Search Result

Results for "

morpholino

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Arp2/3 Complex (4) Bacterial (1) Biochemical Assay Reagents (2) DNA/RNA Synthesis (10) Guanylate Cyclase (1) Nucleoside Antimetabolite/Analog (8) PI3K (1)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (1) Metabolic Disease (2)
Oligonucleotides:	Nucleosides and their Analogs (3) Nucleoside Phosphoramidites (10) Antisense Oligonucleotides (7)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W047388

*1-Deoxy-1-morpholino-D-fructose*	Biochemical Assay Reagents	Others
1-Deoxy-1-morpholino-D-fructose can be used in sugar science research.

HY-154665

*N4-Benzoyl-N-DMTr-morpholino-5-methylcytosine-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-154705

*N-DMTr-Morpholino-U-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-DMTr-Morpholino-U-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154706

*N-DMTr-Morpholino-T-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-DMTr-Morpholino-T-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039425

*N-Trityl-morpholino-T-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-Trityl-morpholino-T-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-152970

*7'-O-DMT-morpholino* uracil**	Nucleoside Antimetabolite/Analog	Others
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-W048487

*N6-Benzoyl-7’-OH-morpholino* adenine** N6-Benzoyl-7'-OH-morpholino adenosine	Nucleoside Antimetabolite/Analog	Cancer
N6-Benzoyl-7’-OH-morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154708

*N-DMTr-N6-Benzoyl-morpholino-A-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-DMTr-N6-Benzoyl-morpholino-A-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039428

*N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154707

*N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-DMTr-N4-Benzoyl-morpholino-cytosine-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154709

*N-DMTr-N2-Isobutyryl-morpholino-G-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-DMTr-N2-Isobutyryl-morpholino-G-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039426

*N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039427

*N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite*	DNA/RNA Synthesis	Others
N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-152973

*7'-O-DMT-morpholino* thymine**	Nucleoside Antimetabolite/Analog	Others
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-152984

*N6-Benzoyl-7'-O-DMT-morpholino* adenine**	Nucleoside Antimetabolite/Analog	Others
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-132586

Viltolarsen NS-065/NCNP-01	Nucleoside Antimetabolite/Analog	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-W357200

*N6-Benzoyl-7’-OH-N-trityl morpholino* adenine** N-[9-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-9H-purin-6-yl]-benzamide	Nucleoside Antimetabolite/Analog	Cancer
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W357201

*N4-Benzoyl-7’-OH-N-trityl morpholino* cytosine** N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide	Nucleoside Antimetabolite/Analog	Cancer
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium	Nucleoside Antimetabolite/Analog	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-W127629

MOBS	Biochemical Assay Reagents	Others
MOBS is an amphoteric buffer, a butane analogue of the Good buffers MOPS [3-(N-morpholino) propanesulfonic acid] and MES [2-(N-morpholino) ethanesulfonic acid] .

HY-109633A

PI3K-IN-18 dihydrochloride	PI3K	Others
PI3K-IN-18 (Compound 1) dihydrochloride is a 4-morpholino-2-phenylquinazoline derivative and an inhibitor of PI3K p110α .

HY-132611A

Golodirsen sodium SRP-4053 sodium	Arp2/3 Complex	Others
Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132611

Golodirsen SRP-4053	Arp2/3 Complex	Others
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132584A

Casimersen sodium SRP-4045 sodium	Arp2/3 Complex	Others
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132584

Casimersen SRP-4045	Arp2/3 Complex	Others
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-P10559

(RXR)4XB	Bacterial	Infection
(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC₅₀ of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .

HY-12379

NS-2028	Guanylate Cyclase	Inflammation/Immunology
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC₅₀ values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity . NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase with IC₅₀ values of 17 nM and 20 nM . NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells with an IC₅₀ of 30 nM . NS-2028 is commonly used in the research of nitric oxide signaling pathways, it inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM) . NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability .

MOBS	Biochemical Assay Reagents
MOBS is an amphoteric buffer, a butane analogue of the Good buffers MOPS [3-(N-morpholino) propanesulfonic acid] and MES [2-(N-morpholino) ethanesulfonic acid] .

*1-Deoxy-1-morpholino-D-fructose*	Carbohydrates
1-Deoxy-1-morpholino-D-fructose can be used in sugar science research.

Cat. No.	Product Name	Target	Research Area

HY-P10559

(RXR)4XB	Bacterial	Infection
(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC₅₀ of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .

HY-P10567

Pip6a	Peptides	Others
Pip6a is an arginine-rich cell-penetrating peptide. Pip6a has the ability to deliver associated cargoes across the plasma and endosomal membranes and is stable to serum proteolysis. Pip6a is composed of a hydrophobic core region flanked on each side by arginine-rich domains containing β-alanine and aminohexanoyl spacers. Pip6a-conjugated morpholino phosphorodiamidate oligomer (PMO) dramatically enhanced antisense oligonucleotide (ASO) delivery into striated muscles of myotonic dystrophy (DM1) mice .

Cat. No.	Product Name		Classification

HY-154665

*N4-Benzoyl-N-DMTr-morpholino-5-methylcytosine-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-154705

*N-DMTr-Morpholino-U-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-DMTr-Morpholino-U-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154706

*N-DMTr-Morpholino-T-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-DMTr-Morpholino-T-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039425

*N-Trityl-morpholino-T-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-Trityl-morpholino-T-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-152970

*7'-O-DMT-morpholino* uracil**		Nucleosides and their Analogs
7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154708

*N-DMTr-N6-Benzoyl-morpholino-A-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-DMTr-N6-Benzoyl-morpholino-A-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039428

*N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154707

*N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite*		Nucleoside Phosphoramidites
N-DMTr-N4-Benzoyl-morpholino-cytosine-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-154709

*N-DMTr-N2-Isobutyryl-morpholino-G-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-DMTr-N2-Isobutyryl-morpholino-G-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039426

*N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W039427

*N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite*		Nucleoside Phosphoramidites
N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-152973

*7'-O-DMT-morpholino* thymine**		Nucleosides and their Analogs
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-132585A

SRP-5051 sodium Vesleteplirsen sodium		Antisense Oligonucleotides
SRP-5051 sodium is a next-generation antisense oligonucleotide of peptide phosphorodiamidate morpholino oligomer (PPMO). SRP-5051 targeting exon 51 skipping in Duchenne muscular dystrophy (DMD) .

HY-152984

*N6-Benzoyl-7'-O-DMT-morpholino* adenine**		Nucleosides and their Analogs
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-132586

Viltolarsen NS-065/NCNP-01		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132611A

Golodirsen sodium SRP-4053 sodium		Antisense Oligonucleotides
Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132611

Golodirsen SRP-4053		Antisense Oligonucleotides
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132584A

Casimersen sodium SRP-4045 sodium		Antisense Oligonucleotides
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132584

Casimersen SRP-4045		Antisense Oligonucleotides
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .

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