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oxidation sensitive

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Biochemical Assay Reagents (2) Drug Metabolite (1) Guanylate Cyclase (1) Keap1-Nrf2 (1) Liposome (1) Parasite (1)
By Research Areas:	Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Oligonucleotides

Targets Recommended: VAP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine	Liposome	Others
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

HY-78237

Nelociguat 1 Publications Verification BAY60-4552	Guanylate Cyclase	Cardiovascular Disease
Nelociguat (BAY60-4552) is a nitric oxide sensitive soluble guanylate cyclase stimulator.

HY-W106746

Sodium bismuthate dihydrate, 85% Bismuth sodium oxide dihydrate, 85%	Biochemical Assay Reagents	Others
Sodium bismuthate dihydrate, 85% (Bismuth sodium oxide dihydrate, 85%) is a sensitive colorimetric reagent for the determination of monoamines. Sodium bismuthate dihydrate, 85% is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W094505

Sodium bismuthate (NaBiO3), 80% Bismuth sodium oxide, 80%	Biochemical Assay Reagents	Others
Sodium bismuthate (NaBiO3), 80% (Bismuth sodium oxide, 80%) is a sensitive colorimetric reagent for the determination of monoamines. Sodium bismuthate (NaBiO3), 80% is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W099331

Monoethylglycinexylidide hydrochloride MEGX hydrochloride; Norlidocaine hydrochloride	Drug Metabolite	Metabolic Disease Inflammation/Immunology
Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation .

HY-137119A

8,12-iso-iPF2α-VI	Others	Others
8,12-iso-iPF2α-VI is a F2-isoprostanes. 8,12-iso-iPF2α-VI is a sensitive and specific marker of in vivo lipid peroxidation. 8,12-iso-iPF2α-VI can be used as a biomarker of oxidative damage in alzheimer's disease .

HY-149246

Aβ-IN-6	Amyloid-β Keap1-Nrf2	Neurological Disease Inflammation/Immunology
Aβ-IN-6 reduces pro-inflammatory cytokine release from microglia cells. Aβ-IN-6 significantly induces Nrf2 nuclear translocation and hamperes Aβ oligomers formation. Aβ-IN-6 exerts a consistent neuroprotective effect by modulating the redox-sensitive signalling pathways in vivo oxidative stress model. Aβ-IN-6 is an orally active and has antiinflammatory, Antioxidant and Anti-oligomeric activity. Aβ-IN-6 has the potential for Alzheimer's disease (AD) research .

HY-138074

Milbemycin A4 oxime 5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime	Parasite	Infection
Milbemycin A4 oxime is a derivative of milbemycin A4 (Item No. 17155) and a component of Milbemycin Oxime (HY-B0778), compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae of the heartworm D. immitis in naturally infested dogs. It inhibits the growth of clinical isolates of C. glabrata with MIC80 values ranging from 16 to greater than 32 μg/mL.1 Milbemycin A4 oxime (2.5 μg/mL) blocks efflux of Fluconazole (HY-B0101) from a clinical isolate of C. glabrata, but not from a strain lacking the efflux pumps CgCDR1 and PDH1, and reduces the MICs of fluconazole and 4-nitroquinoline 1-oxide in wild-type C. glabrata. It enhances adriamycin-induced inhibition of cell growth, as well as increases the intracellular accumulation of adriamycin and the P-glycoprotein substrate Rhodamine 123 (HY-D0816), in adriamycin-resistant, but not -sensitive, MCF-7 breast cancer cells in a concentration-dependent manner.

Cat. No.	Product Name	Type

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine	Drug Delivery
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

Drug Delivery

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

HY-W106746

Sodium bismuthate dihydrate, 85% Bismuth sodium oxide dihydrate, 85%	Indicators
Sodium bismuthate dihydrate, 85% (Bismuth sodium oxide dihydrate, 85%) is a sensitive colorimetric reagent for the determination of monoamines. Sodium bismuthate dihydrate, 85% is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W094505

Sodium bismuthate (NaBiO3), 80% Bismuth sodium oxide, 80%	Indicators
Sodium bismuthate (NaBiO3), 80% (Bismuth sodium oxide, 80%) is a sensitive colorimetric reagent for the determination of monoamines. Sodium bismuthate (NaBiO3), 80% is a kind of biological materials or organic compounds that are widely used in life science research .

Cat. No.	Product Name		Classification

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine		Phospholipids
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

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