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Results for "

non-classical

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Peptides

2

Inhibitory Antibodies

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1500
    2,2,2-Trichloroethanol

    		Potassium Channel Endogenous Metabolite Neurological Disease
    2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4) .
    2,2,2-Trichloroethanol
  • HY-107981
    LSN 3213128
    1 Publications Verification

    		 Antifolate Cancer
    LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity .
    LSN 3213128
  • HY-114719
    A 854777

    		Endogenous Metabolite Inflammation/Immunology
    A 854777 is a homologous piperazine derivative with anti-inflammatory activity. A 854777 has non-classical immunosuppressive properties. A 854777 can be used to suppress diseases associated with inflammation .
    A 854777
  • HY-146753
    HIV-1 inhibitor-20

    		HIV Infection
    HIV-1 inhibitor-20 is a potent HIV-1 inhibitor by non-classical isosteric replacement of amide to 1,2,4-oxadiazoles .
    HIV-1 inhibitor-20
  • HY-163399
    Antibacterial agent 197

    		Bacterial Infection
    Antibacterial agent 197 (compound 1-deAA) is a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan (PG) in bacterial TGase, with activity against Staphylococcus aureus. Antibacterial agent 197 synergizes with Vancomycin (HY-B0671) and is its antibacterial adjuvant .
    Antibacterial agent 197
  • HY-B1500R
    2,2,2-Trichloroethanol (Standard)

    		Potassium Channel Endogenous Metabolite Neurological Disease
    2,2,2-Trichloroethanol (Standard) is the analytical standard of 2,2,2-Trichloroethanol. This product is intended for research and analytical applications. 2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4) .
    2,2,2-Trichloroethanol (Standard)
  • HY-P10669
    NDI-Lyso

    		Caspase Apoptosis Cancer
    NDI-Lyso is a lysosome-targeted anticancer agent that induces the formation of rigid long fibers in cancer cell lysosomes through an enzyme-instructed self-assembly (EISA) mechanism catalyzed by cathepsin B. This process triggers lysosomal swelling, membrane permeabilization (LMP), and membrane disruption, ultimately leading to cancer cell apoptosis via a non-classical caspase-independent pathway. NDI-Lyso exhibits significant selective anticancer activity in various cancer cell lines and drug-resistant cancer cells (IC50 ~10 μM) while showing low toxicity to normal cells (IC50 > 60 μM) .
    NDI-Lyso

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