2. GPCR/G Protein
  3. Secretin Receptor
  4. Secretin (28-54), human TFA

Secretin (28-54), human TFA  (Synonyms: Human secretin TFA)

Cat. No.: HY-P1465A Purity: 98.62%
Data Sheet
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COA
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Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors.

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Secretin (28-54), human TFA Chemical Structure

Secretin (28-54), human TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors[1].

In Vitro

Secretin is a hormone produced and secreted from the endocrine S cells in response to the gastric acid and lipid components. Secretin potentiates enzyme secretion from the acinar cell. Secretin is also a putative mitogen to promote pancreatic growth. In the stomach and gall bladder, Secretin inhibits gastric emptying and acid release and stimulates biliary output of water and bicarbonate. Secretin elicits its biological effects by interacting with specific cell surface receptors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
NCT NumberSponsorConditionStart DatePhase
NCT03617861Mayo Clinic|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Dyspepsia|Healthy
November 7, 2018Phase 1|Phase 2
NCT01094600Columbia University
Pancreatic Cancer
June 2012Not Applicable
NCT00587132Mayo Clinic|ChiRhoClin, Inc.
Pancreatic Cancer
November 2006Phase 1|Phase 2
Molecular Weight

3039.46 (free base)

Formula

C130H220N44O40.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2
Sequence Shortening

HSDGTFTSELSRLREGARLQRLLQGLV-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation

Purity: 98.62%

Data Sheet (264 KB) SDS (252 KB)

COA (240 KB)RP-HPLC (208 KB)MS (175 KB)

Handling Instructions (2659 KB)
References
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Secretin (28-54), human TFA Related Classifications

Keywords:

Secretin (28-54), humanHuman secretinSecretin ReceptorSCTRSecretinhumanreceptorsdigestivehormoneInhibitorinhibitorinhibit

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