulfatides in mouse brain tissue and plasma .
    C2 3'-Sulfo galactosylceramide (d18:1/2:0)
  • HY-131992
    N-Acetylpsychosine

    C2 galactosylceramide (d18:1/2:0)

    		 Others Inflammation/Immunology
    N-Acetylpsychosine (C2 Galactosylceramide (d18:1/2:0)), α-galactosylated C2-ceramide, has immunostimulatory activity. N-Acetylpsychosine can be a useful tool to investigate the mechanism of apoptosis and the immune reponses induced by dendritic cells (DCs) .
    N-Acetylpsychosine
  • HY-125726
    Sulfo galactosylceramide

    (3'-sulfo)Galβ-Cer(d18:1/24:1); N-Nervonoyl Sulfatide; C24:1 Sulfatide

    		 Others Inflammation/Immunology
    Sulfo galactosylceramide (N-Nervonoyl Sulfatide; C24:1 Sulfatide) is a member of the sulfatide class of glycolipids. It is the predominate sulfatide species in mature myelin, and it accumulates at a higher rate than C24 3’-sulfo galactosylceramide in rat cerebellum from seven to 32 days of age when active myelination occurs. It interacts with C-type lectins and immunoglobulin-like receptors with the highest affinity for LMIR5. It induces production of MCP-1 in basophils but not mast cells and increases the activation of NFAT in a reporter assay via LMIR5. Sulfo galactosylceramide is an immunodominant species in myelin, is bound by CD1d in vitro, and increases proliferation in isolated mouse splenocytes. It reduces symptoms and increases survival in a mouse model of chronic relapsing-remitting experimental autoimmune encephalomyelitis (EAE) when used at a dose of 20 μg. It also decreases the number of inflammatory lesions and infiltrating mononuclear cells in the lumbar spinal cord of EAE mice. As this product is derived from a natural source, there may be variations in the sphingoid backbone.
    Sulfo galactosylceramide
  • HY-D1579
    C12 NBD Globotriaosylceramide

    		Fluorescent Dye Others
    C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .
    C12 NBD Globotriaosylceramide
  • HY-145535
    Tetracosanoyl-sulfatide

    C24 3'-sulfo galactosylceramide (d18:1/24:0)

    		 Endogenous Metabolite Metabolic Disease
    Tetracosanoyl-sulfatide is an endogenous metabolite present in Urine that can be used for the research of Mild Metachromatic Leukodystrophy .
    Tetracosanoyl-sulfatide
  • HY-137798
    Chromozym PL

    		Fluorescent Dye Others
    Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
    Chromozym PL
  • HY-P4154
    Bevonescein

    ALM-488

    		 Fluorescent Dye Neurological Disease
    Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
    Bevonescein
  • HY-144120
    αGalCer-RBD

    		SARS-CoV Infection
    αGalCer-RBD is a self-adjuvanting lipoprotein conjugate. αGalCer-RBD induces potent immunity against SARS-CoV-2 and its variants of concern. αGalCer-RBD conjugate induces RBD-specific, cytokine-producing T cell development. αGalCer-RBD has great potential to be an effective COVID-19 vaccine candidate. α-Galactosylceramide (αGalCer) is a potent invariant natural killer T cell (iNKT) agonist . RBD: receptor-binding domain
    αGalCer-RBD
  • HY-142975
    N-Pentadecanoyl-psychosine

    C15 galactosylceramide (d18:1/15:0); GalCer(d18:1/15:0)

    		 Others Others
    N-Pentadecanoyl-psychosine is a glycolipid that can be used in membrane adhesion studies .
    N-Pentadecanoyl-psychosine
  • HY-P1103A
    CTCE-9908 TFA

    		CXCR Cancer
    CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
    CTCE-9908 TFA
  • HY-P1103
    CTCE-9908
    1 Publications Verification

    		 CXCR Cancer
    CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
    CTCE-9908
  • HY-P2231A
    Cotadutide acetate
    1 Publications Verification

    MEDI0382 acetate

    		 GCGR Metabolic Disease
    Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
    Cotadutide acetate
  • HY-P2231
    Cotadutide
    1 Publications Verification

    MEDI0382

    		 GCGR Metabolic Disease
    Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
    Cotadutide
  • HY-P1321
    GR231118

    1229U91; GW1229

    		 Neuropeptide Y Receptor Neurological Disease
    GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
    GR231118
  • HY-P1321A
    GR231118 TFA

    1229U91 TFA; GW1229 TFA

    		 Neuropeptide Y Receptor Neurological Disease
    GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
    GR231118 TFA

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