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Results for "

ventricular tachyarrhythmias

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0772A
    Nifekalant hydrochloride

    MS-551

    		 Potassium Channel Cardiovascular Disease
    Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 μM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research .
    Nifekalant hydrochloride
  • HY-B1167
    Ajmaline

    Cardiorythmine; (+)-Ajmaline

    		 Sodium Channel Cardiovascular Disease
    Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .
    Ajmaline
  • HY-126028A
    (+)-Sotalol

    (S)-Sotalol

    		 Adrenergic Receptor Cardiovascular Disease Neurological Disease
    (+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol (HY-103196). Sotalol is an orally active, non-selective β-adrenergic receptor blocker. (+)-Sotalol is an antiarrhythmic agent. (+)-Sotalol can prolong action potential duration in isolated cardiac muscle .
    (+)-Sotalol
  • HY-A0236A
    Aprindine hydrochloride

    		Potassium Channel Cardiovascular Disease
    Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research.
    Aprindine hydrochloride
  • HY-B0772
    Nifekalant

    MS-551 free base

    		 Potassium Channel Cardiovascular Disease
    Nifekalant (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 μM. Nifekalant can be used for refractory ventricular tachyarrhythmias research .
    Nifekalant
  • HY-B0772AR
    Nifekalant hydrochloride (Standard)

    		Potassium Channel Cardiovascular Disease
    Nifekalant (hydrochloride) (Standard) is the analytical standard of Nifekalant (hydrochloride). This product is intended for research and analytical applications. Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 µM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research .
    Nifekalant hydrochloride (Standard)
  • HY-B1167R
    Ajmaline (Standard)

    		Sodium Channel Cardiovascular Disease
    Ajmaline (Standard) is the analytical standard of Ajmaline. This product is intended for research and analytical applications. Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .
    Ajmaline (Standard)
  • HY-106912A
    L-706000 free base

    MK 499 free base

    		 Potassium Channel Cardiovascular Disease
    L-706000 (MK 499) free base is a potent hERG channel blocker with an IC50 of 32 nM. L-706000 free base is a class III antiarrhythmic agent that can be used for the study of malignant ventricular tachyarrhythmias .
    L-706000 free base
  • HY-111013
    VK-II-86

    		Others Cardiovascular Disease
    VK-II-86 is a Carvedilol (HY-B0006) analogue lacking antagonist activity at β-adrenoceptors, in hypokalaemia. VK-II-86 prevents hypokalaemia-induced ventricular arrhythmia through multi-channel effects. VK-II-86 prevents all hypokalaemia-induced changes in ion channel activity and oxidative stress .
    VK-II-86

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