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Isoforms Recommended:	CA Ⅱ

Results for "

hCAII

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Carbonic Anhydrase (28) Cholinesterase (ChE) (2) β-glucuronidase (2)
By Research Areas:	Cancer (22) Endocrinology (1) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (6)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-152140

hCAII-IN-8	Carbonic Anhydrase	Cancer
hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC₅₀ value of 0.18 μM against hCA II .

HY-168855

hCAII/IX-IN-1	Carbonic Anhydrase	Cancer
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of *hCAII* and hCAIX, with the K_is of 7.4 and 7.0 nM, respectively. hCAII/IX-IN-1 plays an important role in cancer research .

HY-144264

hCAII-IN-6	Carbonic Anhydrase	Endocrinology
hCAII-IN-6 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor with a K_i of 4.4 nM. hCAII-IN-6 also inhibits other hCAs isoforms I, IV and IX, with K_i values of 9.2 nM, 480.2 nM and 14.7 nM, respectively. hCAII-IN-6 can be used for glaucoma research .

HY-150973

hCAII-IN-4	Carbonic Anhydrase β-glucuronidase	Neurological Disease Metabolic Disease Cancer
hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC₅₀ of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronidase with an IC₅₀ of 773.9 μM .

HY-161282

hCAII-IN-10	Carbonic Anhydrase	Neurological Disease Cancer
hCAII-IN-10 (compound 11d) is hCA II inhibitor with the IC₅₀s of 14 nM and 29.2 μM for hCA II and hCA I, respectively. hCAII-IN-10 inhibits cell growth against HT-29 cells with the IC₅₀ of 74 μM. hCAII-IN-10 shows strongly lowered intraocular pressure in the glaucomatous rabbit eye model .

HY-146982

hCAII-IN-1	Carbonic Anhydrase	Cancer
hCAII-IN-1 (compound 7f) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with K_is of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has the potential for the research of cancer diseases .

HY-168856

hCAII/XII-IN-1	Carbonic Anhydrase	Cancer
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and *hCAII, with K_i*s of 8.4 and 9.4 nM, respectively. hCAXII-IN-11 plays an important role in cancer research .

HY-152141

hCAII-IN-9	Carbonic Anhydrase	Others
hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC₅₀s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability .

HY-150975

hCAII-IN-5	Carbonic Anhydrase	Cancer
hCAII-IN-5 (compound 12h) is a potent and selective hCA II inhibitor with an IC₅₀ value of 4.55 μM .

HY-144268

hCAII-IN-7	Carbonic Anhydrase	Cancer
hCAII-IN-7 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor with K_is of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively .

HY-146355

hCAII-IN-2	Carbonic Anhydrase	Cancer
hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with K_i values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively .

HY-146008

hCAII-IN-3	Carbonic Anhydrase	Cancer
hCAII-IN-3 (Compound 16) is a human carbonic anhydrase (hCA) inhibitor with K_i values of 403.8, 5.1, 10.2 and 5.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-2 shows anticancer activity .

HY-150977

*β-Glucuronidase/hCAII-IN-2*	Carbonic Anhydrase	Neurological Disease Metabolic Disease Cancer
β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC₅₀ of 670.7 μM and 21.77 μM, respectively .

HY-150976

*β-Glucuronidase/hCAII-IN-1*	Carbonic Anhydrase β-glucuronidase	Neurological Disease Metabolic Disease Cancer
β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC₅₀ of 440.1 μM and 4.91 μM, respectively .

HY-149301

hCAIX-IN-18	Carbonic Anhydrase	Cancer
hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with K_is of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for *hCAI, hCAII, hCAIX, hCAXII*, respectively. hCAIX-IN-18 can be used for cancer research .

HY-146983

hCAIX-IN-3	Carbonic Anhydrase	Cancer
hCAII-IN-3 (compound 7e) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with K_is of 124.2 and 30.5 nM, respectively. hCAII-IN-3 has the potential for the research of cancer diseases .

HY-147353

Phenylsulfamide	Carbonic Anhydrase	Others
Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a K_d of 45.50 μM and a K_i of 79.60 μM .

HY-172178

hCAIX/XII-IN-14	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-14 (Compound 1i) is an hCAIX/XII inhibitor, with K_i values of *hCAII, hCAIX, and hCAXII* for 9.4 nM, 5.6 nM, and 6.3 nM, respectively .

HY-147665

hCAIX-IN-7	Carbonic Anhydrase	Cancer
hCAIX-IN-7 (compound 6c) is a potent and selective hCAIX inhibitor with K_Is of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively .

HY-147662

hCAIX-IN-5	Carbonic Anhydrase	Cancer
hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with K_Is of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively .

HY-146256

hCAXII-IN-5	Carbonic Anhydrase	Cancer
hCAXII-IN-5 (compound 6o) is a potent and selective hCAXII inhibitor with K_i values of >10000, >10000, 286.1, 1.0 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .

HY-146257

hCAIX/XII-IN-2	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-2 (compound 6a) is a potent and selective hCAIX and hCAXIIinhibitor with K_i values of >10000, >10000, 30.0, 3.6 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .

HY-146258

hCAIX/XII-IN-3	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-3 (compound 6q) is a potent and selective hCAIX and hCAXIIinhibitor with K_i values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .

HY-157321

hCAI/II-IN-7	Carbonic Anhydrase	Neurological Disease
hCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with K_i values of 23 nM, 44 nM and 20.57 µM for hCA-I, hCA-II and bovine CA, respectively .

HY-161143

Carbonic anhydrase/AChE-IN-2	Cholinesterase (ChE) Carbonic Anhydrase	Neurological Disease
Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitor, with E_i of 5.07 nM, 24.42 nM and 19.95 nM for AChE, hCAI and hCAII, respectively .

HY-161322

hCAXII-IN-9	Carbonic Anhydrase	Cancer
hCAXII-IN-9 (Compound 3I) is a selective inhibitor of hCAXII with K_i values of 28 nM, 7192.6 nM, 188.6 nM, and >100000 nM for hCAXII, *hCAI, hCAII, and hCAIX*, respectively. hCAXII-IN-9 can be utilized in antitumor research .

HY-169961

BChE-IN-38	Cholinesterase (ChE)	Cancer
BChE-IN-38 (compound 13) is a potent BChE inhibitor with K_i values of 62.05, 28.78, 14.09, 1.15 nM for hCAI, hCAII, AChE, BChE, respectively. BChE-IN-38 shows cytotoxic activity .

HY-B1471

Fluorometholone acetate 1 Publications Verification	Carbonic Anhydrase	Inflammation/Immunology
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonic anhydrase (CA) with IC₅₀s of 2.18 μM and 17.5 μM for *hCA-I* and *hCA-II*, respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research .

HY-B1471R

Fluorometholone acetate (Standard)	Carbonic Anhydrase	Inflammation/Immunology
Fluorometholone acetate (Standard) is the analytical standard of Fluorometholone acetate. This product is intended for research and analytical applications. Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonic anhydrase (CA) with IC₅₀s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research .

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hCAII

Inhibitors & Agonists