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Results for "

host invasion

" in MedChemExpress (MCE) Product Catalog:

By Targets:	SARS-CoV (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Infection (4) Inflammation/Immunology (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124078

NIC	Others	Infection
NIC is a host invasion inhibitor. NIC can suppress host invasion by interacting with the major invasion-related protein, merozoite surface protein 1 (MSP-1). NIC prevents the invasion of Plasmodium falciparum and Plasmodium vivax into the host .

HY-W706466

3',5,5'-Trichlorosalicylanilide TCSA	Others	Infection
3',5,5'-Trichlorosalicylanilide (TCSA) acts as an inhibitor of fungal morphogenesis, preventing biofilm formation and hindering host cell invasion.

HY-14644B

Apilimod hydrochloride STA 5326 hydrochloride; LAM-002A (free base) hydrochloride; AIT-101 hydrochloride	Others	Infection Inflammation/Immunology
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.

HY-P9804

Anti-MERS-2E6 mAb MERS-2E6; MERS Antibody-2E6	SARS-CoV	Infection
Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.

HY-D1056C2

Lipopolysaccharides, from S. enterica serotype minnesota LPS, from Salmonella enterica (Serotype minnesota)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Cat. No.	Product Name	Type

HY-D1056C2

Lipopolysaccharides, from S. enterica serotype minnesota LPS, from Salmonella enterica (Serotype minnesota)	Carbohydrates
Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Lipopolysaccharides, from S. enterica serotype minnesota

LPS, from Salmonella enterica (Serotype minnesota)

Carbohydrates

Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Cat. No.	Product Name	Target	Research Area

HY-P9804

Anti-MERS-2E6 mAb MERS-2E6; MERS Antibody-2E6	SARS-CoV	Infection
Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.

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