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post-menopausal osteoporosis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (3) CaSR (2) Drug Metabolite (1) Estrogen Receptor/ERR (7) Progesterone Receptor (2) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (5) Endocrinology (10) Inflammation/Immunology (2) Metabolic Disease (4)
Click Chemistry:	Alkynes (1)

15

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3

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1

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

2''-O-Rhamnosylicariside II	Others	Others
2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.

Tibolone	Progesterone Receptor Androgen Receptor Estrogen Receptor/ERR	Endocrinology
Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research .

Alendronic acid 5 Publications Verification	Others	Cancer
Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease .

LY88074 analog 1	Others	Endocrinology
LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .

LGD-2941	Androgen Receptor	Endocrinology
LGD-2941 is an orally active, potent and selective androgen receptor modulator. LGD-2941 shows excellent anabolic activity in muscle with reduced effect on the prostate in a rat model of hypogonadism. LGD-2941 also improves bone strength in a rat model of post-menopausal osteoporosis .

Nilestriol Nylestriol; EE3CPE	Estrogen Receptor/ERR	Endocrinology
Nilestriol is a estriol derivative, which inhibits osteoporosis on ovariectomized rats or postmenopausal women .

Alendronate sodium Alendronic acid monosodium salt	Others	Metabolic Disease Cancer
Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis .

6-Raloxifene-β-D-glucopyranoside	Estrogen Receptor/ERR Drug Metabolite	Metabolic Disease
6-Raloxifene-β-D-glucopyranoside, a derivative of Raloxifene, is a benzothiophene glucuronidated at the 6' postion. 6-Raloxifene-β-D-glucopyranoside is a selective and orally active estrogen receptor antagonist. 6-Raloxifene-β-D-glucopyranoside can be used for inhibiting bone loss and resorption, and lowering lipid levels. 6'-Raloxifene-β-D-glucopyranoside, compound Ia, is extracted from patent US5567820A .

Levormeloxifene L-Centchroman; L-Ormeloxifene	Estrogen Receptor/ERR	Endocrinology Cancer
Levormeloxifene (L-Centchroman) is a selective estrogen receptor modulator (SERM), which prevents and ameliorates postmenopausal osteoporosis. Levormeloxifene causes multiple adverse gynecological effects .

Ronacaleret SB 751689	CaSR	Metabolic Disease Endocrinology
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .

Ronacaleret hydrochloride SB 751689A	CaSR	Metabolic Disease Endocrinology
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .

Tibolone (Standard)	Progesterone Receptor Androgen Receptor Estrogen Receptor/ERR	Endocrinology
Tibolone (Standard) is the analytical standard of Tibolone. This product is intended for research and analytical applications. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research .

pTH-Related Protein (1-34) (human,mouse,rat) pTHrP (1-34)	Thyroid Hormone Receptor	Inflammation/Immunology
pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study .

Lasofoxifene 4 Publications Verification CP-336156	Estrogen Receptor/ERR	Inflammation/Immunology Cancer
Lasofoxifene (CP-336156) is an orally active and selective estrogen receptor modulator (SERM). Lasofoxifene exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene can be used for research of breast cancer and postmenopausal osteoporosis .

Lasofoxifene tartrate 4 Publications Verification CP-336156 tartrate	Estrogen Receptor/ERR	Endocrinology Cancer
Lasofoxifene (CP-336156) tartrate is an orally active and selective estrogen receptor modulator (SERM) . Lasofoxifene tartrate exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene tartrate can be used for the research of breast cancer and postmenopausal osteoporosis .

Cat. No.	Product Name	Target	Research Area

Calcitonin, eel TFA Thyrocalcitonin eel TFA	Peptides	Others
Calcitonin, eel TFA is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis .

pTH-Related Protein (1-34) (human,mouse,rat) pTHrP (1-34)	Thyroid Hormone Receptor	Inflammation/Immunology
pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study .

Calcitonin, eel Thyrocalcitonin eel	Peptides	Endocrinology
Calcitonin, eel is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis.

Cat. No.	Product Name		Classification

Nilestriol Nylestriol; EE3CPE		Alkynes
Nilestriol is a estriol derivative, which inhibits osteoporosis on ovariectomized rats or postmenopausal women .

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