visual

By Targets:	Apoptosis (1) Biochemical Assay Reagents (1) Dopamine Receptor (1) Endogenous Metabolite (1) Fluorescent Dye (3) HCN Channel (2) MAP3K (1) p38 MAPK (1) Potassium Channel (2) VEGFR (1)
By Research Areas:	Cardiovascular Disease (1) Inflammation/Immunology (2) Metabolic Disease (5) Neurological Disease (6)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100743

DL-AP4 2-Amino-4-phosphonobutyric acid	Others	Neurological Disease Metabolic Disease
DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent K_d of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system .

HY-19720

Emixustat ACU-4429	Others	Metabolic Disease
Emixustat is an orally active RPE65 inhibitor with an IC₅₀ value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .

HY-19720A

Emixustat hydrochloride ACU-4429 hydrochloride	Others	Metabolic Disease
Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC₅₀ value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .

HY-P99116

Faricimab RG7716	VEGFR	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) .

HY-121650A

ADTN hydrobromide	Dopamine Receptor	Neurological Disease
ADTN hydrobromide is a long-acting dopamine agonist. ADTN hydrobromide significantly decreases the behavioral visual threshold of DA-IPC-depleted zebrafish .

HY-136564A

DAD	Potassium Channel	Neurological Disease
DAD is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD is a third-generation photoswitch that responds to visible light. DAD has the potential for restoring visual function .

HY-136564

DAD dichloride	Potassium Channel	Neurological Disease
DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function .

HY-W016568

Isoxanthopterin	Others	Others
Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .

HY-D1247

Hydroxynaphthol Blue	Fluorescent Dye	Others
Hydroxynaphthol Blue enables visual tube closure detection. Hydroxynaphthol Blue shows high specificity for the gene encoding Ara h 1 for visual field detection of peanut allergens .

HY-110262

MSC 2032964A	MAP3K p38 MAPK	Inflammation/Immunology
MSC 2032964A is an orally active, selective inhibitor for apoptosis signal-regulating kinase 1(ASK1) with IC₅₀ of 96 nM. MSC 2032964A preserves the visual responses in EAE mice model and exhibits potency in ameliorating the neuroinflammation .

HY-137016

8-Pcpt-cGMP	HCN Channel	Neurological Disease
8-Pcpt-cGMP is an agonist for cyclic nucleotide-gated (CNG) channel with an EC₅₀ of 0.5 μM. 8-Pcpt-cGMP exhibits good membrane permeability. 8-Pcpt-cGMP can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction .

HY-111391A

Resazurin (sodium), indicator Diazoresorcinol (sodium), indicator	Biochemical Assay Reagents	Others
Resazurin sodium, indicator is a blue dye commonly used as a redox indicator in various chemical reactions, especially in microbiology and cell culture. Resazurin sodium, indicator has unique chemical properties that make it an effective tool for monitoring changes in the metabolic activity of cells and microorganisms. When reduced, Resazurin turns from blue to pink, providing a visual indication of metabolic activity.

HY-125457

α-Naphtholbenzein p-Naphtolbenzein	Fluorescent Dye	Others
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations .

HY-W004500

All-trans-retinal 1 Publications Verification	Endogenous Metabolite Apoptosis	Metabolic Disease
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

HY-D2338

PMBD	Fluorescent Dye	Others
PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

HY-137016A

8-Pcpt-cGMP sodium	HCN Channel	Neurological Disease
8-Pcpt-cGMP sodium is the sodium salt form of 8-Pcpt-cGMP (HY-137016). 8-Pcpt-cGMP sodium is an agonist for cyclic nucleotide-gated (CNG) channel with an EC₅₀ of 0.5 μM. 8-Pcpt-cGMP sodium exhibits good membrane permeability. 8-Pcpt-cGMP sodium can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction .

Cat. No.	Product Name	Type

HY-D2338

PMBD	Fluorescent Dyes/Probes
PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

PMBD

Fluorescent Dyes/Probes

PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

Cat. No.	Product Name	Type

HY-111391A

Resazurin (sodium), indicator Diazoresorcinol (sodium), indicator	Indicators
Resazurin sodium, indicator is a blue dye commonly used as a redox indicator in various chemical reactions, especially in microbiology and cell culture. Resazurin sodium, indicator has unique chemical properties that make it an effective tool for monitoring changes in the metabolic activity of cells and microorganisms. When reduced, Resazurin turns from blue to pink, providing a visual indication of metabolic activity.

Resazurin (sodium), indicator

Diazoresorcinol (sodium), indicator

Indicators

Resazurin sodium, indicator is a blue dye commonly used as a redox indicator in various chemical reactions, especially in microbiology and cell culture. Resazurin sodium, indicator has unique chemical properties that make it an effective tool for monitoring changes in the metabolic activity of cells and microorganisms. When reduced, Resazurin turns from blue to pink, providing a visual indication of metabolic activity.

HY-121650A

ADTN hydrobromide	Biochemical Assay Reagents
ADTN hydrobromide is a long-acting dopamine agonist. ADTN hydrobromide significantly decreases the behavioral visual threshold of DA-IPC-depleted zebrafish .

HY-D1247

Hydroxynaphthol Blue	Biochemical Assay Reagents
Hydroxynaphthol Blue enables visual tube closure detection. Hydroxynaphthol Blue shows high specificity for the gene encoding Ara h 1 for visual field detection of peanut allergens .

HY-125457

α-Naphtholbenzein p-Naphtolbenzein	Indicators
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations .

Cat. No.	Product Name	Target	Research Area

HY-P99116

Faricimab RG7716	VEGFR	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W004500

All-trans-retinal 1 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

HY-W016568

Isoxanthopterin	Structural Classification Natural Products Animals Source classification	Others
Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .

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Fluorescent Dye

Biochemical Assay Reagents

Inhibitory Antibodies

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