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Results for "

upper

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenosine Receptor (1) Antibiotic (4) Bacterial (5) Beta-secretase (2) Biochemical Assay Reagents (1) Calcium Channel (3) Cholinesterase (ChE) (2) Cytochrome P450 (1) Dopamine Receptor (1) Endogenous Metabolite (8) Histamine Receptor (2) Influenza Virus (3) Isotope-Labeled Compounds (1) Na+/K+ ATPase (1) NO Synthase (1) Potassium Channel (1) Proton Pump (3) Ser/Thr Protease (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (3) Endocrinology (3) Infection (14) Inflammation/Immunology (7) Metabolic Disease (5) Neurological Disease (6)

By Targets:

5-HT Receptor (1)

Adenosine Receptor (1)

Antibiotic (4)

Bacterial (5)

Beta-secretase (2)

Biochemical Assay Reagents (1)

Calcium Channel (3)

Cholinesterase (ChE) (2)

Cytochrome P450 (1)

Dopamine Receptor (1)

Endogenous Metabolite (8)

Histamine Receptor (2)

Influenza Virus (3)

Isotope-Labeled Compounds (1)

Na+/K+ ATPase (1)

NO Synthase (1)

Potassium Channel (1)

Proton Pump (3)

Ser/Thr Protease (1)

Toll-like Receptor (TLR) (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (3)

Endocrinology (3)

Infection (14)

Inflammation/Immunology (7)

Metabolic Disease (5)

Neurological Disease (6)

Inhibitors & Agonists

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110296

EC19	Endogenous Metabolite	Metabolic Disease
EC19 is an analogue of 13-cis retinoic acid (HY-15127). EC19 shows embryo toxicity. EC19 causes mild effects on upper beak outgrowth .

HY-A0161A

Chlophedianol hydrochloride Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride	Others	Infection
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-W709856

Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide	Influenza Virus	Infection
Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations, which might be used for research of common cold and various upper respiratory infections .

HY-W011518

2′-Deoxy-2′-fluoroguanosine	Influenza Virus	Infection
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC₉₀ of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation .

HY-113008

Urocanic acid 1 Publications Verification	Endogenous Metabolite	Cancer
Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).

HY-B2233

Phosphorylcholine chloride 5 Publications Verification Phosphocholine chloride	Endogenous Metabolite	Cardiovascular Disease
Phosphorylcholine chloride (Phosphocholine chloride) is an antigenic cell-surface component found on many commensal and pathogenic bacteria that reside in the upper airway.

HY-A0111

Cefetamet Ro 15-8074; Deacetoxycefotaxime	Antibiotic Bacterial	Infection
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-A0161

Chlophedianol Clofedanol; Calmotusin; NSC 113595	Others	Infection
Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-A0111A

Cefetamet sodium Ro15-8074/001; Deacetoxycefotaxime sodium	Antibiotic Bacterial	Infection
Cefetamet sodium is a cephalosporin antibiotic. Cefetamet sodium has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-108193

GW 328267	Adenosine Receptor	Inflammation/Immunology
GW 328267 is an A2A receptor agonist. GW 328267 can be used for research of asthma, COPD and upper respiratory inflammatory disease .

HY-124235

SK&F 97574 hydrochloride	Na+/K+ ATPase	Others
SK&F 97574 hydrochloride is a reversible inhibitor for H+/K+ ATPase, that reduces gastric acid secretion and promotes the healing of acid-related upper gastrointestinal ulcers .

HY-116953

Lipoxin B4 LXB4	Endogenous Metabolite	Inflammation/Immunology
Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .

HY-113008S1

Urocanic acid-13C3	Endogenous Metabolite	Cancer
Urocanic acid- ¹³C₃ is the ¹³C labeled Urocanic acid[1]. Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR)[2].

HY-136338

Cimetidine sulfoxide Cimetidine sulphoxide	Histamine Receptor	Inflammation/Immunology
Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H₂-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment .

HY-A0111R

Cefetamet (Standard)	Antibiotic Bacterial	Infection
Cefetamet (Standard) is the analytical standard of Cefetamet. This product is intended for research and analytical applications. Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-121226

Karakin	Others	Metabolic Disease
Karakin is a nitro toxin derived from Lotus pedunculatus. Karakin is hydrolysed rapidly to 3-NPA in gut tissue of grass grub larvae, which is enzymic and occurred mainly in the upper half of the digestive tract .

HY-N0455B

L-Arginine (L-glutamate) Maximum Cited Publications 9 Publications Verification (S)-(+)-Arginine (L-glutamate)	Endogenous Metabolite NO Synthase	Metabolic Disease
L-Arginine L-glutamate ((S)-(+)-Arginine L-glutamate) is the nitrogen donor for synthesis of nitric oxide. L-Arginine L-glutamate can be used for upper gastrointestinal hypofunction or dysfunction like functional dyspepsia research .

HY-N0677

Dehydroandrographolide succinate	Influenza Virus	Infection Inflammation/Immunology Cancer
Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .

HY-P2990

Enteropeptidase TMPRSS15	Ser/Thr Protease	Metabolic Disease
Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. Enteropeptidase is associated with the brush border membrane (BBM) of the enterocytes in the upper small intestine. Trypsinogen is the primary substrate for Enteropeptidase. Enteropeptidase is involved in digestion in humans and animals .

HY-B1164A

Bromopride hydrochloride	Dopamine Receptor	Neurological Disease
Bromopride hydrochloride is a prokinetic drug with antiemetic activity. Bromopride hydrochloride is used to suppress nausea and vomiting, especially in the management of upper gastrointestinal dysmotility. Bromopride hydrochloride, as a dopamine D2 receptor antagonist, is clinically used to suppress functional dyspepsia, gastric retention and vomiting caused by various reasons .

HY-A0161S

Chlophedianol-13C6 Clofedanol-¹³C₆; Calmotusin-¹³C₆; NSC 113595-¹³C₆	Isotope-Labeled Compounds	Infection
Chlophedianol- ¹³C₆ is the ¹³C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2][3].

HY-N0677A

Kalii Dehydrographolidi Succinas Potassium dehydroandrographolide succinate	Antibiotic	Infection Inflammation/Immunology Cancer
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .

HY-12498

GV-58	Calcium Channel	Neurological Disease
GV-58 is a novel N- and P/Q-type calcium (Ca ²⁺) channel agonist with EC₅₀s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca ²⁺ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research .

HY-P2317

Cecropin P1, porcine	Bacterial Endogenous Metabolite	Infection
Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection .

HY-P2317A

Cecropin P1, porcine acetate	Bacterial Endogenous Metabolite	Infection
Cecropin P1, porcine acetate is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine acetate shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine acetate shows antiviral activity and inhibits PRRSV infection .

HY-136338R

Cimetidine sulfoxide (Standard)	Histamine Receptor	Inflammation/Immunology
Cimetidine sulfoxide (Standard) is the analytical standard of Cimetidine sulfoxide. This product is intended for research and analytical applications. Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment .

HY-B1446

Esomeprazole magnesium 5 Publications Verification (S)-Omeprazole magnesium; (-)-Omeprazole magnesium	Proton Pump	Endocrinology Cancer
Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H ⁺, K ⁺-ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research . Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H ⁺-ATPases .

HY-17022

Esomeprazole magnesium trihydrate 5 Publications Verification (S)-Omeprazole magnesium trihydrate; (-)-Omeprazole magnesium trihydrate	Proton Pump	Endocrinology Cancer
Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally active H ⁺, K ⁺-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research . Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H ⁺-ATPases .

HY-W008634

Bropirimine	Toll-like Receptor (TLR)	Cancer
Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract .

HY-E70364

IgdE protease	Biochemical Assay Reagents	Inflammation/Immunology
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .

HY-B0189B

Mosapride citrate dihydrate TAK-370 citrate dihydrate; AS-4370 citrate dihydrate	5-HT Receptor Potassium Channel Cytochrome P450	Metabolic Disease Cancer
Mosapride (TAK-370) citrate dehydrate is a gastroprokinetic agent with 5-hydroxytryptamine₄ receptor agonist activity and has been widely used in the research of a variety of gastrointestinal disorders. Mosapride citrate dihydrate potently inhibits Kv4.3 in a concentration-dependent manner with IC₅₀ values of 15.2 μM . Mosapride citrate dihydrateselectively stimulates upper GI motility in vivo .

HY-N0081

(±)-Praeruptorin A	Calcium Channel	Infection Cardiovascular Disease
(±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca ²⁺-influx blocker .

HY-N0702

Tenuifolin	Beta-secretase Cholinesterase (ChE)	Neurological Disease
Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD) .

HY-17022R

Esomeprazole magnesium trihydrate (Standard)	Proton Pump	Endocrinology Cancer
Esomeprazole magnesium (trihydrate) (Standard) is the analytical standard of Esomeprazole magnesium (trihydrate). This product is intended for research and analytical applications. Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally active H ⁺, K ⁺-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research . Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H ⁺-ATPases .

HY-N0702R

Tenuifolin (Standard)	Beta-secretase Cholinesterase (ChE)	Neurological Disease
Tenuifolin (Standard) is the analytical standard of Tenuifolin. This product is intended for research and analytical applications. Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD) .

HY-N0081R

(±)-Praeruptorin A (Standard)	Calcium Channel	Infection Cardiovascular Disease
(±)-Praeruptorin A (Standard) is the analytical standard of (±)-Praeruptorin A. This product is intended for research and analytical applications. (±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker .

Cat. No.	Product Name	Target	Research Area