phenolic metabolites

By Targets:	Drug Metabolite (1) Endogenous Metabolite (5) Apoptosis (2) Isotope-Labeled Compounds (2) TNF Receptor (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Metabolic Disease (1)

Targets Recommended: Drug Metabolite Endogenous Metabolite

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119983

7H-Dibenzo[c,g]carbazole DBC	Others	Cancer
7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites .

HY-W015752

5-Methoxyresorcinol	Endogenous Metabolite	Others
5-Methoxyresorcinol is a member of the resorcinol family, which is phloroglucinol, in which phenol hydrogen is replaced by a methyl group. It has the function of a metabolite of brassica napus. 5-Methoxyresorcinol inhibits protein synthesis .

HY-N7513

Homovanillyl alcohol	TNF Receptor Drug Metabolite	Cardiovascular Disease
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease .

HY-162297

4-(Sulfooxy)benzoic acid	Others	Others
4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids .

HY-125909

Phenolic acid	Endogenous Metabolite	Metabolic Disease
Phenolic acid is an endogenous metabolite.

HY-118247

Ro 14-6113	Others	Others
Ro 14-6113 is an inactive phenolic metabolite of the "carotenoid" Ro 15-0778, a form of vitamin A.

HY-W020576S

Rivastigmine metabolite-d6 NAP 226-90-d₆	Isotope-Labeled Compounds	Others
(S)-3-(1-(Dimethylamino)ethyl)phenol-d6 is the deuterium labeled Rivastigmine metabolite(HY-W020576) .

HY-W844141

2,5-Dimethylchroman-4-one	Others	Others
2,5-Dimethylchroman-4-one is a Phenols product that can be isolated from the metabolites of Alternaria brassicicola ML-P08. .

HY-153993

Pyrocatechol sulfate	Endogenous Metabolite	Others
Pyrocatechol sulfate, a phenolic metabolite present in human plasma, is associated with the consumption of specific foods such as berries and the condition of gut microbiota. It serves as a potential urinary biomarker for kidney function, dialytic clearance, whole grain consumption, and regular coffee intake. Additionally, Pyrocatechol sulfate, along with other phenolic sulfates, plays a role in modulating various biological functions, including those related to brain health and the rhythmic beating of cardiomyocytes.

HY-108692

Enterolactone	Apoptosis Endogenous Metabolite	Cancer
Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity . Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis .

HY-108692S

Enterolactone-d6	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Cancer
Enterolactone-d₆ is the deuterium labeled Enterolactone. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity[1]. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis[2].

Cat. No.	Product Name

HY-L021

Natural Product Library	4,689 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery. Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored. MCE provides a unique collection of 4,689 natural compounds that contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Natural Product Library

4,689 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery.

Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored.

MCE provides a unique collection of 4,689 natural compounds that contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L021P

Natural Product Library Plus	5,540 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery. Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored. MCE provides a unique collection of 5,540 natural compounds that contains Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library Plus, with more powerful screening capability, further complements Natural Product Library (HY-L021) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

Natural Product Library Plus

5,540 compounds