Search Result

Results for "

metalloenzyme

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Arginase (1) Bacterial (3) Carbonic Anhydrase (4) Endogenous Metabolite (1) HDAC (1) MMP (1) Proteasome (1) SARS-CoV (1) Tyrosinase (4)
By Research Areas:	Cancer (5) Endocrinology (1) Infection (4) Inflammation/Immunology (2) Metabolic Disease (4) Neurological Disease (3)

Inhibitors & Agonists

Screening Libraries

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2910

Galactose Oxidase, Dactylium dendroides 1 Publications Verification GOase	Endogenous Metabolite	Others
Galactose Oxidase, Dactylium dendroides (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide .

HY-135890

CG347B 2 Publications Verification	HDAC	Neurological Disease Inflammation/Immunology Cancer
CG347B is a selective HDAC6 inhibitor, also involves in synthesis of other metalloenzyme inhibitors. HDAC6 inhibitors can be used for oncology, immunology, and neurology research .

HY-P1775A

Carbonic anhydrase (isoenzyme)	Carbonic Anhydrase	Neurological Disease Metabolic Disease Cancer
Carbonic anhydrase isoenzyme is the isoenzyme of Carbonic anhydrase (HY-P1775). Carbonic anhydrase isoenzyme is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase isoenzyme catalyzes reversible conversion of carbon dioxide to bicarbonate and protons, and can be used for the research of cancer, glaucoma, obesity and epilepsy .

HY-P1775

Carbonic anhydrase, Bovine erythrocytes EC 4.2.1.1	Carbonic Anhydrase	Neurological Disease Metabolic Disease Cancer
Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing *metalloenzyme* present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy .

HY-143449

Tyrosinase-IN-2	Tyrosinase	Others
Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives .

HY-B0483

Tioxolone	Carbonic Anhydrase	Metabolic Disease
Tioxolone is an inhibitor of the metalloenzyme carbonic anhydrase I and has anti-acne activity.

HY-121021

BB-78485	Bacterial	Infection
BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC₅₀ value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials .

HY-143450

Tyrosinase-IN-3	Tyrosinase	Others
Tyrosinase-IN-3 (compound 54) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-3 has the potential for the research of skin whitening agents and food preservatives .

HY-143451

Tyrosinase-IN-4	Tyrosinase	Others
Tyrosinase-IN-4 (compound 34) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-4 has the potential for the research of skin whitening agents and food preservatives .

HY-143448

Tyrosinase-IN-1	Tyrosinase	Others
Tyrosinase-IN-1 (compound 90) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-1 has the potential for the research of skin whitening agents and food preservatives .

HY-B0483R

Tioxolone (Standard)	Carbonic Anhydrase	Metabolic Disease
Tioxolone (Standard) is the analytical standard of Tioxolone. This product is intended for research and analytical applications. Tioxolone is an inhibitor of the metalloenzyme carbonic anhydrase I and has anti-acne activity.

HY-19548

BEC	Arginase	Endocrinology
BEC, an arginine analogue, is a slow-binding competitive inhibitor of the *binuclear manganese metalloenzyme* arginase**. BEC enhances substrate flux to NO synthase, thereby enhancing NO-dependent smooth muscle relaxation in the corpus cavernosum, and enhances penile erection .

HY-100518

T-26c 2 Publications Verification	MMP	Inflammation/Immunology
T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC₅₀ of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes .

HY-138869

AubipyOMe	Others	Cancer
AubipyOMe serves as a potent inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme found in activated osteoclasts and macrophages, demonstrating IC₅₀ values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, while effectively inhibiting TRAP activity in extracts from murine macrophages and human lung tissue.

HY-P4910

Baceridin	Proteasome Apoptosis	Cancer
Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research .

HY-131907

LpxC-IN-5	Bacterial	Infection
LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with an IC₅₀ of 20 nM. LpxC-IN-5 shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 μg/mL, respectively .

HY-152101

LY1	SARS-CoV	Infection
LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PL ^pro and M ^pro with K_d values of 1.5 μM and 2.3 μM for M ^pro C145A protein and PL ^pro C111A protein, respectively. LY1 potent against the viral proteases, with IC₅₀s of 0.12 μM and 0.99 μM against M ^pro and PL ^pro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme .

HY-143249

MtMetAP1-IN-1	Bacterial	Infection
MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1). MtMetAP1-IN-1 exerts antimycobacterial activity .

Cat. No.	Product Name

HY-L081

Phosphatase Inhibitor Library	128 compounds
Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc. Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action. MCE supplies a unique collection of 128 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

Phosphatase Inhibitor Library

128 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 128 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

Cat. No.	Product Name	Target	Research Area

HY-P4910

Baceridin	Proteasome Apoptosis	Cancer
Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research .

HY-P2120

Pseudobactin A	Peptides	Others
Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.