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two carboxylic acid

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

1

Fluorescent Dye

4

Biochemical Assay Reagents

1

Peptides

1

Click Chemistry

4

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W800793
    16:0 Succinyl PE

    1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)

    		 Liposome Cancer
    16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
    16:0 Succinyl PE
  • HY-W073501A
    Glutaconic acid

    2-Pentenedioic acid

    		 Biochemical Assay Reagents Others
    Glutaconic acid is an organic compound with two carboxylic acid groups .
    Glutaconic acid
  • HY-W800792
    18:1 Succinyl PE

    1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)

    		 Liposome Cancer
    18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.
    18:1 Succinyl PE
  • HY-W073382
    4-(3-Tosyl-2-(tosylmethyl)propanoyl)benzoic acid

    Bis–sulfone acid

    		 Biochemical Assay Reagents Others
    4-(3-Tosyl-2-(tosylmethyl)propanoyl)benzoic acid (Bis-sulfone Acid) is a strong covalent linker featuring a free carboxylic acid and two tosyl groups. Each tosyl group can be displaced by thiol or amine nucleophiles via a Michael addition, and the inclusion of two on this molecule allow this reaction to proceed twice. This may be used to “staple” two reduced cysteine residues on a given protein to reform disulfide bridges. The carboxylic acid is free to react to form amides or esters.
    4-(3-Tosyl-2-(tosylmethyl)propanoyl)benzoic acid
  • HY-W671472
    10-Oxononadecanedioic acid

    		Biochemical Assay Reagents Others
    10-Oxononadecanedioic acid is a long alkane linker with two terminal carboxylic acid groups. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
    10-Oxononadecanedioic acid
  • HY-W800794
    16:0 Glutaryl PE

    DPPE-NG; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)

    		 Liposome Cancer
    16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
    16:0 Glutaryl PE
  • HY-W800795
    18:1 Dodecanyl PE

    DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)

    		 Liposome Cancer
    18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
    18:1 Dodecanyl PE
  • HY-W800844
    NH-bis(PEG8-OH)

    		Biochemical Assay Reagents Others
    NH-bis(PEG8-OH) is a homobifunctional reagent containing two alcohols joined together by a secondary amine. The alcohols can be used in a variety of ways such as in forming esters with carboxylic acids, while the secondary amine can be used as a nucleophile in linking with ketones, aldehydes, and carboxylic acids. The PEG spacers make this molecule water-soluble, potentially altering its DMPK properties.
    NH-bis(PEG8-OH)
  • HY-W591402
    3,4-Dibromo-Mal-PEG4-Acid

    		ADC Linker Cancer
    3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
    3,4-Dibromo-Mal-PEG4-Acid
  • HY-W190915
    4,7,10,13,16-Pentaoxanonadecane-1,19-diamine

    		Biochemical Assay Reagents Others
    4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    4,7,10,13,16-Pentaoxanonadecane-1,19-diamine
  • HY-W591379
    Amino-PEG19-amine

    		Biochemical Assay Reagents Others
    Amino-PEG19-amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
    Amino-PEG19-amine
  • HY-W800708
    N-(TCO)-N-bis(PEG4-acid)

    		Biochemical Assay Reagents Others
    N-(TCO)-N-bis(PEG4-acid) is a branched click chemistry reagent with a terminal TCO group and two terminal carboxylic acids. This reagent can react with tetrazine-containing molecule to form a stable covalent bond . The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acids can react with primary amino groups in the presence of activators (e.g. EDC, HATU ).
    N-(TCO)-N-bis(PEG4-acid)
  • HY-W190905
    N4,N9-di-Boc-spermine

    		Biochemical Assay Reagents Others
    N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
    N4,N9-di-Boc-spermine
  • HY-130695
    N-(Amino-PEG5)-N-bis(PEG4-acid)

    		PROTAC Linkers Cancer
    N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used in the synthesis of PROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids .
    N-(Amino-PEG5)-N-bis(PEG4-acid)
  • HY-W092344
    1,5-Bis-boc-1,5,9-triazanonane

    		Biochemical Assay Reagents Others
    1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    1,5-Bis-boc-1,5,9-triazanonane
  • HY-42213
    N1,N4-Bis-Boc-spermidine

    		Biochemical Assay Reagents Others
    N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N4-Bis-Boc-spermidine
  • HY-42222
    N1,N5-Bis-boc-spermidine

    		Biochemical Assay Reagents Others
    N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N5-Bis-boc-spermidine
  • HY-WAA0302
    1,4-Bis-boc-1,4,7-triazaheptane

    		Biochemical Assay Reagents Others
    1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    1,4-Bis-boc-1,4,7-triazaheptane
  • HY-W012885
    (S)-Methyl 3-hydroxybutanoate

    		Biochemical Assay Reagents Others
    (S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.
    (S)-Methyl 3-hydroxybutanoate
  • HY-D2751
    BP Fluor 488 cadaverine

    		Fluorescent Dye Others
    BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. BP Fluor 488 dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
    BP Fluor 488 cadaverine
  • HY-W127409
    1,2-Dimyristoyl-rac-glycerol

    		Biochemical Assay Reagents Others
    1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.
    1,2-Dimyristoyl-rac-glycerol
  • HY-136410
    4-hydroxy Nonenal Mercapturic Acid

    		Endogenous Metabolite Metabolic Disease
    4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
    4-hydroxy Nonenal Mercapturic Acid
  • HY-23212A
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride

    		Amino Acid Derivatives Cancer
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride is a non-protein amino acid, sulfamic acid.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride contains one amino group and two terminal carboxylic acids.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride has a variety of physiological functions, including maintaining the stability of cell membranes, regulating cholesterol metabolism, supporting the normal function of the nervous system, participating in collagen synthesis, and anti-oxidation .
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride
  • HY-W061674
    trans-2-Pentenoic acid

    (E)-Pent-2-enoic acid

    		 Biochemical Assay Reagents Others
    (2E)-Pent-2-enoic acid is an unsaturated carboxylic acid, it is also known as 2-pentenoic acid or crotonic acid, the "2E" designation indicates that the molecule has a trans double bond configuration, where the double bond The two carbon atoms on both sides are located on opposite sides, (2E)-Pent-2-enoic acid has a pungent odor, is miscible with water and most organic solvents, it is commonly used in organic synthesis as a variety of chemical reactions, including esterification, oxidation, and reduction, and in addition, its potential use as a flavoring agent in the food industry was investigated.
    trans-2-Pentenoic acid
  • HY-W010361
    Tetramethylammonium acetate

    		Biochemical Assay Reagents Others
    Tetramethylammonium acetate is an organic compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. Additionally, Tetramethylammonium acetate has been used to prepare a variety of organic compounds, including esters, amides, and carboxylic acids. Due to its unique physicochemical properties, it has also been investigated for its potential use in developing new materials such as ionic liquids and liquid crystals. "x" in the formula represents the number of water molecules in the crystal structure, which can vary depending on the preparation method.
    Tetramethylammonium acetate
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide
  • HY-151833
    Methyltetrazine-amido-N-bis(PEG4-acid)

    		ADC Linker Others
    Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Methyltetrazine-amido-N-bis(PEG4-acid)

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