2. GPCR/G Protein
  3. Secretin Receptor
  4. Secretin (28-54), human

Secretin (28-54), human  (Synonyms: Human secretin)

Cat. No.: HY-P1465 Purity: 99.33%
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Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors.

For research use only. We do not sell to patients.

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Secretin (28-54), human Chemical Structure

Secretin (28-54), human Chemical Structure

CAS No. : 108153-74-8

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1 mg USD 120 In-stock
5 mg USD 360 In-stock
10 mg USD 558 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Secretin (28-54), human:

Secretin (28-54), human Related Antibodies

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Description

Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors[1].

IC50 & Target

Human secretin receptor[1]
In Vitro

Secretin is a hormone produced and secreted from the endocrine S cells in response to the gastric acid and lipid components. Secretin potentiates enzyme secretion from the acinar cell. Secretin is also a putative mitogen to promote pancreatic growth. In the stomach and gall bladder, Secretin inhibits gastric emptying and acid release and stimulates biliary output of water and bicarbonate. Secretin elicits its biological effects by interacting with specific cell surface receptors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Secretin (28-54), human Related Antibodies
Clinical Trial
Molecular Weight

3039.46

Formula

C130H220N44O40
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2
Sequence Shortening

HSDGTFTSELSRLREGARLQRLLQGLV-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (32.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3290 mL 1.6450 mL 3.2901 mL
5 mM 0.0658 mL 0.3290 mL 0.6580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3290 mL 1.6450 mL 3.2901 mL 8.2251 mL
5 mM 0.0658 mL 0.3290 mL 0.6580 mL 1.6450 mL
10 mM 0.0329 mL 0.1645 mL 0.3290 mL 0.8225 mL
15 mM 0.0219 mL 0.1097 mL 0.2193 mL 0.5483 mL
20 mM 0.0165 mL 0.0823 mL 0.1645 mL 0.4113 mL
25 mM 0.0132 mL 0.0658 mL 0.1316 mL 0.3290 mL
30 mM 0.0110 mL 0.0548 mL 0.1097 mL 0.2742 mL
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Secretin (28-54), human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Secretin (28-54), human108153-74-8Human secretinSecretin ReceptorSCTRSecretinhumanreceptorsdigestivehormoneInhibitorinhibitorinhibit

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