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Results for "

schizophrenic

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106100A
    Roxindole hydrochloride

    EMD 38362

    		 Dopamine Receptor Serotonin Transporter Neurological Disease
    Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities .
    Roxindole hydrochloride
  • HY-B0731A
    Perospirone

    SM-9018 free base

    		 5-HT Receptor Dopamine Receptor Neurological Disease
    Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research .
    Perospirone
  • HY-B0731
    Perospirone hydrochloride

    SM-9018

    		 5-HT Receptor Dopamine Receptor Neurological Disease
    Perospirone hydrochloride (SM-9018) is an orally active antagonist of 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM). Perospirone hydrochloride is also a partial agonist of 5-HT1A receptor (Ki of 2.9 nM). Perospirone hydrochloride is an atypical antipsychotic agent and has the potential for schizophrenic disease research .
    Perospirone hydrochloride
  • HY-A0211
    Carphenazine

    		Others Neurological Disease
    Carphenazine is a phenothiazine antipsychotic agent. Carphenazine can be used for researching chronic schizophrenic psychoses .
    Carphenazine
  • HY-122128
    Lilly 51641

    LY-51641

    		 Monoamine Oxidase Neurological Disease
    Lilly 51641 (LY-51641) is a selective and orally active Type A monoamine oxidase inhibitor. Lilly 51641 has the potential for the research of depressed and schizophrenic .
    Lilly 51641
  • HY-132494S
    Perazine-d8

    		Isotope-Labeled Compounds Others Others
    Perazine-d8 is a deuterated form of Perazine. Perazine is a potent and orally active antidepressant agent. Perazine has the potential for the research of acute schizophrenics[1][2].
    Perazine-d8
  • HY-121813
    Rimcazole

    BW 234U

    		 Others Neurological Disease
    Rimcazole (BW 234U) is a potent antipsychotic agent. Rimcazole also is a competitive antagonist of sigma sites. Rimcazole can be used for the research of acute schizophrenic diseases .
    Rimcazole
  • HY-106100
    Roxindole

    EMD 49980

    		 Dopamine Receptor Serotonin Transporter Neurological Disease
    Roxindole (EMD 49980), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor. Antipsychotic and antidepressant activities .
    Roxindole
  • HY-B0731R
    Perospirone hydrochloride (Standard)

    		5-HT Receptor Dopamine Receptor Neurological Disease
    Perospirone (hydrochloride) (Standard) is the analytical standard of Perospirone (hydrochloride). This product is intended for research and analytical applications. Perospirone hydrochloride (SM-9018) is an orally active antagonist of 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM). Perospirone hydrochloride is also a partial agonist of 5-HT1A receptor (Ki of 2.9 nM). Perospirone hydrochloride is an atypical antipsychotic agent and has the potential for schizophrenic disease research .
    Perospirone hydrochloride (Standard)
  • HY-116746
    Clopimozide

    		Calcium Channel Neurological Disease
    Clopimozide is an orally active antischizophrenic agent that inhibits [ 3H]nitrendipine binding with IC50 value of 17 nM. Clopimozide is a calcium channel antagonist. Clopimozide can be used for the research of negative and positive schizophrenic symptoms .
    Clopimozide
  • HY-157958
    α7 nAChR Modulator-3

    		nAChR Neurological Disease
    α7 nAChR modulator-3 (Compound 6p) is a α7 nAChR positive allosteric Modulator with a IC50 value of 1.3 μM. α7 nAChR Modulator-3 can be used to inhibit auditory gating defects in a mouse schizophrenic model .
    α7 nAChR Modulator-3

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