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pediatric

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (4) Antibiotic (1) Antifolate (2) Bacterial (1) Endogenous Metabolite (2) HDAC (1) Isotope-Labeled Compounds (1) Potassium Channel (4)
By Research Areas:	Cancer (5) Cardiovascular Disease (5) Endocrinology (1) Infection (1) Inflammation/Immunology (2) Neurological Disease (3)

11

Inhibitors & Agonists

1

Inhibitory Antibodies

3

Natural
Products

2

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Sotalol hydrochloride 2 Publications Verification MJ 1999	Adrenergic Receptor Potassium Channel	Cardiovascular Disease Neurological Disease
Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent .

Sulfamoxole	Bacterial Antibiotic	Infection
Sulfamoxole is a broad- spectrum chemotherapeutic antimicrobial agent. Sulfamoxole can be used for the study of pediatric infections .

N-Acetyl-L-arginine 1 Publications Verification Ac-Arg-OH	Endogenous Metabolite	Others
N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population.

Aminopterin 4-Aminofolic acid; APGA	Antifolate	Inflammation/Immunology Cancer
Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a K_i of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .

Sotalol-d6 hydrochloride MJ 1999-d₆ hydrochloride	Adrenergic Receptor Potassium Channel	Cardiovascular Disease Endocrinology
Sotalol-d₆ (hydrochloride) is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels[1][2].

Indicine N-oxide (+)-Indicine N-oxide; NSC 132319	Others	Cancer
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .

Sotalol	Adrenergic Receptor Potassium Channel	Cardiovascular Disease Neurological Disease
Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent .

CE(16:1(9Z)) 16:1(9Z) CE; 16:1(9Z) Cholesterol ester; Cholesterol Palmitoleate	Endogenous Metabolite	Cardiovascular Disease
Cholesteryl palmitoleate is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE-/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.

Sotalol-d6 MJ 1999-d₆	Isotope-Labeled Compounds Adrenergic Receptor Potassium Channel	Cardiovascular Disease Neurological Disease
Sotalol-d₆ is the deuterium labeled Sotalol. Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3][4].

Aminopterin (Standard)	Antifolate	Inflammation/Immunology Cancer
Aminopterin (Standard) is the analytical standard of Aminopterin. This product is intended for research and analytical applications. Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .

NN-390	HDAC	Cancer
NN-390 is a potent and selective HDAC6 inhibitor, with an IC₅₀ of 9.8 nM. NN-390 penetrates the blood-brain barrier (BBB). NN-390 shows study potential in metastatic Group 3 MB (medulloblastoma) .

Cat. No.	Product Name	Target	Research Area

Dinutuximab Unituxin; APN-311	Inhibitory Antibodies	Cancer
Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]) .

Cat. No.	Product Name	Category	Target	Chemical Structure

N-Acetyl-L-arginine 1 Publications Verification Ac-Arg-OH	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population.

Dinutuximab Unituxin; APN-311	Classification of Application Fields Disease Research Fields Cancer	Others
Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]) .

Indicine N-oxide (+)-Indicine N-oxide; NSC 132319	Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Tournefortia argentea Linnaeus f. Source classification Plants Disease Research Fields Boraginaceae Cancer	Others
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .

Cat. No.	Product Name	Chemical Structure

Sotalol-d6 hydrochloride
Sotalol-d₆ (hydrochloride) is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels[1][2].

Sotalol-d6
Sotalol-d₆ is the deuterium labeled Sotalol. Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3][4].

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