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Results for "

integrin β1 (ITGB1)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1)
By Research Areas:	Cancer (1)

1

Inhibitors & Agonists

18

Recombinant Proteins

Targets Recommended: Integrin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

N-Acetylglucosaminyltransferase IVa MGAT4A	Endogenous Metabolite	Cancer
N-Acetylglucosaminyltransferase IVa (MGAT4A) is a glycosyltransferase that can enhance the migration, invasion, and adhesion abilities of cancer cells, and increase β1,4GlcNAc branched glycans on integrin β1 (ITGB1), a tumor-associated glycoprotein closely related to cell motility ^[1].

Species:	Human (14) Mouse (3) Cynomolgus (1)
Tag:	His (18) Avi (6) Flag (2)
Source:	HEK293 (18)

Cat. No.	Compare	Product Name	Species	Source

	Integrin alpha 2 beta 1 Protein, Mouse (HEK293, His) α2β1; ITGA2&ITGB1; ITGA2; ITGB1	Mouse	HEK293
	Integrin α-2/β-1 is a key collagen receptor that focuses platelet and cell adhesion to collagen and regulates collagen and collagenase gene expression.In addition to its collagen-related functions, it contributes to force generation, extracellular matrix organization, and recognition of laminin, collagen C propeptide, and E-cadherin.Integrin alpha 2 beta 1 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha 2 beta 1 protein, expressed by HEK293 , with C-His labeled tag.Integrin alpha 2 beta 1 Protein.

	Integrin alpha 8 beta 1 Protein, Human (HEK293, His) integrin alpha 8 beta 1; ITGA8; ITGB1	Human	HEK293
	Integrin alpha-8/beta-1 orchestrates mesenchymal cell recruitment during kidney organogenesis, recognizing the R-G-D sequence in ligands like TNC, FN1, SPP1, TGFB1, TGFB3, and VTN. Its role in diverse cellular interactions, crucial for organ formation, includes NPNT as a functional ligand in kidney genesis. As a neuronal receptor for TNC, it modulates neurite outgrowth in sensory and motor neurons. Structurally, Integrin alpha-8/beta-1 forms a heterodimer with the alpha-8 subunit associating with the beta-1 subunit, emphasizing its integral role in cell-matrix and cell-cell interactions during organ development and neural processes. Integrin alpha 8 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 8 beta 1 Protein, Human (HEK293, His), has molecular weight of 120-140 kDa & 100-120 kDa, respectively.

	Integrin alpha 2 beta 1 Protein, Human (HEK293, His) α2β1; integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2, GPIa-IIa, CD49b; integrin alpha A1 β 1; alpha A1 β 1; β 1	Human	HEK293
	ITGA2 Protein, a transmembrane receptor, is involved in cell adhesion, platelet aggregation, and tumor metastasis. Dysregulation of ITGA2 Protein has been associated with various disorders, including thrombosis and cancer. Targeting ITGA2 Protein may offer potential therapeutic interventions in these conditions by modulating cell adhesion, inhibiting blood clot formation, and preventing tumor metastasis. Integrin alpha 2 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 2 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 2 beta 1 Protein, Human (HEK293, His), has molecular weight of 110-140 kDa.

	Integrin alpha 8 beta 1 Protein, Human (HEK293, Flag, His) integrin alpha 8 beta 1; ITGA8; ITGB1	Human	HEK293
	Integrin alpha-8/beta-1 orchestrates mesenchymal cell recruitment during kidney organogenesis, recognizing the R-G-D sequence in ligands like TNC, FN1, SPP1, TGFB1, TGFB3, and VTN. Its role in diverse cellular interactions, crucial for organ formation, includes NPNT as a functional ligand in kidney genesis. As a neuronal receptor for TNC, it modulates neurite outgrowth in sensory and motor neurons. Structurally, Integrin alpha-8/beta-1 forms a heterodimer with the alpha-8 subunit associating with the beta-1 subunit, emphasizing its integral role in cell-matrix and cell-cell interactions during organ development and neural processes. Integrin alpha 8 beta 1 Protein, Human (HEK293, Flag, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein, expressed by HEK293, with C-10*His, C-Flag labeled tag. Integrin alpha 8 beta 1 Protein, Human (HEK293, Flag, His), has molecular weight of ~85-140 kDa.

	Integrin beta-1/CD29 Protein, Human (HEK293, His) rHuintegrin beta-1/ITGB1, His; integrin Beta-1; Fibronectin Receptor Subunit Beta; VLA-4 Subunit Beta; CD29; ITGB1; FNRB; MDF2; MSK12	Human	HEK293
	Integrin beta-1/CD29 forms distinct heterodimers that act as multifunctional receptors for extracellular matrix proteins. It recognizes collagen, fibronectin, fibrinogen and laminin and plays a key role in cell functions such as migration, adhesion and angiogenesis. Integrin beta-1/CD29 Protein, Human (708a.a, HEK293, His) is the recombinant human-derived Integrin beta-1/CD29 protein, expressed by HEK293 , with C-6*His labeled tag.

	Integrin alpha 5 beta 1 Protein, Human (HEK293, Flag-His) CD49e; FNRA; integrin alpha 5 beta 1; integrin alpha-F; VLA-5; ITGB1; CD29	Human	HEK293
	ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin, fibrinogen, PLA2G2A, fibrillin-1 (FBN1), IL1B, human metapneumovirus, and soluble CD40LG. ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites. Integrin alpha 5 beta 1 Protein, Human (HEK293, Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein, expressed by HEK293 , with C-Flag, C-10*His labeled tag. Integrin alpha 5 beta 1 Protein, Human (HEK293, Flag-His), has molecular weight of ~101.35 kDa.

	Integrin alpha A1 beta 1 Protein, Human (HEK293, His) integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; integrin alpha A1 β 1; alpha A1 β 1; β 1	Human	HEK293
	ITGA1 Protein, a cell surface receptor, plays a crucial role in cell adhesion, migration, and tissue development. Dysregulation of ITGA1 Protein has been linked to various diseases, including cancer and fibrosis. Targeting ITGA1 Protein may provide potential therapeutic interventions in these conditions by modulating cell adhesion, inhibiting tumor growth, and preventing tissue fibrosis. Integrin alpha A1 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha A1 beta 1 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha A1 beta 1 Protein, Human (HEK293, His), has molecular weight of 160-200 kDa.

	Integrin alpha A1 beta 1 Protein, Mouse (HEK293, His) integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; integrin alpha A1 β 1; alpha A1 β 1; β 1	Mouse	HEK293
	Integrin alpha-1/beta-1, a receptor for laminin and collagen, recognizes the proline-hydroxylated sequence G-F-P-G-E-R within collagen. This integral protein negatively regulates EGF-stimulated cell growth and forms a heterodimeric complex with beta-1, interacting with the small GTPase RAB21. Through its cytoplasmic domain, Integrin alpha-1/beta-1 engages with PTPN2, activating phosphatase activity towards EGFR, exerting a negative regulatory influence on EGF signaling, highlighting its multifaceted role in cellular responses. Integrin alpha A1 beta 1 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha A1 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha A1 beta 1 Protein, Mouse (HEK293, His), has molecular weight of 140-200 kDa (ITGA1) & 100-115 kDa (ITGB1), respectively.

	Integrin alpha 6 beta 1 Protein, Human (HEK293, His-Avi) α6β1; integrin alpha 6 beta 1; ITGA6&ITGB1; integrin alpha 6 β 1	Human	HEK293
	Integrin alpha 6 beta 1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Integrin alpha 6 beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. , has molecular weight of 110-130 kDa.

	Integrin alpha 6 beta 1 Protein, Human (Biotinylated, HEK293, His, Avi) α6β1; integrin alpha 6 beta 1; ITGA6&ITGB1; integrin alpha 6 β 1	Human	HEK293
	Integrin alpha 6 beta 1 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived Integrin alpha 6 beta 1, expressed by HEK293 , with C-Avi, C-His labeled tag. ,

	Integrin alpha 5 beta 1 Protein, Human (Biotinylated, HEK293, His-Avi) integrin alpha 5 beta 1; VLA-5; ITGA5&ITGB1; integrin alpha 5 β 1; α5β1	Human	HEK293
	ITGA5, a versatile receptor, interacts with diverse ligands such as fibronectin, fibrinogen, PLA2G2A, fibrillin-1 (FBN1), IL1B, Human metapneumovirus, and soluble CD40LG. Recognizing the R-G-D sequence, ITGA5 mediates cell adhesion through distinct binding sites. Notably, it binds PLA2G2A at a separate site, inducing conformational changes enhancing ligand binding. ITGA5's role in IL1B signaling, microbial infection, and CD40/CD40LG signaling highlights its multifunctionality in cellular processes and signaling pathways. Integrin alpha 5 beta 1 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein, expressed by HEK293, with C-Avi, C-His labeled tag. Integrin alpha 5 beta 1 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 110-140 kDa.

	Integrin alpha V beta 1 Protein, Human (HEK293, His, Avi) ITGAV:ITGB1	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 1 Protein, Human (HEK293, His, Avi) is the recombinant human-derived Integrin alpha V beta 1, expressed by HEK293 , with C-Avi, C-His labeled tag. ,

	Integrin alpha 10 beta 1 Protein, Human (HEK293, His) integrin alpha 10 beta 1; ITGA10&ITGB1; α10β1	Human	HEK293
	Integrin alpha-10/beta-1, a collagen-specific receptor, crucially mediates cell interactions with the extracellular matrix. Comprising alpha-10 and beta-1 subunits, their stable association forms a heterodimeric complex. This interaction facilitates adhesion and signaling events, influencing essential aspects of cell behavior and tissue organization. Understanding Integrin alpha-10/beta-1's nuances provides insights into its significance in mediating cell-matrix interactions, offering implications in physiological and pathological contexts. Integrin alpha 10 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 10 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 10 beta 1 Protein, Human (HEK293, His), has molecular weight of 140-160 kDa (ITGA10) & 100-130 kDa (ITGB), respectively.

	Integrin alpha 10 beta 1 Protein, Mouse (HEK293, His) integrin alpha 10 beta 1; ITGA10&ITGB1; α10β1	Mouse	HEK293
	Integrin alpha 10 beta 1 Protein, within the integrin alpha chain family, is emphasized. Integrin alpha 10 beta 1 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha 10 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 10 beta 1 Protein, Mouse (HEK293, His), has molecular weight of 140-170 kDa (ITGA10) & 100-130 kDa (ITGB), respectively.

	Integrin alpha 5 beta 1 Protein, Human (HEK293, His-Avi) integrin alpha 5 beta 1; VLA-5; ITGA5&ITGB1	Human	HEK293
	ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin, fibrinogen, PLA2G2A, fibrillin-1 (FBN1), IL1B, human metapneumovirus, and soluble CD40LG. ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites. Integrin alpha 5 beta 1 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha 5 beta 1 Protein, Human (HEK293, His-Avi), has molecular weight of 100-140 kDa.

	Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein, Cynomolgus (HEK293, His)	Cynomolgus	HEK293

	Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, Human (HEK293, His)	Human	HEK293

	Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, Human (HEK293, His, Avi)	Human	HEK293

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