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lipid vesicles

" in MedChemExpress (MCE) Product Catalog:

26

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2

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3

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5

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7

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1435

    Na+/K+ ATPase Neurological Disease
    Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na + + K +)-ATPase in reconstituted vesicles .
    Oxonol VI
  • HY-156237

    Autophagy Others
    Beclin1-ATG14L interaction inhibitor 1 (com 19) is a selective Beclin1-ATG14L interaction inhibitor. This protein interaction mechanism specifically targets complex I of the lipid kinase VPS34 without affecting complex II. Because the integrity of VPS34 complex II depends on the Beclin 1-UVRAG interaction. Beclin1-ATG14L interaction inhibitor 1 can disrupt the formation of VPS34 complex I and inhibit autophagy, but does not affect complex II-related vesicle transport .
    Beclin1-ATG14L interaction inhibitor 1
  • HY-148978

    Endogenous Metabolite Metabolic Disease
    18:0,18:1 PS sodium is a lipid component of synaptic vesicles and cholesterol, which can be used for metabolic research .
    18:0,18:1 PS sodium
  • HY-D0040
    Calcein
    5+ Cited Publications

    Fluorexon

    Fluorescent Dye Others
    Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium.
    Calcein
  • HY-148977

    Endogenous Metabolite Metabolic Disease
    18:0,22:6 PS sodium is a lipid component of synaptic vesicles and cholesterol, which can be used for metabolic research .
    18:0,22:6 PS sodium
  • HY-143695

    Liposome Others
    16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver agents .
    16:0 TAP
  • HY-162543

    18:1 Lissamine rhodamine PE

    Liposome Others
    18:1 Liss Rhod PE (18:1 Lissamine rhodamine PE) is a fluorescently labeled lipid. It can be used to label giant monolayer vesicles and DOPC .
    18:1 Liss Rhod PE
  • HY-145502

    Biochemical Assay Reagents Others
    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .
    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium)
  • HY-134939

    Others Others
    thio-Miltefosine is a modulator of rafts in membrane tissue. Rafts are nanoscale aggregates of different lipids and proteins that profoundly affect cellular function. Thio-Miltefosine modulates membrane phase behavior on cell-derived giant plasma membrane vesicles .
    thio-Miltefosine
  • HY-13554

    Antibiotic Infection Cancer
    Annamycin is an antibiotic, that has high affinity for lipid membranes and can bypass the multidrug resistance protein-1 (MDR-1 ) mechanism of cellular drug resistance. Annamycin exhibits antitumor efficacy in multilamellar vesicles against solid tumor .
    Annamycin
  • HY-W073074

    VSV Infection
    Mesoporphyrin IX (dihydrochloride) is a photosensitizer that can be used to modify liposomes. Mesoporphyrin IX (dihydrochloride) can insert into lipid vesicles and disrupt the viral membrane structure in vesicular stomatitis virus (VSV), inducing cross-linking of VSV glycoproteins, thereby inhibiting viral activity .
    Mesoporphyrin IX dihydrochloride
  • HY-D1560

    Fluorescent Dye Others
    FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .
    FG 488 DHPE
  • HY-145539

    Liposome Others
    12-Dipalmitoyl-sn-glycero-3-PS sodium salt is an anionic diacyl phospholipid, a lipid component in cell membrane. 12-Dipalmitoyl-sn-glycero-3-PS sodium salt can be use in the preparation of catanionic vesicles and liposome .
    12-Dipalmitoyl-sn-glycero-3-PS sodium salt
  • HY-W440985

    1,2-dilauroyl-sn-glycero-3-phospho-L-serine

    Liposome Cancer
    DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
    DLPS
  • HY-P5878

    Biochemical Assay Reagents Metabolic Disease
    RG33 Peptide is a diabetes inhibitor that significantly improves glucose clearance in insulin-resistant mice. RG33 Peptide effectively solubilizes lipid vesicles and promotes cholesterol efflux in cultured macrophages. RG33 Peptide is used in research into type 2 diabetes (T2D) .
    RG33 Peptide
  • HY-W440986

    DSPS sodium

    Liposome Others
    Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
    Distearoylphosphatidylserine sodium
  • HY-150220

    Liposome Others
    1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate can be used for the synthesis of phospholipid vesicle and improve the encapsulation efficiency of proteins .
    1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate
  • HY-W714524

    1,2-POPS; 1,2-POPS; 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium; 1-Hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine sodium salt

    Liposome Metabolic Disease
    2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium
  • HY-115739

    Ras Neurological Disease Cancer
    RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 μM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively .
    RTIL 13
  • HY-P0269

    Magainin I

    Bacterial Fungal Antibiotic Infection
    Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .
    Magainin 1
  • HY-P0269A

    Magainin I TFA

    Bacterial Fungal Antibiotic Infection
    Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .
    Magainin 1 TFA
  • HY-153725

    Liposome Cancer
    17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
    17:1 Lyso PC
  • HY-W591449

    Liposome Cancer
    DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
    DOPE-PEG-Azide, MW 2000
  • HY-142989

    Liposome Others
    1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .
    1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine
  • HY-131682

    3-Hexanoyl-NBD-cholesterol

    Fluorescent Dye Others
    3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .
    3-C6-NBD-cholesterol
  • HY-135115

    3,4-DHPEA-EA

    Others Inflammation/Immunology
    Oleuropein aglycone is a polyphenol and an aglycone form of Oleuropein (HY-N0292) that has been found in extra virgin olive oil and has diverse biological activities. It is formed from oleuropein via enzymatic, acidic, or acetyl hydrolysis. Dietary administration of oleuropein aglycone (50 mg/kg of food) increases the number of neuronal autophagic vesicles and reverses cognitive deficits in a TgCRND8 transgenic mouse model of Alzheimer’s disease. It also decreases cortical and hippocampal levels of histone deacetylase 2 (HDAC2) and restores long-term potentiation in the same model. Oleuropein aglycone increases urinary norepinephrine, as well as interscapular brown adipose tissue epinephrine and UCP1 protein levels, and decreases plasma leptin levels and total abdominal cavity adipose tissue weight in a rat model of high-fat diet-induced obesity. It also reduces lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy.
    Oleuropein Aglycone

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