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Results for "

miR-377

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MicroRNA (9)
By Research Areas:	Cancer (8) Cardiovascular Disease (1)
Oligonucleotides:	miRNA mimics (2) miRNA agomirs (2) miRNA antagomirs (2) MicroRNAs (8) miRNA inhibitors (2)

Inhibitors & Agonists

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-138647

*TGP-377/421* Targapre-miR-377/421	MicroRNA	Cardiovascular Disease
TGP-377/421 (Targapre-miR-377/421) is a potent *miR-377* and miR-421 inhibitor that binds a functional site in both miRNAs .

HY-R00842

*hsa-miR-377-3p mimic*	MicroRNA	Cancer
hsa-miR-377-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-377-3p mimic hsa-miR-377-3p mimic

HY-R04449

*rno-miR-377-3p mimic*	MicroRNA	Cancer
rno-miR-377-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

rno-miR-377-3p mimic rno-miR-377-3p mimic

HY-RI00842

*hsa-miR-377-3p inhibitor*	MicroRNA	Cancer
hsa-miR-377-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-377-3p inhibitor hsa-miR-377-3p inhibitor

HY-RI04449

*rno-miR-377-3p inhibitor*	MicroRNA	Cancer
rno-miR-377-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

rno-miR-377-3p inhibitor rno-miR-377-3p inhibitor

HY-R00842A

*hsa-miR-377-3p agomir*	MicroRNA	Cancer
hsa-miR-377-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-377-3p agomir hsa-miR-377-3p agomir

HY-R04449A

*rno-miR-377-3p agomir*	MicroRNA	Cancer
rno-miR-377-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

rno-miR-377-3p agomir rno-miR-377-3p agomir

HY-RI00842A

*hsa-miR-377-3p antagomir*	MicroRNA	Cancer
hsa-miR-377-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-377-3p antagomir hsa-miR-377-3p antagomir

HY-RI04449A

*rno-miR-377-3p antagomir*	MicroRNA	Cancer
rno-miR-377-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

rno-miR-377-3p antagomir rno-miR-377-3p antagomir

Cat. No.	Product Name		Classification