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Results for "

glycoprotein-IIb

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Integrin (11)
By Research Areas:	Cancer (1) Cardiovascular Disease (13) Inflammation/Immunology (1) Metabolic Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Antibodies

Targets Recommended: Glycoprotein VI P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10309

Sibrafiban RO 48-3657	Integrin	Cardiovascular Disease
Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .

HY-B0686

Eptifibatide Maximum Cited Publications 6 Publications Verification	Integrin	Cardiovascular Disease
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P0074

GPRP 1 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Integrin	Cardiovascular Disease
GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-101720A

Fradafiban hydrochloride BIBU-52 hydrochloride	Integrin	Cardiovascular Disease
Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a K_d value of 148 nM.

HY-P0074A

GPRP acetate 1 Publications Verification Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate	Integrin	Cardiovascular Disease
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-101720

Fradafiban BIBU-52	Integrin	Cardiovascular Disease
Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a K_d value of 148 nM.

HY-B0686A

Eptifibatide monoacetate	Integrin	Cardiovascular Disease
Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-125668

Ro 43-5054	Integrin	Cancer
Ro 43-5054 is a platelet glycoprotein IIb-IIIa receptor antagonist. Ro 43-5054 can be used in the research of early reocclusion after thrombolytic therapy .

HY-10308

Lefradafiban	Others	Metabolic Disease
Lefradafiban is an orally active glycoprotein IIb/IIIa receptor antagonist. Lefradafiban can be metabolized to its active form, Fradafiban, a non-peptide GP IIb/IIIa receptor antagonist .

HY-111348

Lamifiban Ro 44-9883	Others	Cardiovascular Disease
Lamifiban is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban is promising for research of acute coronary syndromes .

HY-111348A

Lamifiban TFA	Others	Cardiovascular Disease
Lamifiban TFA is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban TFA in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban TFA is promising for research of acute coronary syndromes .

HY-P9934

Abciximab C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

HY-U00235

SR121566A	Integrin	Inflammation/Immunology
SR121566A is a novel non-peptide *Glycoprotein IIb/IIIa* (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC₅₀s of 46±7.5, 56±6 and 42±3 nM, respectively.

HY-126039

L-739758	Integrin	Cardiovascular Disease
L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa). L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research .

HY-146332

Collagen-IN-1	Others	Cardiovascular Disease
Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC₅₀ value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .

Cat. No.	Product Name	Target	Research Area

HY-B0686

Eptifibatide Maximum Cited Publications 6 Publications Verification	Integrin	Cardiovascular Disease
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P0074

GPRP 1 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Integrin	Cardiovascular Disease
GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-P0074A

GPRP acetate 1 Publications Verification Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate	Integrin	Cardiovascular Disease
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-B0686A

Eptifibatide monoacetate	Integrin	Cardiovascular Disease
Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P3082

SKF 106760	Peptides	Cardiovascular Disease
SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis .

Cat. No.	Product Name	Target	Research Area

HY-P9934

Abciximab C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82094

	Integrin alpha IIb Antibody (YA1839) ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41	WB	Human, Rat
	Integrin alpha IIb Antibody (YA1839) is a biotin-conjugated non-conjugated IgG antibody, targeting Integrin alpha IIb, with a predicted molecular weight of 113 kDa (observed band size: 137 kDa). Integrin alpha IIb Antibody (YA1839) can be used for WB experiment in human, rat background.

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