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Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active.

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Seclazone Chemical Structure

Seclazone Chemical Structure

CAS No. : 29050-11-1

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Based on 1 publication(s) in Google Scholar

Seclazone Related Antibodies

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Description

Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active[1].

In Vivo

Seclazone (220 mg/kg; p.o.; dietary, daily) inhibits the development of adjuvant-induced polyarthritis in rats[1].
Seclazone significantly lowers the fever induced in rats by administration of a yeast suspension[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Charles River rats (150-170 g) [1]
Dosage: 220 mg/kg
Administration: Oral administration, dietary, daily
Result: Inhibited adjuvant-induced polyarthritis
Molecular Weight

225.63

Formula

C10H8ClNO3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N(OCC2)C2OC3=CC=C(Cl)C=C13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 14.29 mg/mL (63.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4320 mL 22.1602 mL 44.3203 mL
5 mM 0.8864 mL 4.4320 mL 8.8641 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4320 mL 22.1602 mL 44.3203 mL 110.8009 mL
5 mM 0.8864 mL 4.4320 mL 8.8641 mL 22.1602 mL
10 mM 0.4432 mL 2.2160 mL 4.4320 mL 11.0801 mL
15 mM 0.2955 mL 1.4773 mL 2.9547 mL 7.3867 mL
20 mM 0.2216 mL 1.1080 mL 2.2160 mL 5.5400 mL
25 mM 0.1773 mL 0.8864 mL 1.7728 mL 4.4320 mL
30 mM 0.1477 mL 0.7387 mL 1.4773 mL 3.6934 mL
40 mM 0.1108 mL 0.5540 mL 1.1080 mL 2.7700 mL
50 mM 0.0886 mL 0.4432 mL 0.8864 mL 2.2160 mL
60 mM 0.0739 mL 0.3693 mL 0.7387 mL 1.8467 mL
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Seclazone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Seclazone29050-11-1Othersanti-BradykininpolyarthritisantipyreticdiureticInhibitorinhibitorinhibit

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