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Results for "

jack bean urease

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2767
    Urease, Jack bean

    		Bacterial Others
    Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.
    Urease, Jack bean
  • HY-115939
    Urease-IN-2

    		Bacterial Infection
    Urease-IN-2 (compound 8g) is a non-competitive urease inhibitor with an IC50 of 0.94 μM and a Ki of 1.6 μM. Urease-IN-2 inhibits the Jack bean urease (JBU) in a non-competitive manner .
    Urease-IN-2
  • HY-149775
    Urease-IN-10

    		Bacterial Infection
    Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner .
    Urease-IN-10
  • HY-W176199
    DPPD-Q

    		Reactive Oxygen Species Metabolic Disease
    DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD, which is found in tire wear particles and crumb rubber, particulate matter 2.5 (PM2.5), and wastewater influent and effluent. DPPD-Q inhibits jack bean urease by 91.4% at 5 µM .
    DPPD-Q
  • HY-N9746
    (R)-4-Methoxydalbergione

    		Parasite Infection
    (R)-4-Methoxydalbergione is a urease inhibitor with IC50s of 59.72 and 67.33 μM for Bacillus pasteurii urease and Jack bean urease. (R)-4-Methoxydalbergione also has antiplasmodial activity. (R)-4-Methoxydalbergione can be isolated from Ranunculus repens .
    (R)-4-Methoxydalbergione
  • HY-161860
    Antibacterial agent 233

    		Bacterial Cancer
    Antibacterial agent 233 (Compound 7c) exhibits inhibitory efficacy against Helicobacter pylori with MIC of 0.4-1.6 μg/mL. Antibacterial agent 233 inhibits jack bean urease (IC50 is 0.27 μg/mL), changes the permeability of H. pylori cell membrane, causes the leakage of cellular contents. Antibacterial agent 233 exhibits metabolic stability in whole blood and artificial gastric fluid. Antibacterial agent 233 exhibits antitumor efficacy against U2OS in mice .
    Antibacterial agent 233

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