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Results for "

rhinitis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (2) Adrenergic Receptor (1) Aldehyde Dehydrogenase (ALDH) (1) Angiotensin Receptor (1) Antibiotic (6) Apoptosis (3) Autophagy (5) Bacterial (8) Calcium Channel (4) Dopamine Receptor (1) Drug Metabolite (5) Endogenous Metabolite (7) Enterovirus (2) Glucocorticoid Receptor (12) Histamine Receptor (74) Isotope-Labeled Compounds (15) Leukotriene Receptor (1) Lipoxygenase (1) mAChR (5) Phosphodiesterase (PDE) (1) Potassium Channel (4) Prostaglandin Receptor (1) SARS-CoV (6) Sigma Receptor (1) Sodium Channel (4) STAT (3) Syk (1) TNF Receptor (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (3) Endocrinology (50) Infection (16) Inflammation/Immunology (107) Metabolic Disease (7) Neurological Disease (11)

By Targets:

ADC Cytotoxin (2)

Adrenergic Receptor (1)

Aldehyde Dehydrogenase (ALDH) (1)

Angiotensin Receptor (1)

Antibiotic (6)

Apoptosis (3)

Autophagy (5)

Bacterial (8)

Calcium Channel (4)

Dopamine Receptor (1)

Drug Metabolite (5)

Endogenous Metabolite (7)

Enterovirus (2)

Glucocorticoid Receptor (12)

Histamine Receptor (74)

Isotope-Labeled Compounds (15)

Leukotriene Receptor (1)

Lipoxygenase (1)

mAChR (5)

Phosphodiesterase (PDE) (1)

Potassium Channel (4)

Prostaglandin Receptor (1)

SARS-CoV (6)

Sigma Receptor (1)

Sodium Channel (4)

STAT (3)

Syk (1)

TNF Receptor (1)

Toll-like Receptor (TLR) (1)

By Research Areas:

Cancer (12)

Cardiovascular Disease (3)

Endocrinology (50)

Infection (16)

Inflammation/Immunology (107)

Metabolic Disease (7)

Neurological Disease (11)

120

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0462

Azelastine hydrochloride 1 Publications Verification	Histamine Receptor SARS-CoV	Infection Metabolic Disease Inflammation/Immunology Endocrinology
Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H₁) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 .

HY-B0674

Ebastine 1 Publications Verification LAS-W 090; RP64305	Histamine Receptor	Inflammation/Immunology Endocrinology
Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .

HY-B1062

Dexchlorpheniramine maleate S-(+)-Chlorpheniramine maleate salt	Histamine Receptor	Inflammation/Immunology Endocrinology
Dexchlorpheniramine maleate is an orally taken anti-histamine that has anti-inflammatory, anti-irritant, anti-allergic, and skin barrier effects. Dexchlorpheniramine maleate inhibits myocardial contraction in rats. Dexchlorpheniramine maleate can be used in studies of allergic rhinitis .

HY-111269

AZD8848 1 Publications Verification	Toll-like Receptor (TLR)	Inflammation/Immunology
AZD8848 is a selective toll-like receptor 7 (TLR7) anteagent agonist which is developed for the research of asthma and allergic rhinitis .

HY-108030

Bencycloquidium bromide	mAChR	Neurological Disease Inflammation/Immunology Cancer
Bencycloquidium bromide, a muscarinic M(3) receptor antagonist, is an anticholinergic compound that acts as an anticholinergic bronchodilator. Bencycloquidium bromide can be used in the study for rhinitis .

HY-106368

Dexamethasone cipecilate NS-126	Glucocorticoid Receptor	Inflammation/Immunology
Dexamethasone cipecilate (NS-126) is a corticosteroid whose local efficacy and durability have been enhanced by the introduction of a lipophilic functional group. Dexamethasone cipecilate can be used as a nasal spray and is applicable in rhinitis research .

HY-B0462A

Azelastine	Histamine Receptor SARS-CoV	Infection Metabolic Disease Inflammation/Immunology Endocrinology
Azelastine, an antihistamine, is a potent and selective histamine 1 (H₁) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 .

HY-B0462B

(S)-Azelastine hydrochloride (+)-Azelastine hydrochloride	Histamine Receptor SARS-CoV	Infection Metabolic Disease Inflammation/Immunology Endocrinology
(S)-Azelastine hydrochloride, an antihistamine, is a potent and selective histamine 1 (H₁) antagonist. (S)-Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 .

HY-N9977

Dihydrocatalpol	Others	Inflammation/Immunology
Dihydrocatalpol can be isolated from Rehmannia glutinosa. Dihydrocatalpol can be used for research on Asthma, chronic obstructive pneumonia, allergic rhinitis .

HY-B1808A

Triprolidine hydrochloride	Histamine Receptor	Neurological Disease Inflammation/Immunology
Triprolidine hydrochloride is an orally active histamine H1 antagonist. Triprolidine hydrochloride has the function of spinal cord motor and sensory block. Triprolidine hydrochloride can be used for the research of allergic rhinitis .

HY-106567

Fluocortin butyl ester	Glucocorticoid Receptor	Inflammation/Immunology
Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when it is used topically. Fluocortin butyl ester appears to be an effective well-tolerated topical steroid useful in the research of perennial rhinitis .

HY-B1808

Triprolidine	Histamine Receptor	Infection
Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis .

HY-17428

Tripelennamine hydrochloride	Histamine Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-17428A

Tripelennamine	Histamine Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Tripelennamine, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine lessens the allergic response of the organism caused by histamine. Tripelennamine can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-B1301

Triprolidine hydrochloride monohydrate	Histamine Receptor	Neurological Disease Inflammation/Immunology
Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats .

HY-119832

Setastine EGIS-2062 free acid; EGYT-2062 free acid	Histamine Receptor	Inflammation/Immunology
Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research ^[1]<.

HY-B0801A

Fexofenadine hydrochloride 4 Publications Verification MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride	Histamine Receptor	Inflammation/Immunology Cancer
Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H₁ receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .

HY-B0801

Fexofenadine 4 Publications Verification MDL-16455; Terfenadine carboxylate	Histamine Receptor	Inflammation/Immunology Cancer
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .

HY-13511A

Rupatadine Fumarate 2 Publications Verification UR-12592 Fumarate	Histamine Receptor Autophagy	Inflammation/Immunology
Rupatadine (UR-12592) Fumarate is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K_is of 0.55 μM and 0.1 μM, respectively. Rupatadine Fumarate can be used for the research of allergic rhinitis and urticaria .

HY-13511

Rupatadine UR-12592	Histamine Receptor Autophagy	Inflammation/Immunology
Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K_is of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria .

HY-17428B

Tripelennamine citrate	Histamine Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Tripelennamine citrate, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine citrate lessens the allergic response of the organism caused by histamine. Tripelennamine citrate can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-B1619

Cromolyn 3 Publications Verification Cromoglicic acid	Others	Inflammation/Immunology
Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis .

HY-B0462R

Azelastine (hydrochloride) (Standard)	Histamine Receptor SARS-CoV	Infection Metabolic Disease Inflammation/Immunology Endocrinology
Azelastine (hydrochloride) (Standard) is the analytical standard of Azelastine (hydrochloride). This product is intended for research and analytical applications. Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H₁) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 .

HY-B0674R

Ebastine (Standard)	Histamine Receptor	Inflammation/Immunology Endocrinology
Ebastine (Standard) is the analytical standard of Ebastine. This product is intended for research and analytical applications. Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .

HY-B0674S1

Ebastine-d6 LAS-W 090-d₆; RP64305-d₆	Histamine Receptor Isotope-Labeled Compounds	Inflammation/Immunology Endocrinology
Ebastine-d₆ is deuterated labeled Ebastine (HY-B0674). Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .

HY-123812

PF-03654764	Histamine Receptor	Neurological Disease Inflammation/Immunology
PF-03654764 is an orally active, selective histamine H₃ receptor antagonist with K_i values of 1.2 nM and 7.9 nM for human H₃ and rat H₃ in whole cell assay, respectively. The combination of PF-03654764 and Fexofenadine (HY-B0801A) has the potential for allergic rhinitis research .

HY-13511R

Rupatadine (Standard)	Histamine Receptor Autophagy	Inflammation/Immunology
Rupatadine (Standard) is the analytical standard of Rupatadine. This product is intended for research and analytical applications. Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria .

HY-B1301R

Triprolidine (hydrochloride monohydrate) (Standard)	Histamine Receptor	Neurological Disease Inflammation/Immunology
Triprolidine (hydrochloride monohydrate) (Standard) is the analytical standard of Triprolidine (hydrochloride monohydrate). This product is intended for research and analytical applications. Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats .

HY-13511S

Rupatadine-d6 D-tartrate UR-12592-d6	Histamine Receptor Autophagy Isotope-Labeled Compounds	Inflammation/Immunology
Rupatadine-d₆ (D-tartrate) is deuterated labeled Rupatadine (HY-13511). Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K_is of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria .

HY-B0801S4

Fexofenadine-d3-1 MDL-16455-d₃-1; Terfenadine carboxylate-d₃-1	Histamine Receptor Isotope-Labeled Compounds	Inflammation/Immunology
Fexofenadine-d₃-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .

HY-108411

Emedastine 1 Publications Verification	Histamine Receptor	Inflammation/Immunology
Emedastine is an orally active, selective and high affinity histamine H₁ receptor antagonist with a K_i value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis .

HY-B2178

Emedastine difumarate	Histamine Receptor	Inflammation/Immunology
Emedastine difumarate is an orally active, selective and high affinity histamine H₁ receptor antagonist with a K_i value of 1.3 nM. Emedastine difumarate is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis .

HY-15234

Fluticasone furoate	Glucocorticoid Receptor	Inflammation/Immunology
Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a K_d of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .

HY-107784

Ectoine	Bacterial	Inflammation/Immunology
Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-106996

AWD 12-281 GW 842470	Phosphodiesterase (PDE)	Inflammation/Immunology
AWD 12-281 is an orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 9.7 nM). AWD 12-281 is used in the study of allergic dermatitis, asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis .

HY-108411R

Emedastine (Standard)	Histamine Receptor	Inflammation/Immunology
Emedastine (Standard) is the analytical standard of Emedastine. This product is intended for research and analytical applications. Emedastine is an orally active, selective and high affinity histamine H₁ receptor antagonist with a K_i value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis .

HY-B0970

Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor	Neurological Disease Endocrinology
Diphenylpyraline hydrochloride is a potent histamine H₁?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.

HY-107431

Diphenylpyraline	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline is a potent histamine H₁ receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

HY-B2178R

Emedastine (difumarate) (Standard)	Histamine Receptor	Inflammation/Immunology
Emedastine (difumarate) (Standard) is the analytical standard of Emedastine (difumarate). This product is intended for research and analytical applications. Emedastine difumarate is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine difumarate is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis .

HY-W778340

16α-Hydroxy-11-keto prednisolone	Drug Metabolite Glucocorticoid Receptor	Inflammation/Immunology Cancer
16α-Hydroxy-11-keto prednisolone (compound M-X) is a metabolite of Budesonide (HY-13580). Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide is a widely used for study of asthma, rhinitis, and inflammatory bowel disease .

HY-16635

Setipiprant ACT-129968; KYTH-105	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
Setipiprant (ACT-129968) is an orally active and selective CRTH2 antagonist. Setipiprant interacts with hCRTH2 receptor with an IC₅₀ value of 6 nM. Setipiprant inhibits prostanoid receptors hDP₁ and hEP₂ with IC₅₀ values of 1290 and 2600 nM, respectively. Setipiprant can be used for the research of asthma and rhinitis .

HY-107784R

Ectoine (Standard)	Bacterial	Inflammation/Immunology
Ectoine (Standard) is the analytical standard of Ectoine. This product is intended for research and analytical applications. Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-B0164

Mizolastine	Histamine Receptor	Inflammation/Immunology
Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .

HY-B0164A

Mizolastine dihydrochloride	Histamine Receptor	Inflammation/Immunology
Mizolastine dihydrochloride is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine dihydrochloride effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine dihydrochloride can be used in studies of allergic rhinitis and chronic idiopathic urticarial .

HY-15234R

Fluticasone furoate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Fluticasone furoate (Standard) is the analytical standard of Fluticasone furoate. This product is intended for research and analytical applications. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a K_d of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .

HY-B0480

Brompheniramine maleate 1 Publications Verification (±)-Brompheniramine maleate	Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel	Neurological Disease Inflammation/Immunology Endocrinology
Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a K_d of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, and sodium channels with IC₅₀s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research .

HY-B0480A

Brompheniramine (±)-Brompheniramine	Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel	Neurological Disease Inflammation/Immunology Endocrinology
Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a K_d of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with IC₅₀s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research .

HY-147336

Desmethylazelastine	Drug Metabolite	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Desmethylazelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. Azelastine is an orally active, selective and high-affinity histamine H1-receptor antagonist. Azelastine can be used in studies of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 .

HY-16420

R112	Syk	Inflammation/Immunology
R112 is a fast and reversible inhibitor of spleen tyrosine kinase (Syk) kinase. R112 inhibits Syk kinase activity with an IC₅₀ value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcεRI signaling pathway. R112 can be used for the research of allergic rhinitis .

HY-107431R

Diphenylpyraline (Standard)	Histamine Receptor	Inflammation/Immunology
Diphenylpyraline (Standard) is the analytical standard of Diphenylpyraline. This product is intended for research and analytical applications. Diphenylpyraline is a potent histamine H1?receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17428

Tripelennamine hydrochloride	Structural Classification Alkaloids Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite
Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-107784

Ectoine	Structural Classification Microorganisms Classification of Application Fields Source classification Amino acids Inflammation/Immunology Disease Research Fields	Bacterial
Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-113434

5(S)-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma .

HY-N9977

Dihydrocatalpol	Structural Classification Natural Products Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey	Others
Dihydrocatalpol can be isolated from Rehmannia glutinosa. Dihydrocatalpol can be used for research on Asthma, chronic obstructive pneumonia, allergic rhinitis .

HY-17428A

Tripelennamine	Structural Classification Alkaloids Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Histamine Receptor Endogenous Metabolite
Tripelennamine, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine lessens the allergic response of the organism caused by histamine. Tripelennamine can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-17428B

Tripelennamine citrate	Structural Classification Alkaloids Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Histamine Receptor Endogenous Metabolite
Tripelennamine citrate, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine citrate lessens the allergic response of the organism caused by histamine. Tripelennamine citrate can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-107784R

Ectoine (Standard)	Structural Classification Microorganisms Source classification Amino acids	Bacterial
Ectoine (Standard) is the analytical standard of Ectoine. This product is intended for research and analytical applications. Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-N7293

Bakkenolide D	Structural Classification Natural Products Valeriana jatamansi Jones Source classification Plants Valerianaceae	Others
Bakkenolide D is the main component of bakkenolide in Petasites tricholobus. Bakkenolide has anti-allergic effects and can be used in the study of allergic rhinitis .

HY-129482

Detoxin D1	Structural Classification Natural Products Microorganisms Source classification	Others
Detoxin D1 is a compound with antihistamine activity and a new type of H1 antagonist. In the suppression of seasonal allergic rhinitis, a daily dose of 10-30 mg has an equivalent and highly effective inhibitory effect compared with placebo and has good safety.

HY-17428R

Tripelennamine (hydrochloride) (Standard)	Structural Classification Alkaloids Source classification Pyridine Alkaloids Endogenous metabolite	Histamine Receptor Endogenous Metabolite
Tripelennamine (hydrochloride) (Standard) is the analytical standard of Tripelennamine (hydrochloride). This product is intended for research and analytical applications. Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions .

HY-N12708

23-O-β-D-Glucopyranosyl-20-isoveratramine	Structural Classification Alkaloids Piperidine Alkaloids Source classification Plants Melanthiaceae Veratrum oxysepalum Turcz.	Others
23-O-β-D-Glucopyranosyl-20-isoveratramine is a potential anti-allergic agent extracted from nettles. A variety of COX-1, COX-2, 5-lipoxygenase and trypsin-like inhibitors and H1 antagonists are found in nettle extract, which can inhibit seasonal allergies, allergic rhinitis and other inflammatory diseases. and preventive effects .

HY-B0539

Desloratadine Maximum Cited Publications 10 Publications Verification Sch34117	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology	Histamine Receptor TNF Receptor Leukotriene Receptor
Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (K_i=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria .

HY-N2597

Prunetin	Structural Classification Classification of Application Fields Source classification Trifolium pratense Linn. Plants Flavonoids Leguminosae Phenols Polyphenols Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Isoflavones	Aldehyde Dehydrogenase (ALDH)
Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor .

HY-B0154R

Fluticasone (propionate) (Standard)	Structural Classification Source classification Steroids	Glucocorticoid Receptor Enterovirus Endogenous Metabolite ADC Cytotoxin
Fluticasone (propionate) (Standard) is the analytical standard of Fluticasone (propionate). This product is intended for research and analytical applications. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-17042

Cetirizine 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Histamine Receptor
Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .

HY-17042R

Cetirizine (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Histamine Receptor
Cetirizine (Standard) is the analytical standard of Cetirizine. This product is intended for research and analytical applications. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .

HY-B0519

Tylosin tartrate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519A

Tylosin 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519B

Tylosin phosphate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519AR

Tylosin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research	Bacterial Antibiotic
Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519BR

Tylosin (phosphate) (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Antibacterial Disease Research	Bacterial Antibiotic
Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519R

Tylosin (tartrate) (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research	Bacterial Antibiotic
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

Cat. No.	Product Name	Chemical Structure

HY-B0674S1

Ebastine-d6
Ebastine-d₆ is deuterated labeled Ebastine (HY-B0674). Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .

HY-13511S

Rupatadine-d6 D-tartrate
Rupatadine-d₆ (D-tartrate) is deuterated labeled Rupatadine (HY-13511). Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K_is of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria .

HY-B0801S4

Fexofenadine-d3-1
Fexofenadine-d₃-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .

HY-B1121S

Flunisolide-d6
Flunisolide-d₆ is the deuterium labeled Flunisolide. Flunisolide is a corticosteroid often used to treat allergic rhinitis.The principal mechanism of action of Flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action.

HY-B0801AS

Fexofenadine-d10 hydrochloride
Fexofenadine-d₁₀ (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years)[1].

HY-B1619S

Cromoglicic acid-d5
Cromoglicic acid-d₅ is the deuterium labeled Cromolyn[1]. Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis[2].

HY-B0674S

Ebastine-d5
Ebastine-d₅ is the deuterium labeled Ebastine. Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1][2].

HY-B0801S2

Fexofenadine-d3
Fexofenadine-d₃ is the deuterium labeled Fexofenadine[1]. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research[2][3][4].

HY-100657S

Meta-Fexofenadine-d6
Meta-Fexofenadine-d₆ is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].

HY-B0462AS

Azelastine-13C,d3
Azelastine- ¹³C,d₃ is deuterium labeled Azelastine. Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4].

HY-14447S1

Bilastine-d4
Bilastine-d₄ is deuterium labeled Bilastine. Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system .

HY-15234S

Fluticasone furoate-d3
Fluticasone furoate-d₃ is deuterium labeled Fluticasone furoate. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment[1][2].

HY-108411S

Emedastine-13C,d3 fumarate
Emedastine- ¹³C,d₃ (fumarate) is the ¹³C- and deuterium labeled Emedastine. Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis[1][2][3].

HY-A0015S

Bepotastine-d6(besylate)
Bepotastine-d₆(besylate) is deuterium labeled Bepotastine (besilate). Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .

HY-B0814S

Levocetirizine-d4 dihydrochloride

Levocetirizine-d₄ (dihydrochloride) is the deuterium labeled Levocetirizine. Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1].

HY-B0462S

Azelastine-13C,d3 hydrochloride
Azelastine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Azelastine hydrochloride. Azelastine- ¹³C,d₃ (hydrochloride), an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine- ¹³C,d₃ (hydrochloride) can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4].

HY-B0814S1

Levocetirizine-d4

Levocetirizine-d₄ ((R)-Cetirizine-d₄) is the deuterium-labeled Levocetirizine (HY-B0814) . Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria .

HY-17042AS1

Cetirizine-d8 dihydrochloride
Cetirizine-d₈ (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

HY-17042S

Cetirizine-d4
Cetirizine-d₄ is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

HY-17042S1

Cetirizine-d8
Cetirizine-d₈ is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

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