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Results for "

human skin fibroblasts

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

4

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108999A
    Crisnatol
    1 Publications Verification

    BWA770U

    		 DNA/RNA Synthesis Cancer
    Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts .
    Crisnatol
  • HY-W020044
    DL-alpha-Tocopherol
    5 Publications Verification

    DL-α-Tocopherol

    		 Ferroptosis DNA/RNA Synthesis Apoptosis Cancer
    DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol
  • HY-119358
    Traumatic Acid
    2 Publications Verification

    		 Reactive Oxygen Species Apoptosis Cardiovascular Disease Inflammation/Immunology
    Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis .
    Traumatic Acid
  • HY-W020044R
    DL-alpha-Tocopherol (Standard)
    5 Publications Verification

    		 Ferroptosis DNA/RNA Synthesis Apoptosis Cancer
    DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol (Standard)
  • HY-15768
    Ilomastat
    Maximum Cited Publications
    45 Publications Verification

    GM6001; Galardin

    		 MMP Cancer
    Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
    Ilomastat
  • HY-108999
    Crisnatol mesylate

    BWA770U mesylate

    		 DNA/RNA Synthesis Cancer
    Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts .
    Crisnatol mesylate
  • HY-118518
    Ronipamil

    		Calcium Channel Cardiovascular Disease Cancer
    Ronipamil is a calcium ion antagonist. Ronipamil increases the specific binding and internalization of human 125I-LDL in human skin fibroblasts (HSF) and the human hepatoma cell line Hep G2 .
    Ronipamil
  • HY-W020044S
    DL-alpha-Tocopherol-13C3

    		Ferroptosis Others
    DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
    DL-alpha-Tocopherol-13C3
  • HY-W020044S1
    DL-alpha-Tocopherol-d9

    		Ferroptosis Others
    DL-alpha-Tocopherol-d9 is the deuterium labeled DL-alpha-Tocopherol[1]. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[2].
    DL-alpha-Tocopherol-d9
  • HY-N1190
    DL-Syringaresinol

    (±)-Syringaresinol

    		 p38 MAPK AP-1 Bacterial Infection
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv .
    DL-Syringaresinol
  • HY-A0087
    Octocrylene
    2 Publications Verification

    		 Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450 Others
    Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
    Octocrylene

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