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repeats

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Amyloid-β (2) Apoptosis (3) Autophagy (2) DNA/RNA Synthesis (4) E1/E2/E3 Enzyme (1) Epigenetic Reader Domain (1) Glyoxalase (GLO) (1) Histone Methyltransferase (13) HIV (1) HSP (1) IKK (2) Ligands for Target Protein for PROTAC (2) LRRK2 (11) Notch (1) PROTACs (4) Ser/Thr Protease (2) Tau Protein (5) Toll-like Receptor (TLR) (7)
By Research Areas:	Cancer (27) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (12) Neurological Disease (21)
Oligonucleotides:	CpG ODNs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141799

Dimethyl-F-OICR-9429-COOH	Ligands for Target Protein for PROTAC	Cancer
Dimethyl-F-OICR-9429-COOH a ligand for WD40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1 intermediate 19. Dimethyl-F-OICR-9429-COOH can be used in the synthesis of PROTACs .

HY-129087

BC-1258	Apoptosis	Cancer
BC-1258, an *F-box/LRR-repeat* protein 2 (FBXL2)** activator, can stabilize and upregulate FBXL2 levels. BC-1258 induces apoptosis of tumorigenic cells, and profoundly inhibits tumor formation in mice .

HY-19820A

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of *pleckstrin homology domain and leucine-rich repeat* protein phosphatase (PHLPP)**. NSC45586 sodium targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

HY-150400

XF056-132 free base	PROTACs Histone Methyltransferase	Cancer
XF056-132 free base is a potent WDR5 (WD40 repeat domain protein 5) PROTAC degrader .

HY-157332

WDR5-IN-7	Histone Methyltransferase	Cancer
WDR5-IN-7 (Compound 22) is an orally bioavailable benzoxazepinone-based WD repeat domain 5 (WDR5) inhibitor. WDR5-IN-7 can be used for the research of anti-cancer .

HY-163941

GSK_WRN2	DNA/RNA Synthesis	Cancer
GSK_WRN2 is a potent and selective covalent WRN helicase inhibitor that suppresses replication stress caused by DNA (TA)_n dinucleotide repeat expansions. GSK_WRN2 can be used to study microsatellite instability (MSI) cancers .

HY-141798

OICR-9429-N-C2-NH2	Ligands for Target Protein for PROTAC	Cancer
OICR-9429-N-C2-NH2 is a ligand for *Wd40 repeat* domain protein 5 (WDR5)** extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs .

HY-P10636

Nictide	LRRK2	Others
Nictide is a peptide substrate of LRRK2 (leucine-rich repeat protein kinase-2). Nictide can be phosphorylated by the activated LRRK2[G2019S] with a Km of 10 μM .

HY-19820

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of *pleckstrin homology domain and leucine-rich repeat* protein phosphatase (PHLPP)**. NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

HY-148353

PF-06455943	LRRK2	Neurological Disease
PF-06455943 is a *leucine rich repeat* kinase 2 (LRRK2) inhibitor with IC₅₀** value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD) .

HY-16993

OICR-9429 5+ Cited Publications	Histone Methyltransferase Apoptosis	Cancer
OICR-9429 is high affinity *WD repeat* domain 5 (WDR5)** inhibitor, competitively blocks WDR5 interaction with MLL protein via binding the central peptide-binding pocket of WDR5. OICR-9429 can suppress histone H3K4 trimethylation and can be used for the research of various cancers including non-MLL-rearranged leukaemia, colon, pancreatic, prostate cancer and bladder cancer (BCa) .

HY-P2516

*Tau Peptide (275-305) (Repeat* 2 domain)**	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P4924

*Tau Peptide (244-274) (Repeat* 1 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (244-274) (Repeat 1 Domain) is aTau fragment.

HY-P4927

*Tau Peptide (245-274) (Repeat* 1 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (245-274) (Repeat 1 Domain) is aTau fragment.

HY-P4966

*Tau Peptide (306-336) (Repeat* 3 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (306-336) (Repeat 3 Domain) is aTau fragment.

HY-19347

WDR5-0103 WD-Repeat Protein 5-0103	Histone Methyltransferase	Cancer
WDR5-0103 is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist with Kd of 450 nM.

HY-134562

PF-06371900	LRRK2	Neurological Disease
PF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor .

HY-N4192

Toringin	Others	Cardiovascular Disease Cancer
Toringin, a bioflavonoid, is isolated from the bark of Docyniopsis tschonoski. Toringin progressively decreases not only the cis-effect of the expanded CTG repeats but cytotoxicity as well. Exposure to isosakuranetin, Toringin rescues PC12 neuronal cells. Flavonoids are efficacious for ameliorating the RNA gain of function caused by expanded CTG repeats, and have various biological activities and beneficial actions against cancers, coronary heart disease, among other pathologies .

HY-P1896

Hsp70-derived octapeptide	HSP	Infection Neurological Disease Cancer
Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs .

HY-150403

XF067-68	PROTACs Histone Methyltransferase	Cancer
XF067-68 is a PROTAC for targeted degradation of WD40 repeat domain protein 5 (WDR5) (extracted from patent WO2019246570A1) .

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-160228

ORN 02	Toll-like Receptor (TLR)	Inflammation/Immunology
ORN 02 is a synthetic single-stranded U-rich RNA and contains 6 repeats of UUAU sequence motif. The AU-rich oligoribonucleotides (ORNs) are able to stimulate TLR8 .

HY-160228A

ORN 02 sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
ORN 02 (sodium) is a synthetic single-stranded U-rich RNA and contains 6 repeats of UUAU sequence motif. The AU-rich oligoribonucleotides (ORNs) are able to stimulate TLR8 .

HY-160227A

ORN 06 sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
ORN 06 (sodium) s a synthetic single-stranded U-rich RNA and contains 6 repeats of the UUGU sequence motif. The GU-rich oligoribonucleotides (ORNs) are able to stimulate TLR7 .

HY-141482

WSB1 Degrader 1	E1/E2/E3 Enzyme	Cancer
WSB1 Degrader 1 is a poten and orally active *WSB1 (WD repeat* and SOCS box-containing 1)** degrader. WSB1 Degrader 1 has anticancer metastatic effects .

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-120085

PFE-360 2 Publications Verification PF-06685360	LRRK2	Neurological Disease
PFE-360 (PF-06685360) is a potent, selective, brain penetrated and orally active *leucine-rich repeat* kinase 2 (LRRK2) inhibitor with a mean IC₅₀** of 2.3 nM in vivo .

HY-141878

di-Ellipticine-RIBOTAC	PROTACs	Neurological Disease
di-Ellipticine-RIBOTAC is a dual-function small molecule that reduces c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo amyotrophic lateral sclerosis (ALS ) models.

HY-15839

UNC 669 2 Publications Verification	Epigenetic Reader Domain	Cancer
UNC 669, a ligand for a methyl-lysine binding domain, is a potent L3MBTL1 (IC₅₀=4.2 uM) and L3MBTL3 (3.1 uM) inhibitor .

HY-141796

MS67	Histone Methyltransferase PROTACs	Cancer
MS67 is a potent and selective *WD40 repeat* domain protein 5 (WDR5) degrader with a K_d** of 63 nM. MS67 is inactive against other protein methyltransferases, kinases, GPCRs, ion channels, and transporters. MS67 shows potent acticancer effects .

HY-144074

LRRK2-IN-4	LRRK2	Neurological Disease
LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active *leucine-rich repeat* kinase 2 (LRRK2) inhobitor with an IC₅₀** of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease .

HY-160229

ssRNA40 sodium R-1075 sodium	Toll-like Receptor (TLR)	Infection
ssRNA40 (sodium) is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. ssRNA40 is a uridine-rich ssRNA derived from the HIV-1 long terminal repeat on activation of NK cells via TLR7/8 ^[1][2].

HY-13687

IKK 16 Maximum Cited Publications 16 Publications Verification	IKK LRRK2	Inflammation/Immunology
IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC₅₀s of 40 nM, 70 nM and 200 nM, respectively. IKK16 also inhibits leucine-rich repeat kinase-2 (LRRK2) with an IC₅₀ of 50 nM.

HY-13687A

IKK 16 hydrochloride Maximum Cited Publications 16 Publications Verification	IKK LRRK2	Inflammation/Immunology
IKK 16 hydrochloride is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC₅₀s of 40 nM, 70 nM and 200 nM, respectively . IKK16 also inhibits leucine-rich repeat kinase-2 (LRRK2) with an IC₅₀ of 50 nM .

HY-12282

GNE-9605	LRRK2	Neurological Disease
GNE-9605 is a potent, orally active, selective *Leucine-rich repeat* kinase 2 (LRRK2) inhibitor with an IC₅₀** value of 18.7 nM. GNE-9605 inhibits LRRK2 Ser1292 autophosphorylation. GNE-9605 can be used in research of Parkinson's disease (PD) .

HY-P4933

*Tau Peptide (255-314) (Repeat* 2 Domain) (human)**	Tau Protein	Others
Tau Peptide (255-314) (Repeat 2 Domain) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-100869

MM-589	Histone Methyltransferase	Cancer
MM-589 is a potent inhibitor of *WD repeat* domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC₅₀ of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC₅₀** of 12.7 nM .

HY-124824

Methyl gerfelin	Glyoxalase (GLO)	Others
Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: *glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat* containing protein A (SGTA). Methyl gerfelin is a potent GLO1** inhibitor related to the flavonoid class .

HY-163942

GSK_WRN4	DNA/RNA Synthesis	Cancer
GSK_WRN4 is a WRN helicase inhibitor (pIC₅₀=7.6) with anticancer activity. GSK_WRN4 selectively inhibits the growth of MSI tumor cells in vitro and in vivo by inducing DNA double-strand breaks, particularly at expanded TA repeats and DNA damage regions .

HY-100869A

MM-589 TFA	Histone Methyltransferase	Cancer
MM-589 TFA is a potent inhibitor of *WD repeat* domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC₅₀ of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC₅₀** of 12.7 nM .

HY-160227

ORN 06	Toll-like Receptor (TLR)	Inflammation/Immunology
ORN 06 (Compound R-0006), a U-rich single-stranded RNA (containing 6 repeats of the UUG sequence motif), is a TLR7/8 agonist. ORN 06 stimulates human TLR7/8-mediated or murine TLR7-mediated immunity .

HY-111753

WDR5-IN-4 3 Publications Verification	Histone Methyltransferase	Cancer
WDR5-IN-4 is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a K_d of 0.1 nM. WDR5-IN-4 displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity .

HY-P1985A

Notch 1 TFA	Notch	Cardiovascular Disease Cancer
Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types .

HY-111753A

WDR5-IN-4 TFA 3 Publications Verification	Histone Methyltransferase	Cancer
WDR5-IN-4 TFA is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a K_d of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity .

HY-150654

WDR5-IN-5	Histone Methyltransferase	Cancer
WDR5-IN-5 is an orally active and selective inhibitor of WIN site of *WD repeat* domain 5 (WDR5). WDR5-IN-5 exhibits anti-proliferative activity towards cancer cells and good pharmacokinetics profile in mice. WDR5-IN-5 shows high affinity to WDR5** and the binding affinity K_i value <0.02 nM .

HY-P5497

C34 peptide	HIV	Others
C34 peptide is a biological active peptide. (This C34 peptide, also known as HR2, belongs to the helical region of gp41 of HIV, C-terminal heptad repeat 2 (HR2) defined as C helix or C peptide. It is known that HIV-1 enters cells by membrane fusion, C34 gp41 peptide is a potent inhibitors of HIV-1 fusion.)

HY-153898

rTRD01	Others	Neurological Disease
rTRD01 is a TDP-43 ligand that binds to TDP-43’s RRM1 and RRM2 domains (K_d=89 uM for TDP-43_102–269). rTRD01 partially disrupts TDP-43’s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases .

HY-100869B

MM-589 (racemic mixture ) (TFA)	Histone Methyltransferase	Cancer
MM-589 (racemic mixture) TFA, is a racemic mixture of MM-589 TFA (HY-100869A). MM-589 TFA is a potent inhibitor of *WD repeat* domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC₅₀ of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC₅₀** of 12.7 nM .

HY-151441

LRRK2-IN-5	LRRK2	Neurological Disease
LRRK2-IN-5 (compound 25) is a potent, orally active, selective *leucine rich repeat* protein kinase 2 gene (LRRK2) inhibitor with IC₅₀** values of 1.2 and 16 μM for GS LRRK2 and WT LRRK2, respectively. LRRK2-IN-5 inhibits LRRK2 Ser1292 and Ser925 autophosphorylation. LRRK2-IN-5 can cross the blood-brain barrier .

HY-151444

LRRK2-IN-6	LRRK2	Neurological Disease
LRRK2-IN-6 (compound 22) is a potent, orally active, selective *leucine rich repeat* protein kinase 2 gene (LRRK2) inhibitor with IC₅₀** values of 4.6 and 49 μM for GS LRRK2 and WT LRRK2, respectively. LRRK2-IN-6 inhibits LRRK2 Ser1292 and Ser925 autophosphorylation. LRRK2-IN-6 can cross the blood-brain barrier .

Cat. No.	Product Name	Type

HY-D1056C3

Lipopolysaccharides, from S. enterica serotype typhimurium

LPS, from Salmonella enterica (Serotype typhimurium)

Carbohydrates

Lipopolysaccharides, from S. enterica serotype typhimurium, are a kind of lipid-polysaccharide endotoxin. Smooth Gram-negative bacteria's lipopolysaccharides are made up of three components: lipid A, core oligosaccharide, and O antigen (OAg). The O antigen is a polymer of sugar repeat units (RUs); the Wzz protein regulates the length of the O antigen in lipopolysaccharides, and the number of RUs attached to lipid A is determined by the modal value set by the Wzz protein. S. enterica typhimurium has two Wzz proteins: Wzz_ST (which makes the modal range of the O antigen between 16 and 35 RUs) and Wzz_fepE (which makes the modal value over 100 RUs). Mutating the genes corresponding to these two proteins causes the formation of short-chain O antigen chains and significantly reduces bacterial pathogenicity .

HY-D1056C2

Lipopolysaccharides, from S. enterica serotype minnesota

LPS, from Salmonella enterica (Serotype minnesota)

Carbohydrates

Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Cat. No.	Product Name	Target	Research Area

HY-P2516

*Tau Peptide (275-305) (Repeat* 2 domain)**	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P10100

*RS Repeat* peptide**	Peptides	Others
RS Repeat peptide is a substrate peptide for Clk1 .

HY-P1896

Hsp70-derived octapeptide	HSP	Infection Neurological Disease Cancer
Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs .

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P10636

Nictide	LRRK2	Others
Nictide is a peptide substrate of LRRK2 (leucine-rich repeat protein kinase-2). Nictide can be phosphorylated by the activated LRRK2[G2019S] with a Km of 10 μM .

HY-P4924

*Tau Peptide (244-274) (Repeat* 1 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (244-274) (Repeat 1 Domain) is aTau fragment.

HY-P4927

*Tau Peptide (245-274) (Repeat* 1 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (245-274) (Repeat 1 Domain) is aTau fragment.

HY-P4966

*Tau Peptide (306-336) (Repeat* 3 Domain)**	Tau Protein	Neurological Disease
Tau Peptide (306-336) (Repeat 3 Domain) is aTau fragment.

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P1917

Uty HY Peptide (246-254)	Peptides	Inflammation/Immunology
Uty HY Peptide (246-254), derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YD ^b, is a male-specific transplantation antigen H-Y .

HY-P1917A

Uty HY Peptide (246-254) (TFA)	Peptides	Inflammation/Immunology
Uty HY Peptide (246-254) TFA, derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YD ^b, is a male-specific transplantation antigen H-Y .

HY-P10434

BRC4wt BRC4 repeat motif	Peptides	Cancer
BRC4wt (BRC4 repeat motif) is part of the BRACA2 tumor suppressor protein, which exhibits inhibitory activity against interaction of the BRACA2 protein with RAD51, and is involved in the repair of DNA damage .

HY-P0319

3X FLAG peptide 5+ Cited Publications	Peptides	Others
3X FLAG peptides are FLAG-tagged peptides containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide can be used for protein separation and purification, and competitive elution with target proteins.

HY-P0319A

3X FLAG peptide TFA 5+ Cited Publications	Peptides	Others
3X FLAG peptide TFA is a FLAG-tagged peptide containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide TFA can be used for protein separation and purification, and competitive elution with target proteins.

HY-P1861

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)	Peptides	Inflammation/Immunology
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP), a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU) .

HY-P1861A

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA)	Peptides	Inflammation/Immunology
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA, a 20-residue peptide and a major pathogenic epitope, is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP 161–180), which can induce posterior uveitis (EAU) .

HY-P4968

*Tau Peptide (337-368) (Repeat* 4 Domain)**	Peptides	Others
Tau Peptide (337-368) (Repeat 4 Domain) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4830

*Acetyl-Tau Peptide (244-274) (Repeat* 1 Domain)**	Peptides	Others
Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4933

*Tau Peptide (255-314) (Repeat* 2 Domain) (human)**	Tau Protein	Others
Tau Peptide (255-314) (Repeat 2 Domain) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1985A

Notch 1 TFA	Notch	Cardiovascular Disease Cancer
Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types .

HY-P5497

C34 peptide	HIV	Others
C34 peptide is a biological active peptide. (This C34 peptide, also known as HR2, belongs to the helical region of gp41 of HIV, C-terminal heptad repeat 2 (HR2) defined as C helix or C peptide. It is known that HIV-1 enters cells by membrane fusion, C34 gp41 peptide is a potent inhibitors of HIV-1 fusion.)

HY-P5472

Tumour-associated MUC1 epitope	Peptides	Others
Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)

Species:	Human (3) Mouse (1)
Tag:	His (4) Strep (1)
Source:	HEK293 (3) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70878A

	EDIL3 Protein, Human (HEK293, His) EGF-Like repeats and Discoidin I-Like Domains 3; EDIL3	Human	HEK293
	EDIL3 Protein enhances endothelial cell adhesion by interacting with the alpha-v/beta-3 integrin receptor, while also inhibiting the formation of vascular-like structures. Its role suggests involvement in the regulation of vascular morphogenesis during embryonic development. EDIL3 Protein, Human (HEK293, His) is the recombinant human-derived EDIL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EDIL3 Protein, Human (HEK293, His) is 457 a.a., with molecular weight of ~56 kDa.

HY-P70878

	EDIL3 Protein, Human (HEK293, His, solution) EGF-Like repeats and Discoidin I-Like Domains 3; EDIL3	Human	HEK293
	EDIL3 Protein enhances endothelial cell adhesion by interacting with the alpha-v/beta-3 integrin receptor, while also inhibiting the formation of vascular-like structures. Its role suggests involvement in the regulation of vascular morphogenesis during embryonic development. EDIL3 Protein, Human (HEK293, His, solution) is the recombinant human-derived EDIL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EDIL3 Protein, Human (HEK293, His, solution) is 457 a.a., with molecular weight of ~56 kDa.

HY-P70398

	LRIG1 Protein, Mouse (HEK293, His) rMuLeucine-rich repeats and immunoglobulin-like domains protein 1/LRIG1, His; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; Lrig1	Mouse	HEK293
	The LRIG1 protein acts as a negative feedback regulator of receptor tyrosine kinase signaling by promoting receptor ubiquitination and accelerating intracellular degradation.Its extracellular LRR and Ig-like domains can interact with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.LRIG1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LRIG1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P701530

	ANKFY1 Protein, Human (Sf9, His, Strep) ANKFY1; Rabankyrin-5; Rank-5; Ankyrin repeat and FYVE domain-containing protein 1; Ankyrin repeats hooked to a zinc finger motif	Human	Sf9 insect cells
	ANKFY1 is a proposed Rab5 effector that critically participates in endosomal dynamics by binding to PI(3)P, promoting homotypic early endosomal fusion and participating in heterotypic fusion. It plays a crucial role in macropinocytosis, is dependent on Rab5-GTP, and is essential for the correct localization of activated tyrosine kinase receptors such as PDGFRB. ANKFY1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ANKFY1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ANKFY1 Protein, Human (Sf9, His, Strep) is 1168 a.a., .

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81434

	BANK1 Antibody (YA1179) BANK1; B-cell scaffold protein with ankyrin repeats	IHC-P	Human
	BANK1 Antibody (YA1179) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1179), targeting BANK1. BANK1 Antibody (YA1179) can be used for IHC-P experiment in human background.

HY-P82565

	SorLA Antibody (YA2310) SORL1; C11orf32; Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repe	WB, IHC-P	Human, Mouse, Rat
	SorLA Antibody (YA2310) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2310), targeting SorLA, with a predicted molecular weight of 248 kDa (observed band size: 270 kDa). SorLA Antibody (YA2310) can be used for WB, IHC-P experiment in human, mouse, rat background.