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vaginal

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

1

Inhibitory Antibodies

5

Natural
Products

2

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W015591
    Mandelic acid
    1 Publications Verification

    (±)-Mandelic acid; DL-Mandelic acid

    		 Bacterial Endogenous Metabolite Infection
    Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation .
    Mandelic acid
  • HY-108293
    Promestriene

    		Estrogen Receptor/ERR Endocrinology Cancer
    Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed .
    Promestriene
  • HY-B0722
    Histamine dihydrochloride
    Maximum Cited Publications
    10 Publications Verification

    		 Endogenous Metabolite Reactive Oxygen Species Metabolic Disease Cancer
    Histamine dihydrochloride is a reactive oxygen species (ROS) inhibitor. Histamine dihydrochloride can suppress ROS production and work together with IL-2 to activate T cells and NK cells, leading to immune activation in the tumor microenvironment, which consequently kills acute myeloid leukemia (AML) cells. Histamine dihydrochloride can cause a reduction in vaginal tetrazo reduction, increased epithelial growth, and heightened keratinization in mouse models of ovariectomy. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine dihydrochloride
  • HY-100267
    Chlordantoin

    Clodantoin

    		 Fungal Infection
    Chlordantoin is an antifungal agent and has the potential for vaginal candidiasis treatment.
    Chlordantoin
  • HY-B1790
    Terconazole

    R42470

    		 Fungal Infection
    Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.
    Terconazole
  • HY-W015591R
    Mandelic acid (Standard)

    		Bacterial Endogenous Metabolite Infection
    Mandelic acid (Standard) is the analytical standard of Mandelic acid. This product is intended for research and analytical applications. Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation .
    Mandelic acid (Standard)
  • HY-108293R
    Promestriene (Standard)

    		Estrogen Receptor/ERR Endocrinology Cancer
    Promestriene (Standard) is the analytical standard of Promestriene. This product is intended for research and analytical applications. Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed .
    Promestriene (Standard)
  • HY-146190
    Callophycin A

    		Bacterial Antibiotic Infection Inflammation/Immunology
    Callophycin A, a red seaweed derived metabolite, possessing potent activity against Candida albicans with MIC of 62.5~250 mg/L. Callophycin A significantly reduces fungal burden of vaginal candidiasis induced mice, also decreases inflammatory response and immune molecules .
    Callophycin A
  • HY-113863
    Rilopirox

    HOE 351

    		 Fungal Infection
    Rilopirox (HOE 351) is a hydroxy-pyridone compound with antimycotic properties. Rilopirox, a chelating agent, can inhibit catalase. Rilopirox inhibits the respiratory chain. Rilopirox inhibits growth of yeast isolates with a MIC50 of 4 μg/mL. Rilopirox has the potential for vaginal candidosis and oropharyngeal Candida infections research .
    Rilopirox
  • HY-B0722R
    Histamine (dihydrochloride) (Standard)

    		Endogenous Metabolite Reactive Oxygen Species Metabolic Disease Cancer
    Histamine (dihydrochloride) (Standard) is the analytical standard of Histamine (dihydrochloride). This product is intended for research and analytical applications. Histamine dihydrochloride is a reactive oxygen species (ROS) inhibitor. Histamine dihydrochloride can suppress ROS production and work together with IL-2 to activate T cells and NK cells, leading to immune activation in the tumor microenvironment, which consequently kills acute myeloid leukemia (AML) cells. Histamine dihydrochloride can cause a reduction in vaginal tetrazo reduction, increased epithelial growth, and heightened keratinization in mouse models of ovariectomy. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine (dihydrochloride) (Standard)
  • HY-B1790S
    Terconazole-d4

    R42470-d4

    		 Fungal Infection
    Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.
    Terconazole-d4
  • HY-B1790R
    Terconazole (Standard)

    		Fungal Infection
    Terconazole (Standard) is the analytical standard of Terconazole. This product is intended for research and analytical applications. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.
    Terconazole (Standard)
  • HY-W015591S
    Mandelic acid-2,3,4,5,6-d5

    (±)-Mandelic acid-2,3,4,5,6-d5; DL-Mandelic acid-2,3,4,5,6-d5

    		 Bacterial Endogenous Metabolite Infection
    Mandelic acid-2,3,4,5,6-d5 is the deuterium labeled Mandelic acid. Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation[1][2].
    Mandelic acid-2,3,4,5,6-d5
  • HY-107906
    Conjugated estrogen sodium

    		Estrogen Receptor/ERR Endocrinology
    Conjugated estrogen sodium is a medication composed of a blend of estrogen hormones, utilized in the treatment of moderate to severe hot flashes, vaginal changes, and various other symptoms associated with menopause or decreased estrogen levels.
    Conjugated estrogen sodium
  • HY-B0238R
    Amorolfine (hydrochloride) (Standard)

    		Fungal Antibiotic Infection
    Amorolfine (hydrochloride) (Standard) is the analytical standard of Amorolfine (hydrochloride). This product is intended for research and analytical applications. Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis .
    Amorolfine (hydrochloride) (Standard)
  • HY-B0238
    Amorolfine hydrochloride

    Ro 14-4767/002

    		 Fungal Antibiotic Infection
    Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis .
    Amorolfine hydrochloride
  • HY-B0293A
    Butoconazole
    1 Publications Verification

    		 Fungal Infection
    Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
    Butoconazole
  • HY-B0723
    Ospemifene
    2 Publications Verification

    FC-1271a

    		 Estrogen Receptor/ERR Cancer
    Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with Kis of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer .
    Ospemifene
  • HY-B0359
    Fenticonazole Nitrate
    4 Publications Verification

    REC 15-1476

    		 Fungal Antibiotic Infection
    Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
    Fenticonazole Nitrate
  • HY-142016
    Retinol, palmitate, 9-cis,13-cis-

    9-cis,13-cis-Retinyl palmitate; 9-cis,13-cis-Vitamin A palmitate

    		 Biochemical Assay Reagents Others
    Retinol, palmitate, 9-cis,13-cis- is the palmitate isomer of vitamin A. Retinol, palmitate, 9-cis,13-cis- can be test bioactivity through rat vaginal smear assays .
    Retinol, palmitate, 9-cis,13-cis-
  • HY-B0293
    Butoconazole nitrate
    1 Publications Verification

    RS 35887

    		 Fungal Infection
    Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
    Butoconazole nitrate
  • HY-B1360
    Chlorquinaldol
    5 Publications Verification

    Chloquinan

    		 Antibiotic Bacterial Fungal β-catenin Apoptosis Infection Cancer
    Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .
    Chlorquinaldol
  • HY-117166
    Naftoxate

    K-F-224

    		 Bacterial Infection
    Naftoxate is an ester compound containing aminomethylsulfate, and its ammonium salt analog can inhibit free thiols to chemically weaken the reactive oxygen species (ROS)-sensitive anaerobic bacterium Trichomonas vaginalis and inhibit common pathogens causing vaginal infections: Candida albicans and Staphylococcus aureus .
    Naftoxate
  • HY-Y0850E
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

    PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)

    		 Biochemical Assay Reagents Cardiovascular Disease Cancer
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)
  • HY-B1360R
    Chlorquinaldol (Standard)

    		Antibiotic Bacterial Fungal β-catenin Apoptosis Infection Cancer
    Chlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .
    Chlorquinaldol (Standard)
  • HY-P991072
    MB-66

    MAPP-66

    		 HIV HSV Infection
    MB-66 (MAPP-66) is a fully human IgG1 antibody that targets HSV and HIV. MB-66 is a monoclonal antibody film for vaginal application. The isotype control for MB-66 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
    MB-66
  • HY-B0359R
    Fenticonazole (Nitrate) (Standard)

    		Fungal Antibiotic Infection
    Fenticonazole (Nitrate) (Standard) is the analytical standard of Fenticonazole (Nitrate). This product is intended for research and analytical applications. Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
    Fenticonazole (Nitrate) (Standard)
  • HY-B0293R
    Butoconazole (nitrate) (Standard)

    		Fungal Infection
    Butoconazole (nitrate) (Standard) is the analytical standard of Butoconazole (nitrate). This product is intended for research and analytical applications. Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
    Butoconazole (nitrate) (Standard)
  • HY-103209
    Rec 15/2615 hydrochloride

    		Adrenergic Receptor Cardiovascular Disease Endocrinology
    Rec 15/2615 hydrochloride is a potent and selective α-1B adrenoceptor antagonist with Ki values of 1.9 nM, 0.3 nM, 2.6 nM for α1A, α1B, α1D, respectively. Rec 15/2615 hydrochloride modulates vaginal smooth muscle contractility and genital engorgement .
    Rec 15/2615 hydrochloride
  • HY-P10653
    C5A

    		HCV HIV Infection
    C5A is a microbicidal peptide, anti-hepatitis C virus (HCV), and anti-HIV agent. C5A disrupts the membrane integrity of the HIV virion as well as the integrity of the conical capsid core that surrounds the viral genome. C5A inhibits in vitro infectivity of a broad range of primary HIV isolates in various primary target cells. C5A protects mice against vaginal and rectal HIV challenges .
    C5A

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