1. Anti-infection
  2. Bacterial
  3. Ectoine

Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis.

For research use only. We do not sell to patients.

Ectoine Chemical Structure

Ectoine Chemical Structure

CAS No. : 96702-03-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
USD 61 In-stock
Solution
10 mM * 1 mL in Water USD 61 In-stock
Solid
100 mg USD 55 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ectoine:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis[1][2].

IC50 & Target

Bacterial[1]

In Vitro

Ectoine (0-5% (w/v); 0-24 h; human erythrocytes) protects the cells from damage caused by SDS treatment[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

142.16

Formula

C6H10N2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1NC(C)=NCC1)O

Structure Classification
Initial Source

Ethtothiorhodospiru halochloris、Ehalonas elongata

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1758.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.0343 mL 35.1716 mL 70.3433 mL
5 mM 1.4069 mL 7.0343 mL 14.0687 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (703.43 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.0343 mL 35.1716 mL 70.3433 mL 175.8582 mL
5 mM 1.4069 mL 7.0343 mL 14.0687 mL 35.1716 mL
10 mM 0.7034 mL 3.5172 mL 7.0343 mL 17.5858 mL
15 mM 0.4690 mL 2.3448 mL 4.6896 mL 11.7239 mL
20 mM 0.3517 mL 1.7586 mL 3.5172 mL 8.7929 mL
25 mM 0.2814 mL 1.4069 mL 2.8137 mL 7.0343 mL
30 mM 0.2345 mL 1.1724 mL 2.3448 mL 5.8619 mL
40 mM 0.1759 mL 0.8793 mL 1.7586 mL 4.3965 mL
50 mM 0.1407 mL 0.7034 mL 1.4069 mL 3.5172 mL
60 mM 0.1172 mL 0.5862 mL 1.1724 mL 2.9310 mL
80 mM 0.0879 mL 0.4396 mL 0.8793 mL 2.1982 mL
100 mM 0.0703 mL 0.3517 mL 0.7034 mL 1.7586 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ectoine
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HY-107784
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