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herpes simplex virus type-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HSV (16) Influenza Virus (1) Apoptosis (1) DNA/RNA Synthesis (1) EBV (1) RSV (1) SARS-CoV (1)
By Research Areas:	Cancer (1) Infection (16) Inflammation/Immunology (1) Neurological Disease (2)

16

Inhibitors & Agonists

1

Peptides

4

Natural
Products

Targets Recommended: HSV Scavenger Receptor Class B type I (SR-BI） Influenza Virus Dengue virus Virus Protease PCSK9

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

5-Nitrobarbituric acid	HSV	Infection Inflammation/Immunology
5-Nitrobarbituric acid is a **herpes simplex virus type-1 (HSV-1) inhibitor (IC₅₀**=1.7 μM) .

Tromantadine hydrochloride 1 Publications Verification	HSV	Infection
Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .

Pritelivir 3 Publications Verification AIC316; BAY 57-1293	HSV	Infection
Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC₅₀ of 0.02 μM against HSV1-2 .

Pritelivir mesylate hydrate 3 Publications Verification AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate	HSV	Infection
Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC₅₀ of 0.02 μM against HSV1-2 .

Pritelivir mesylate 3 Publications Verification AIC316 mesylate; BAY 57-1293 mesylate	HSV	Infection
Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC₅₀ of 0.02 μM against HSV1-2 .

Yatein	HSV Apoptosis	Infection Cancer
Yatein is a lignan isolated from A. chilensis, with antiproliferative activity . Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression .

Isoborneol (±)-Isoborneol	HSV	Infection Neurological Disease
Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) .

BRL44385	EBV HSV	Infection
BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and HSV2), varicella zoster virus (VZV) and Epstein-Barr virus (EBV).

Tromantadine	HSV	Infection
Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .

WAY-150138	HSV	Infection
WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled

Leachianone G	HSV	Infection
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes* simplex type 1 virus (HSV-1) with an IC₅₀ value of 1.6 μg/mL .*

BVDU 5′-Triphosphate (E)-5-(2-Bromovinyl)-dUTP; BVdUTP	DNA/RNA Synthesis HSV	Infection
BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and **herpes simplex virus type 1 (HSV-1*), due to a specific phosphorylation by the virus*-encoded thymidine kinase.

HSV-1 Protease substrate	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

HY-W747737A

BVDU 5′-Triphosphate ammonium (E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium	HSV	Infection
BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and **herpes simplex virus type 1 (HSV-1*), due to a specific phosphorylation by the virus*-encoded thymidine kinase.

Isoborneol (Standard)	HSV	Infection Neurological Disease
Isoborneol (Standard) is the analytical standard of Isoborneol. This product is intended for research and analytical applications. Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) .

Antiviral agent 58	SARS-CoV Influenza Virus RSV HSV	Infection
Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2 .

Cat. No.	Product Name	Target	Research Area

HSV-1 Protease substrate	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

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