2. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Isotope-Labeled Compounds Histamine Receptor
  4. Cetirizine-d8 dihydrochloride

Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

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Cetirizine-d<sub>8</sub> dihydrochloride Chemical Structure

Cetirizine-d8 dihydrochloride Chemical Structure

CAS No. : 2070015-04-0

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Other Forms of Cetirizine-d8 dihydrochloride:

Cetirizine-d8 dihydrochloride Related Antibodies

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Description

Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

IC50 & Target

H1 Receptor

 

Molecular Weight

469.86

Formula

C21H19D8Cl3N2O3
CAS No.
Unlabeled CAS

83881-52-1
SMILES

ClC1=CC=C(C(N2C([2H])([2H])C([2H])([2H])N(CCOCC(O)=O)C([2H])([2H])C2([2H])[2H])C3=CC=CC=C3)C=C1.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cetirizine-d8 dihydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cetirizine-d82070015-04-0Isotope-Labeled CompoundsHistamine ReceptorhistamineSARARIL-1βGM-CSFIL-8SeasonalallergicrhinitisInhibitorinhibitorinhibit

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